Publications
Below are a few of the recent publications relating to Statistics in Medicine and Molecular Biology arising from members of this research theme. Fuller details of an individual's publications can be found by following the links from the 'People' page.
Trend shifts in road traffic collisions: an application of Hidden Markov Models and generalised additive models to assess the impact of the 20mph speed limit policy in Edinburgh
Popov, V., Nightingale, G., Williams, A. J., Kelly, P., Jepson, R., Milton, K. & Kelly, M., 11 Jan 2021, In: Environment and Planning B: Planning and Design. OnlineFirst
CamGFR v2: a new model for estimating the glomerular filtration rate from standardized or non-standardized creatinine in patients with cancer
Williams, E. H., Flint, T. R., Connell, C. M., Giglio, D., Lee, H., Ha, T., Gablenz, E., Bird, N. J., Weaver, J. M. J., Potts, H., Whitley, C. T., Bookman, M. A., Lynch, A. G., Meyer, H. V., Tavaré, S. & Janowitz, T., (2020) Clinical cancer research online first
Multiplexing information flow through dynamic signalling systems
Minas, G., Woodcock, D. J., Ashall, L., Harper, C. V., White, M. R. H. & Rand, D. A., (2020) PLoS Computational Biology. 16, 8 , 18 p., e1008076.
Deciphering the genomic, epigenomic and transcriptomic landscapes of pre-invasive lung cancer lesions
Texeira, V. H., Pipinikas, C. P., Pennycuick, A., Lee-Six, H., Chandrasekharan, D., Beane, J., Morris, T. J., Karpathakis, A., Feber, A., Breeze, C. E., Ntolios, P., Hynds, R. E., Falzon, M., Capitanio, A., Carroll, B., Durrenberger, P. F., Hardavella, G., Brown, J. M., Lynch, A. G., Farmery, H. & 12 others, (2019) Nature Medicine. 25, 3, p. 517-525
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
Al-Shahi Salman, R., Minks, D. P., Mitra, D., et al. (including Rosemary Bailey) (2019) The Lancet Neurology. 18, 7, p. 643-652
Modelling reassurances of clinicians with Hidden Markov models
Popov, V., Ellis-Robinson, A. & Humphris, G. (2019) BMC Medical Research Methodology. 19, 10
Parameter sensitivity analysis for biochemical reaction networks
Minas, G. & Rand, D. A., (2019) Mathematical Biosciences and Engineering. 16, 5, p. 3965-3987
Telomerecat: A Ploidy-Agnostic Method For Estimating Telomere Length From Whole Genome Sequencing Data
Farmery JHR, Smith ML, NIHR BioResource - Rare Diseases and Lynch AG (2018) Scientific Reports 8, 1300
Inferring transcriptional logic from multiple dynamic experiments.
Minas, Giorgos and Dafyd J. and Rand, David A. and Finkenstädt, Bärbel (2017). Bioinformatics,
Statistical issues in first-in-human studies on BIA 10-2474: neglected comparison of protocol against practice
Bird, S. M., Bailey, R. A., Grieve, A. P. & Senn, S. 15 Mar 2017 In : Pharmaceutical Statistics. 16, 2, p. 100-106 7 p.
New Model for Estimating Glomerular Filtration Rate in Patients With Cancer.
Janowitz T, Williams EH, Marshall A, Ainsworth N, Thomas PB, Sammut SJ, Shepherd S, White J, Mark PB, Lynch AG, Jodrell DI, Tavaré S, and Earl H (2017) Journal of Clinical Oncology
ReTrOS: A MATLAB toolbox for reconstructing and analysing transcriptional activity from gene and protein expression data.
Minas, Giorgos and Momiji, Hiroshi and Jenkins, Dafyd J. and Costa, Maria J. and Rand, David A. and Finkenstädt, Bärbel (2017). BMC Bioinformatics, 18:316.
The Importance of DNA methylation in Prostate Cancer development
Massie CE, Mills IG, Lynch AG (2017) The Journal of Steroid Biochemistry and Molecular Biology 166 1-15
Exploring Data From Genetic Association Studies Using Bayesian Variable Selection and the Dirichlet Process: Application to Searching for Gene × Gene Patterns
Papathomas, M., Molitor, J., Hoggart, C., Hastie, D. & Richardson, S. Sep 2012 In : Genetic Epidemiology. 36, 6, p. 663-674
Multinomial logistic regression modelling of cardiologists’ awareness of the impact of Air Pollution on cardiovascular disease in Vietnam and the Philippines
Nguyen, Q. T., Naguib, R. N. G., Papathomas, M., Shaker, M. H., Culaba, A. B., Wickramasinghe, N. & Ton, T. N. 2012 In : International Journal of Biomedical Engineering and Technology. 10, p. 38-54