Publications
2024
Sangini S Sheth #, Ji Eun Oh #, Stefania Bellone, Eric R Siegel, Michelle Greenman, Levent Mutlu, Blair McNamara, Shefali Pathy, Mitchell Clark, Masoud Azodi, Gary Altwerger, Vaagn Andikyan, Gloria Huang, Elena Ratner, Daniel J Kim, Akiko Iwasaki, Angelique W Levi, Natalia Buza, Pei Hui, Sean Flaherty, Peter E Schwartz, Alessandro D Santin. Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147). Clinical Cancer Research 2024;30(9):1768-1777
Eun-Gang Lee, Ji Eun Oh. From neglect to spotlight: the underappreciated role of B cells in cutaneous inflammatory diseases. Frontiers in Immunology 2024;15:1328785
2023
Vivian Y Lim, Xing Feng, Runfeng Miao, Sandra Zehentmeier, Nathan Ewing-Crystal, Moonyoung Lee, Alexei V Tumanov, Ji Eun Oh, Akiko Iwasaki, Andrew Wang, Jungmin Choi, Joao P Pereira. Mature B cells and mesenchymal stem cells control emergency myelopoiesis. Life Science Alliance 2023;6:e202301924
2022
Choong Man Lee, Ji Eun Oh. Resident memory B cells in barrier tissues. Frontiers in Immunology 2022;13:953088. doi: 10.3389/fimmu.2022.953088
Young Joon Park, Byeong Hoon Kang, Hyun-Jin Kim, Ji Eun Oh, Heung Kyu Lee. A microbiota-dependent subset of skin macrophages protects against cutaneous bacterial infection. Frontiers in Immunology 2022;13:799598
Manik Kuchroo, Jessie Huang, Patrick Wong, Jean-Christophe Grenier, Dennis Shung, Alexander Tong, Carolina Lucas, Jon Klein, Daniel B Burkhardt, Scott Gigante, Abhinav Godavarthi, Bastian Rieck, Benjamin Israelow, Michael Simonov, Tianyang Mao, Ji Eun Oh, Julio Silva, Takehiro Takahashi, Camila D Odio, Arnau Casanovas-Massana, John Fournier, Shelli Farhadian, Charles S Dela Cruz, Albert I Ko, Matthew J Hirn, F Perry Wilson, Julie G Hussin, Guy Wolf, Akiko Iwasaki, Smita Krishnaswamy. Multiscale PHATE identifies multimodal signatures of COVID-19. Nature Biotechnology 2022;40:681-691
Jonathan Klein, Anderson F Brito, Paul Trubin, Peiwen Lu, Patrick Wong, Tara Alpert, Mario A Peña-Hernández, Winston Haynes, Kathy Kamath, Feimei Liu, Chantal B F Vogels, Joseph R Fauver, Carolina Lucas, Jieun Oh, Tianyang Mao, Julio Silva, Anne L Wyllie, M Catherine Muenker, Arnau Casanovas-Massana, Adam J Moore, Mary E Petrone, Chaney C Kalinich, Charles Dela Cruz, Shelli Farhadian, Aaron Ring, John Shon, Albert I Ko, Nathan D Grubaugh, Benjamin Israelow, Akiko Iwasaki, Marwan M Azar, for the Yale Implementing Medical and Public Health Action Against Coronavirus in Connecticut (IMPACT) Research Team. Longitudinal immune profiling of a severe acute respiratory syndrome coronavirus 2 reinfection in a solid organ transplant recipient. The Journal of Infectious Diseases 2022;225:374-384
2021
Ji Eun Oh*, Eric Song*, Miyu Moriyama*, Patrick Wong, Sophia Zhang, Ruoyi Jiang, Shirin Strohmeier, Steven H. Kleinstein, Florian Krammer, Akiko Iwasaki (*co-first author). Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA. Science Immunology 2021;6(66):5129
Yuping Cai, Daniel J Kim, Takehiro Takahashi, David I Broadhurst, Hong Yan, Shuangge Ma, Nicholas J W Rattray, Arnau Casanovas-Massana, Benjamin Israelow, Jon Klein, Carolina Lucas, Tianyang Mao, Adam J Moore, M Catherine Muenker, Ji Eun Oh, Julio Silva, Patrick Wong, Yale IMPACT Research team; Albert I Ko, Sajid A Khan, Akiko Iwasaki, Caroline H Johnson. Kynurenic acid may underlie sex-specific immune responses to COVID-19. Science Signaling 2021;14(690):eabf8483
Eric Song, Christopher M Bartley, Ryan D Chow, Thomas T Ngo, Ruoyi Jiang, Colin R Zamecnik, Ravi Dandekar, Rita P Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A Hawes, Bonny D Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer Chiarella, Benjamin Goldman-Israelow, Chantal BF Vogels, Nathan D Grubaugh, Arnau Casanovas-Massana, Brett S Phinney, Michelle Salemi, Jessa R Alexander, Juan A Gallego, Todd Lencz, Hannah Walsh, Anne E Wapniarski, Subhasis Mohanty, Carolina Lucas, Jon Klein, Tianyang Mao, Jieun Oh, Aaron Ring, Serena Spudich, Albert I Ko, Steven H Kleinstein, John Pak, Joseph L DeRisi, Akiko Iwasaki, Samuel J Pleasure, Michael R Wilson, Shelli F Farhadian. Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. Cell Reports Medicine 2021;2:100288
Eunjin Lee, Ji Eun Oh. Humoral immunity against SARS-CoV-2 and the impact on COVID-19 pathogenesis. Molecules and Cells 2021;44(6):392-400
Eric Y Wang*, Tianyang Mao*, Jon Klein*, Yile Dai*, John D Huck, Jillian R Jaycox, Feimei Liu, Ting Zhou, Benjamin Israelow, Patrick Wong, Andreas Coppi, Carolina Lucas, Julio Silva, Ji Eun Oh, Eric Song, Emily S Perotti, Neil S Zheng, Suzanne Fischer, Melissa Campbell, John B Fournier, Anne L Wyllie, Chantal B F Vogels, Isabel M Ott, Chaney C Kalinich, Mary E Petrone, Anne E Watkins, Yale IMPACT Team; Charles Dela Cruz, Shelli F Farhadian, Wade L Schulz, Shuangge Ma, Nathan D Grubaugh, Albert I Ko, Akiko Iwasaki, Aaron M Ring. Diverse functional autoantibodies in patients with COVID-19. Nature 2021;595(7866):283-288
Carolina Lucas*, Jon Klein*, Maria E Sundaram, Feimei Liu, Patrick Wong, Julio Silva, Tianyang Mao, Ji Eun Oh, Subhasis Mohanty, Jiefang Huang, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Benjamin Israelow, Chantal B F Vogels, M Catherine Muenker, C-Hong Chang, Arnau Casanovas-Massana, Adam J Moore, Joseph Zell, John B Fournier, Yale IMPACT Research Team; Anne L Wyllie, Melissa Campbell, Alfred Lee, Hyung J Chun, Nathan D Grubaugh, Wade L Schulz, Shelli Farhadian, Charles Dela Cruz, Aaron M Ring, Albert C Shaw, Adam V Wisnewski, Inci Yildirim, Albert I Ko, Saad Omer, Akiko Iwasaki. Delayed production of neutralizing antibodies correlates with fatal COVID-19. Nature Medicine 2021;27(7):1178-1186
Chae Won Kim, Ji Eun Oh†, Heung Kyu Lee† (†co-corresponding author). Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection. Immune Network 2021;21(1):e10
Jang Hyun Park, Hyun-Jin Kim, Chae Won Kim, Hyeon Cheol Kim, Yujin Jung, Hyun-Soo Lee, Yunah Lee, Young Seok Ju, Ji Eun Oh, Sung-Hong Park, Jeong Ho Lee, Sung Ki Lee, Heung Kyu Lee. Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors. Nature Immunology 2021;22(3):336-346
~2020
Takehiro Takahashi*, Mallory Ellingson*, Patrick Wong*, Benjamin Israelow*, Carolina Lucas*, Jon Klein*, Julio Silva*, Tianyang Mao*, Ji Eun Oh, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Feimei Liu, Amit Meir, Jonathan Sun, Eric Wang, Anne Louise Wyllie, Chantal BF Vogels, Rebecca Earnest, Sarah Lapidus, Isabel Ott, Adam Moore, Arnau Casanovas, Charles Dela Cruz, John Fournier, Camila Odio, Shelli Farhadian, Nathan Grubaugh, Wade Schultz, Albert Ko, Aaron Ring, Saad Omer, Akiko Iwasaki, Yale IMPACT research team. Sex differences in immune responses to SARS-CoV-2 that underlie disease outcomes. Nature 2020;588(7837):315-320
Chantal B. F. Vogels, Anderson F. Brito, Anne L. Wyllie, Joseph R. Fauver, Isabel M. Ott, Chaney C. Kalinich, Mary E. Petrone, Arnau Casanovas-Massana, M. Catherine Muenker, Daniel J. Kim, Adam J. Moore, Jonathan Klein, Peiwen Lu, Alice Lu-Culligan, Xiaodong Jiang, Eriko Kudo, Tianyang Mao, Miyu Moriyama, Ji Eun Oh, Annsea Park, Julio Silva, Eric Song, Takehiro Takahashi, Manabu Taura, Maria Tokuyama, Arvind Venkataraman, Orr-El Weizman, Patrick Wong, Yexin Yang, Nagarjuna R. Cheemarla, Elizabeth B. White, Sarah Lapidus, Rebecca Earnest, Bertie Geng, Pavithra Vijayakumar, Camila Odio, John Fournier, Santos Bermejo, Shelli Farhadian, Charles S. Dela Cruz, Akiko Iwasaki, Albert I. Ko, Marie L. Landry, Ellen F. Foxman and Nathan D. Grubaugh. Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets. Nature Microbiology 2020;5(10):1299-1305
Anne Louise Wyllie, John Fournier, Arnau Casanovas-Massana, Melissa Campbell, Maria Tokuyama, Pavithra Vijayakumar, Joshua L Warren, Bertie Geng, M Catherine Muenker, Adam J Moore, Chantal BF Vogels, Mary E Petrone, Isabel M Ott, Peiwen Lu, Arvind Venkataraman, Alice Lu-Culligan, Jonathan Klein, Rebecca Earnest, Michael Simonov, Rupak Datta, Ryan Handoko, Nida Naushad, Lorenzo R Sewanan, Jordan Valdez, Elizabeth B White, Sarah Lapidus, Chaney C Kalinich, Xiaodong Jiang, Daniel J Kim, Eriko Kudo, Melissa Linehan, Tianyang Mao, Miyu Moriyama, Ji Eun Oh, Annsea Park, Julio Silva, Eric Song, Takehiro Takahashi, Manabu Taura, Orr-El Weizman, Patrick Wong, Yexin Yang, Santos Bermejo, Camila Odio, Saad B Omer, Charles S Dela Cruz, Shelli Farhadian, Richard A Martinello, Akiko Iwasaki, Nathan D Grubaugh, Albert I Ko. Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2. New England Journal of Medicine 2020;383(13):1283-1286
Carolina Lucas*, Patrick Wong* , Jon Klein*, Tiago B R Castro*, Julio Silva, Maria Sundaram, Mallory K Ellingson, Tianyang Mao, Ji Eun Oh, Benjamin Israelow, Takehiro Takahashi, Maria Tokuyama, Peiwen Lu, Arvind Venkataraman, Annsea Park, Subhasis Mohanty, Haowei Wang, Anne L Wyllie, Chantal B F Vogels, Rebecca Earnest, Sarah Lapidus, Isabel M Ott, Adam J Moore, M Catherine Muenker, John B Fournier, Melissa Campbell, Camila D Odio, Arnau Casanovas-Massana, Yale IMPACT Team; Roy Herbst, Albert C Shaw, Ruslan Medzhitov, Wade L Schulz, Nathan D Grubaugh, Charles Dela Cruz, Shelli Farhadian, Albert I Ko, Saad B Omer, Akiko Iwasaki. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature 2020;584(7821):463-469
Hyeon Cheol Kim, Dong Sun Oh, Jang Hyun Park, Hyun-Jin Kim, Yong Bok Seo, Hye Jee Yoo, Hye Seon Jang, Jua Shin, Chae Won Kim, Myeong Seung Kwon, Hyun-Tak Jin, Sung Ki Lee, Ji Eun Oh†, Heung Kyu Lee† (†co-corresponding author). Multivalent DNA vaccine protects against genital herpes by T-cell immune induction in vaginal mucosa. Antiviral Research 2020;177:104755
Ji Eun Oh, Akiko Iwasaki (2019). ‘Mucosal Vaccines for Genital Herpes’, in Hiroshi Kiyono & David W. Pascual (ed.) Mucosal Vaccines: Innovation for Preventing Infectious Diseases. Elsevier Science.
Chae Won Kim, Hye Jee Yoo, Jang Hyun Park, Ji Eun Oh, Heung Kyu Lee. Exogenous interleukin-33 contributes to protective immunity via cytotoxic T-cell priming against mucosal influenza viral infection. Viruses 2019;11(9): E840
Ji Eun Oh*, Norifumi Iijima*, Eric Song, Peiwen Lu, Jonathan Klein, Ruoyi Jiang, Steven H. Kleinstein, Akiko Iwasaki (*co-first author). Migrant memory B cells secrete luminal antibody in the vagina. Nature 2019; 571(7763):122-126
Hi Eun Jung, Ye Ri Shim, Ji Eun Oh, Dong Sun Oh, Heung Kyu Lee. The autophagy Protein Atg5 Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells. Immune Network 2019;19(2):e12
Hi Eun Jung, Ji Eun Oh, Heung Kyu Lee. Cell-Penetrating Mx1 Enhances Anti-Viral Resistance against Mucosal Influenza Viral Infection. Viruses 2019;11(2):E109
Wooseong Lee, Seung-Hoon Lee, Minwoo Kim, Jae-Su Moon, Geon-Woo Kim, Hae-Gwang Jung, In-Hwang Kim, Ji Eun Oh, Hi Eun Jung, Heung Kyu Lee, Keun Bon Ku, Dae-Gyun Ahn, Seong-Jun Kim, Kun-Soo Kim, Jong-Won Oh. Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. Nature Communications 2018;9(1):1606
Dong Sun Oh, Ji Eun Oh, Hi Eun Jung, Heung Kyu Lee. Transient depletion of CD169+ cells contributes to impaired early protection and effector CD8+ T cell recruitment against mucosal respiratory syncytial virus infection. Frontiers in Immunology 2017;8:819
Dong Sun Oh, Heegon Kim, Ji Eun Oh, Hi Eun Jung, Yun Soo Lee, Ji-Ho Park, Heung Kyu Lee. Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses. Oncotarget 2017;8:47440-47453
Ji Eun Oh, Dong Sun Oh, Hi Eun Jung, Heung Kyu Lee. A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract. Proc Natl Acad Sci U S A 2017;114(7):E1188-E1195
Ji Eun Oh, Byoungchan Kim, Dong Ho Chang, Meehyang Kwon, Sun Young Lee, Dukjin Kang, Jin Young Kim, Inhwa Hwang, Je-Wook Yu, Susumu Nakae, Heung Kyu Lee. Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa. Proc Natl Acad Sci U S A 2016;113(6):E762-E771
Ji Eun Oh*, Myeong Sup Lee*, Young-Joon Kim, Heung Kyu Lee (*co-first author). OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production. Scientific Reports 2016;11:19089
Dong-Ho Chang, Moon-Soo Rhee, Sharon Ahn, Byung-Ho Bang, Ji Eun Oh, Heung Kyu Lee, Byoung-Chan Kim. Faecalibaculum rodentium gen. nov., sp. nov., isolated from the faeces of a laboratory mouse. Antonie van Leeuwenhoek 2015;108(6):1309-1318
Ji Eun Oh, Heung Kyu Lee. Pattern recognition receptors and autophagy. Frontiers in Immunology 2014;5:300
Ji Eun Oh, Heung Kyu Lee. Autophagy as an innate immune modulator. Immune Network 2013;13:1-9
Ji Eun Oh, Heung Kyu Lee. Modulation of pathogen recognition by autophagy. Frontiers in Immunology 2012;3:44
Ji Eun Oh, Heung Kyu Lee. Autophagy in innate recognition of pathogens and adaptive immunity. Yonsei Medical Journal 2012;53(2):241-247
Yeon Ju Hong, Ji Eun Oh, You Won Choi, Ki Bum Myung, Hae Young Choi. A Case of Clear Cell Eccrine Porocarcinoma. Annals of Dermatology 2010;22:330-332
Ji Eun Oh, You Won Choi, Ki Bum Myung, Hae Young Choi. Electron-microscopic Findings of Elastic Fibers in Zebrafish Skin. Korean Journal of Dermatology 2009;47:379-385
Ji-Eun Oh, Sang-Min Lee, Kyu-Kwang Whang. Two Cases of Annular Skin Defects Repaired with Quadruple Fan Flaps (O-X Flap). Annals of Dermatology 2009;21:102-105
Ji Eun Oh, You Won Choi, Hae Young Choi, Ki Bum Myung. A Case of Cellular Schwannoma of the Lower Lip. Korean Journal of Dermatology 2008;46:1282-1284
Ji Eun Oh, Ji Yeon Lim, So Young Kim, You Won Choi, Ki Bum Myung, Yun Ah Seong, Hae Young Choi. A Case of Hemochromatosis. Korean Journal of Dermatology 2008;46:937-940