Publications
Bookuan
1. Engineering Microbial Metabolism for Chemical Synthesis: Reviews and Perspectives. Edited by Yan, Y.*, World Scientific Publishing Europe Ltd. 2017
Book Chapters
3. Yang, Y., Wang, J., Zhang, R., Yan, Y.*, Antisense RNA Elements for Downregulating Expression in Microbial Metabolic Engineering. Springer. 2019
2. Wang, J., Yang, Y., Yan, Y.*, Bioproduction of Resveratrol. in Biotechnology of Natural Products. Springer. 2018
1. Wang, J., Yan, Y.*, Glycolysis and Its Metabolic Engineering Applications. in Engineering Microbial Metabolism for Chemical Synthesis: Reviews and Perspectives. World Scientific Publishing Europe Ltd. 2017
2024
117. Teng, Y., Jiang, T., Yan, Y.*, The expanded CRISPR toolbox for constructing microbial cell factories. Trends in Biotechnology 2024; 42: 104-118.
2023
116. Jiang, T., Teng, Y., Li, C., Gan, Q., Zhang, J., Zou, Y., Desai, B., Yan, Y.*, Establishing tunable genetic logic gates with versatile dynamic performance by varying regulatory parameters. ACS Synthetic Biology 2023; 12:3730-3742
115. Gong, X., Holmes, J., Li, Y., Liu, Z., Gan, Q., Wu, Z., Zhang, J., Zou, Y., Teng, Y., Jiang, T., Zhu, H., Liu, W.*, Liu, T.*, Yan, Y*. Evaluating the potential of leading large language model in reasoning biology questions. arXiv 2023.
114. Teng, Y., Wang, J., Jiang, T., Zou, Y., Yan, Y.*, Engineering a Streptococcus Cas9 ortholog with an RxQ PAM-binding motif for PAM-free gene control in bacteria. ACS Synthetic Biology 2023; 12: 2764-2772.
113. Jiang, T, Li, C., Teng, Y., Zhang, J., Logan, D., Yan, Y.*, Dynamic metabolic control: from the perspective of regulation logic. Synthetic Biology and Engineering 2023; 1-10012.
112. Li, C., Zhou, Y., Zou, Y., Jiang, T., Gong, X., Yan, Y.*, Identifying, characterizing, and engineering a phenolic acid-responsive transcriptional factor from Bacillus amyloliquefaciens. ACS Synthetic Biology 2023; 12:2382-2392.
111. Zhang, J., Gong, X., Gan, Q., Yan, Y.*, Application of metabolite-responsive biosensors for plant natural products biosynthesis. Biosensors 2023; 13: 633.
110. Zou, Y., Teng, Y., Li, J., Yan, Y.*, Recent advances in the biosynthesis of coumarin and its derivatives. Green Chemical Engineering 2023; In press.
109. Lu, L., Wang, X., Zhou, L., Liu, Q., Zhang, G., Xue, B., Hu, C., Shen, X., Sun, X., Shen, X., Yan, Y., Wang, J.*, Yuan, Q.*, Establishing biosynthetic pathway for the production of p-hydroxyacetophenone and its glucoside in Escherichia coli. Metabolic Engineering 2023; 76: 110-119.
108. An, N., Xie, C., Zhou, S., Wang, J., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Establishing a growth-coupled mechanism for high-yield production of β-arbutin from glycerol in Escherichia coli. Bioresource Technology 2023; 369: 128491.
107. Li, X., Li, N., Zhao, M., Zhou, Z., Li, W., Shen, X., Wang, J., Yan, Y., Sun, X.*, Yuan, Q.*, Engineering Escherichia coli native metabolism for efficient biosynthesis of orotate. Biotechnology and Bioengineering 2023; 120: 503-510.
106. Wang, J., Li, C., Jiang T., Yan, Y.*, Biosensor-assisted titratable CRISPRi high-throughput (BATCH) screening for over-production phenotypes. Metabolic Engineering 2023; 75: 58-67.
105. Wang, J., Teng, Y., Gong, X., Zhang, J., Wu, Y., Lou, L., Li, M., Xie, ZR., Yan, Y.*, Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria. Metabolic Engineering 2023; 75: 68-77.
2022
104. Li, W., Zhou, Z., Li, X., Ma, L., Quan, Q., Zheng, G., Liang, H., Yan, Y., Shen, X., Wang, J., Sun, X.*, Yuan, Q.*, Biosynthesis of plant hemostatic dencichine in Escherichia coli. Nature Communications 2022; 13: 5492.
103. Jiang, T., Li C., Zou, Y., Zhang, J., Gan, Q., Yan, Y.*, Establishing an Autonomous Cascaded Artificial Dynamic (AutoCAD) regulation system for improved pathway performance. Metabolic Engineering 2022; 74: 1-10.
102. Zhou, Z., Zhang, X., Wu, J., Li, X., Li, W., Sun, X., Wang, J., Yan, Y., Shen, X.*, Yuan, Q.*, Targeting cofactors regeneration in methylation and hydroxylation for high level production of ferulic acid. Metabolic Engineering 2022; 73: 247-255.
101. Gong, X., Zhang, R., Wang, J., Yan, Y.*, Engineering of a TrpR-based biosensor for altered dynamic range and ligand preference. ACS Synthetic Biology 2022; 11: 2175-2183.
100. Zhang, F., Sun, X., Shen, X., Yan, Y., Wang, J.*, Yuan, Q.*, Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase. Biotechnology and Bioengineering 2022; 119: 2518-2528.
99. Wang. J., Jiang, T., Milligan, S., Zhang, J., Li, C., Yan, Y.*, Improving isoprenol production via systematic CRISPRi screening in engineered Escherichia coli. Green Chemistry 2022; 24: 6955-6964.
98. Ge, C., Yu, Z., Sheng, H., Shen, X., Sun, X., Zhang, Y., Yan, Y., Wang, J.*, Yuan, Q.*, Redesigning regulatory components of quorum-sensing system for diverse metabolic control. Nature Communications 2022; 13: 1-12.
97. Li, X., Zhao, Z., Li, W., Yan, Y., Shen, X., Wang, J., Sun, X.*, Yuan, Q.*, Design of stable and self-regulated microbial consortia for chemical synthesis. Nature Communications 2022; 13: 1-9.
96. Lu, L., Shen, X., Sun, X., Yan, Y., Yuan, Q.*, Wang, J.*, CRISPR-based metabolic engineering in non-model microorganisms. Current Opinion in Biotechnology 2022; 75: 102698.
95. Teng, Y., Zhang, J., Jiang, T., Zou, Y., Gong, X., Yan, Y.*, Biosensor-enabled pathway optimization in metabolic engineering. Current Opinion in Biotechnology 2022; 75: 102696.
94. Li, C., Zou, Y., Jiang, T., Zhang, J., Yan, Y.*, Harnessing plasmid replication mechanism to enable dynamic control of gene copy in bacteria. Metabolic Engineering 2022; 70: 67-78.
93. Li, C., Jiang, T., Li, M., Zou, Y., Yan, Y.*, Fine-tuning gene expression for improved biosynthesis of natural products: from transcription to post-translational regulation. Biotechnology Advances 2022; 54: 107853.
2021
92. Wang, J., Teng, Y., Zhang, R., Wu, Y., Lou, L., Zou, Y., Li, M., Xie, ZR., Yan, Y.*, Engineering a PAM-flexible SpdCas9 variant as a universal gene repressor. Nature Communications 2021; 12: 1-10.
91. Wang, J., Zhang, R., Zhang, J., Gong, X., Jiang, T., Sun. X., Shen, X., Wang, J., Yuan, Q., Yan, Y.*, Tunable hybrid carbon metabolism coordination for carbon-efficient biosynthesis of 1,3-butanediol in Escherichia coli. Green Chemistry 2021; 23: 8694-8706.
90. Zhang, R., Wang, J., Milligan, S., Yan, Y.*, Microbial utilization of lignin-derived aromatics via a synthetic catechol meta-cleavage pathway. Green Chemistry 2021; 23: 8238-8250.
89. Shen, X., Chen X., Wang, J., Sun, X., Dong, S., Li, Y., Yan, Y., Wang, J.*, Yuan, Q.*, Design and construction of an artificial pathway for biosynthesis of acetaminophen in Escherichia coli. Metabolic Engineering 2021; 68: 26-33.
88. Zou, Y., Li, C., Zhang, R., Jiang, T., Liu, N., Wang, J., Wang, X., Yan, Y.*, Exploring the tunability and dynamic properties of MarR-PmarO sensor system in Escherichia coli. ACS Synthetic Biology 2021; 10: 2076-2086.
87. Ning, A., Chen, X., Sheng, H., Wang, J., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Rewiring the microbial metabolic network for efficient utilization of mixed carbon sources. Journal of Industrial Microbiology and Biotechnology 2021; 48: kuab040.
86. Zhang, R., Zhang, Y., Wang, J., Yang, Y., Yan, Y.*, Development of antisense RNA-mediated quantifiable inhibition for metabolic regulation. Metabolic Engineering Communications 2021; e00168.
85. Sheng, H., Jing, Y., Ning, A., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q.*, Extending the shikimate pathway for microbial production of maleate from glycerol in engineered E. coli. Biotechnology and Bioengineering 2021; 118: 1840-1850.
84. Li, Y., Shen, X., Sun, X., Yuan, Q., Yan, Y., Wang, J.*, Advances of CRISPR gene editing in microbial synthetic biology. Synthetic Biology Journal 2021; 2: 106.
83. Jiang, T., Li, C., Yan, Y.*, Optimization of a p-coumaric acid biosensor system for versatile dynamic performance. ACS Synthetic Biology 2021; 10: 132-144.
2020
82. Sheng, H., Sun, X., Yan, Y., Yuan, Q., Wang, J., Shen, X.*, Metabolic engineering of microorganisms for the production of flavonoids. Frontiers in Bioengineering and Biotechnology 2020, 8: 1162.
81. Wang, J., Li, C., Zou, Y., Yan, Y.*, Bacterial synthesis of C3-C5 diols via extending amino acid catabolism. Proceedings of the National Academy of Sciences 2020; 117: 19159-19167.
80. Jiang, T., Li, C., Teng, Y., Zhang, R., Yan, Y.*, Recent advances in improving metabolic Robustness of microbial cell factories. Current Opinion of Biotechnology 2020; 66: 69-77.
79. Wang, J., Zhang, R., Chen, X., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Biosynthesis of aromatic polyketides in microorganisms using type II polyketide synthases. Microbial Cell Factories 2020; 19: 1-11.
78. Zhou, Z., Chen, X., Sheng, H., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q.*, Engineering probiotics as living diagnostics and therapeutics for improving human health. Microbial Cell Factories 2020; 19: 1-12.
77. Ma, L., Guo, L., Yang, Y., Guo, K., Yan, Y., Ma, X., Huo, Y.*, Protein-based biorefining driven by nitrogen-responsive transcriptional machinery. Biotechnology for Biofuels 2020; 13: 1-14.
76. Ge, C., Sheng, H., Chen, X., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q*., Quorum sensing system used as a tool in metabolic engineering. Biotechnology Journal 2020; 15: 1900360.
75. Li, C., Zhang, R., Wang, J., Wilson, L., Yan, Y.*, Protein engineering for improving and diversifying natural products biosynthesis. Trends in Biotechnology 2020; 38: 729-744.
2019
74. Yu, H., Chen, Z., Wang, N., Yu, S., Yan, Y., Huo, YX*., Engineering transcription factor BmoR for screening butanol overproducers. Metabolic Engineering 2019; 56: 28-38.
73. Wang, J., Zhang, R., Zhang, Y., Yang, Y., Lin, Y., Yan, Y.*, Developing a pyruvate-driven scenario for growth-coupled microbial production. Metabolic Engineering 2019; 55: 191-200.
72. Li, W., Ma, L., Shen, X., Wang, J., Feng, Q., Liu, L., Zheng, G., Yan, Y., Sun, X.*, Yuan, Q.*, Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production. Nature Communications 2019; 10: 3337.
71. Zhang, R., Yang, Y., Wang, J., Lin, Y.*, Yan, Y.*, Synthetic symbiosis combining plasmid displacement enables rapid construction of phenotype-stable strains. Metabolic Engineering 2019; 55: 85-91.
70. Shen, X., Zhou, D., Lin, Y., Wang, J., Gao, S., Kandavelu, P., Zhang, H., Zhang, R., Wang, B-C., Rose, J.*, Yuan, Q.*, Yan, Y.*, Structural insight into catalytic versatility of the flavin-dependent hydroxylase (HpaB) from Escherichia coli. Scientific Reports 2019; 9: 7087.
69. .Shen, X., Wang, J., Li, C., Yuan, Q., Yan, Y.*, Dynamic gene expression engineering as a tool in pathway engineering. Current Opinion of Biotechnology 2019; 59: 122-129.
68. Li, X., Shen, X., Wang, J., Ri, H., Mi, C., Yan, Y., Sun, X.*, Yuan, Q.*, Efficient biosynthesis of 3,4- dihydroxyphenylacetic acid in Escherichia coli. Journal of Biotechnology 2019; 294: 14-18.
67. Li, Y., Wang, M., Zhao, Q., Shen, X., Wang, J., Yan, Y., Sun, X.*, Yuan, Q.*, Shunting phenylacetic acid catabolism for tropone biosynthesis. ACS Synthetic Biology 2019; 8: 876-883.
2018
66. Zhang, R., Li, C., Wang, J., Yan, Y.*, Microbial ligninolysis: towards a bottom-up approach for lignin upgrading. Biochemistry 2018; 58: 1501-1510.
65. Zhang, R., Li, C., Wang, J., Yang, Y., Yan, Y.*, Microbial production of small medicinal molecules and biologics: from nature to synthetic pathways. Biotechnology Advances 2018; 36: 2219-2231.
64. Huo, Y., Ren, H., Yu, H., Zhao, L., Yu, S., Yan, Y., Chen, Z., CipA-mediating enzyme self-assembly to enhance the biosynthesis of pyrogallol in Escherichia coli. Applied Microbiology and Biotechnology 2018; 1-11.
63. Yang, Y., Lin, Y., Wang, J., Wu, Y., Zhang, R., Chen, M., Shen, X., Wang, J., Chen, Z., Yuan, Q., Yan, Y.*, Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis. Nature Communications 2018; 9: 3043.
62. Wang, J., Shen, X., Wang, J., Yang, Y., Yuan, Q.*, Yan, Y.*, Exploring the promiscuity of phenol hydroxylase from Pseudomonas stutzeri OX1 for the biosynthesis of phenolic compounds. ACS Synthetic Biology 2018; 7: 1238-1243.
61. Shen, X, Wang, J., Gall, B., Ferreira, E., Yuan, Q.*, Yan, Y.*, Establishment of novel biosynthetic pathways for the production of salicyl alcohol and gentisyl alcohol in engineered Escherichia coli. ACS Synthetic Biology 2018; 7: 1012-1017.
60. LYU, Z., Chou, CW., Shi, H., Wang, L., Ghebreab, R., Phillips, D., Yan, Y., Duin, E., William, W., Assembly of methyl-coenzyme M reductase in the methanogenic archaeon Methanococcus maripaludis. Journal of Bacteriology 2018; JB. 00746-17.
59. Sekar, N., Wang, J., Zhou, Y., Fang, Y., Yan, Y., Ramasamy, R., Role of Respiratory Terminal Oxidases in the Extracellular Electron Transfer Ability of Cyanobacteria. Biotechnology and Bioengineering 2018; 115: 1361-1366.
58. Wang, J., Shen, X., Yuan, Q.*, Yan, Y*. Microbial synthesis of pyrogallol using genetically engineered Escherichia coli. Metabolic Engineering 2018; 45:134-141.
57. Wu, Y., Wang, J., Shen, X., Wang, J., Chen, Z., Sun, X., Yuan, Q.*, Yan, Y.*, Investigating the strategies for microbial production of trehalose from lignocellulosic sugars. Biotechnology and Bioengineering 2018; 115: 785-790.
56. Li, X., Chen, Z., Wu, Y., Yan, Y., Sun, X., Yuan, Q., Establishing an artificial pathway for efficient biosynthesis of hydroxytyrosol. ACS Synthetic Biology 2018; 7: 647-654.
55. Wang, J., Shen, X., Lin, Y., Chen, Z., Yang, Y., Yuan, Q.*, Yan, Y.*, Investigation of the synergetic effect of xylose metabolic pathways on the production of glutaric acid. ACS Synthetic Biology 2018; 7: 24-29.
54. Wang, J., Shen, X., Rey, J., Yuan, Q.*, Yan, Y.*, Recent Advances in Microbial Production of Aromatic Compounds and Their Derivatives. Applied Microbiology and Biotechnology 2018; 1: 47-61.
53. Wang, J., Yang, Y., Zhang, R., Shen, X., Chen, Z., Yuan, Q.*, Yan, Y.*, Microbial production of branched-chain dicarboxylate 2-methylsuccinic acid via enoate reductase- mediated bioreduction. Metabolic Engineering 2018; 45: 1-10.
2017
52. Wang, J., Mahajani, M., Jackson, S., Yang, Y., Chen, M., Ferreira, E., Lin, Y., Yan, Y.*, Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides. Metabolic Engineering 2017; 44: 89-99.
51. Tian, P., Wang, J., Shen, X., Justin, R., Yuan, Q., Yan, Y.*, Fundamental CRISPR-Cas9 Tools and Current Applications in Microbial Systems. Synthetic and Systems Biotechnology 2017; 2: 219-225.
50. Wang, J., Wu, Y., Sun, X., Yuan, Q.*, Yan, Y.*, De novo Biosynthesis of Glutarate via a-Keto Acid Carbon Chain Extension and Decarboxylation Pathway in Escherichia coli. ACS Synthetic Biology 2017; 6: 1922-1930.
49. Chen, Z., Shen, X., Wang, J., Wang, J., Yuan, Q.*, Yan, Y.*, Rational Engineering of p-Hydroxybenzoate Hydroxylase to Enable Efficient Gallic Acid Synthesis via A Novel Artifical Biosynthetic Pathway. Biotechnology and Bioengineering 2017; 114: 2571-2580.
48. Chen, Z., Shen, X., Wang, J., Wang, J., Zhang, R., Rey, J., Yuan, Q.*, Yan, Y.*, Establishing an Artificial Pathway for De novo Biosynthesis of Vanillyl Alcohol in Escherichia coli. ACS Synthetic Biology 2017; 6: 1784-1792.
47. Shen, X., Mahajani, M., Wang, J., Yang, Y., Yuan, Q., Yan, Y.*, Lin, Y.*, Elevating 4-Hydroxycoumarin Production through Alleviating Thioesterase-mediated Salicoyl-CoA Degradation. Metabolic Engineering 2017; 42: 59-65.
46. Shen X., Wang, J., Wang, J., Chen, Z., Yuan, Q.*, Yan, Y.*, High-level De novo Biosynthesis of Arbutin in Engineered Escherichia coli. Metabolic Engineering 2017; 42: 52- 58.
45. Wang, J., Shen, X., Rachit, J., Wang, J., Yuan, Q.*, Yan, Y.*, Establishing A Novel Biosynthetic Pathway for the Production of 3,4-Dihydroxybutyric Acid from Xylose in Escherichia coli. Metabolic Engineering 2017; 41: 39-45.
44. Cowger, T., Yang, Y., Rink, D., Todd, T., Chen, H.*, Shen, Y., Yan, Y.*, Xie, J., Protein-Adsorbed Magnetic-Nanoparticle-Mediated Assay for Rapid Detection of Bacterial Antibiotic Resistance. Bioconjugate Chemistry 2017; 28: 890-896.
43. Wang, J., Jain, R., Shen, X., Sun, X., Cheng, M., Liao, J.C., Yuan, Q.*, & Yan, Y.*, Rational Engineering of Diol Dehydratase Enables 1,4-Butanediol Biosynthesis from Xylose. Metabolic Engineering 2017; 40: 148-156.
42. Chen, Z., Sun, X., Li, Y., Yan, Y., & Yuan, Q.*, Metabolic Engineering of Escherichia coli for Microbial Synthesis of Monolignols. Metabolic Engineering 2017; 39:102-109.
41. Wu, Y., Sun, X., Lin, Y., Shen, X., Yang, Y., Jain, R., Yuan, Q.*, & Yan, Y.*, Establishing a Synergetic Carbon Utilization Mechanism for Non-catabolic Use of Glucose in Microbial Synthesis of Trehalose. Metabolic Engineering 2017; 39:1-8.
2016
40.Lyu, Z., Jain, R., Smith, P., Fetchko, T., Yan, Y., & Whitman, W.*, Engineering the Autotroph Methanococcus maripaludis for Geraniol Production. ACS Synthetic Biology 2016; 5:577-581.
39. Sun, J., Lin, Y., Shen, X., Jain, R., Sun, X., Yuan, Q.*, & Yan, Y.*, Aerobic Biosynthesis of Hydrocinnamic Acids in Escherichia coli with A Strictly Oxygen-sensitive Enoate Reductase. Metabolic Engineering 2016; 35:75-82.
38. Wu, Y., Shen, X., Yuan, Q.*, & Yan,Y.*, Metabolic Engineering Strategies for Co-utilization of Carbon Sources in Microbes. Bioengineering 2016; 3:10.
37. Wang, J., Guleria, S., Koffas, M. A.*, & Yan, Y.*, Microbial Production of Value-added Nutraceuticals. Current Opinion in Biotechnology 2016; 37: 97-104.
36. Sekar, N., Rachit, J., Yan, Y., & Ramasamy, R.*, Enhanced Photo-bioeletrochemical Energy Conversion by Genetically Engineered Cyanobacteria. Biotechnology & Bioengineering 2016; 113:675-9.
2015
35. Sun, X., Shen, X., Jain, R., Lin, Y., Wang, J., Sun, J., Wang, J., Yan, Y.*, & Yuan, Q.*, Synthesis of Chemicals by Metabolic Engineering of Microbes. Chemical Society Reviews 2015; 44:3760-85.
34. Jain, R., Huang, Q., Yuan, Q., & Yan, Y.*, Engineering Microaerobic Metabolism of E. coli for 1,2-Propanediol Production. Journal of Industrial Microbiology & Biotechnology 2015; 42:1049-55.
33. Zhang, T., Wang, Z., Deng, L., Tan, T., Wang, F., & Yan, Y., Pull-in Urea Cycle for the Production of Fumaric Acid in Escherichia coli. Applied Microbiology and Biotechnology 2015; 99:5033-44.
32. Sun, X., Zhou, D., Kandavelu, P., Zhang, H., Yuan, Q., Wang, BC., Rose, J.*, & Yan, Y.*, Structural Insights into Substrate Specificity of Feruloyl-CoA 6'-Hydroxylase fromArabidopsis thaliana. Scientific Reports 2015; 5:10355.
31. Yang, Y., Lin, Y., Li, L., Linhardt, R., & Yan, Y.*, Regulating Malonyl-CoA Metabolism via Synthetic Antisense RNAs for Enhanced Biosynthesis of Natural Products.Metabolic Engineering 2015; 29:217-26.
30. Huang, J., Lin, Y., Yuan, Q., & Yan, Y.*, Production of tyrosine through phenylalanine hydroxylation bypasses the intrinsic feedback inhibition in Escherichia coli. Journal of Industrial Microbiology & Biotechnology 2015; 42:655-9.
29. Jain, R., Sun, X., Yuan, Q., & Yan, Y.*, Systematically Engineering Escherichia coli for Enhanced Production of 1,2-Propanediol and 1-Propanol. ACS Synthetic Biology 2015; 4:746-56.
28. Sun, X., Lin, Y., Yuan, Q.*, & Yan, Y.*, Precursor-directed biosynthesis of 5-hydroxytryptophan using metabolically engineered E. coli. ACS synthetic Biology 2015; 4:554-8.
2014
27. Lin, Y., Sun. X., Yuan, Q., & Yan, Y.*, Engineering Bacterial Phenylalanine 4-Hydroxylase for Microbial Synthesis of Human Neurotransmitter Precursor 5- Hydroxytryptophan. ACS Synthetic Biology 2014; 3:497-505.
26. Sun, X., Lin, Y., Yuan, Q., & Yan, Y.*, Biological Production of Muconic Acid via A Prokaryotic 2,3-Dihydroxybenzoic Acid Decarboxylase. ChemSusChem 2014; 7:2478-81.
25. Lin, Y., & Yan, Y.*, Biotechnological Production of Plant-Specific Hydroxylated Phenylpropanoids. Biotechnology and Bioengineering 2014; 111:1895-9.
24. Lin, Y., Sun, X., Yuan, Q., & Yan, Y.*, Extending Shikimate Pathway for the Production of Muconic Acid and Its Precursor Salicylic Acid in Escherichia coli. Metabolic Engineering 2014; 23:62-9.
23. Lin, Y., Jain, R., & Yan, Y.*, Microbial production of antioxidant food ingredients via metabolic engineering. Current Opinion of Biotechnology 2014; 26:71-78.
2013
22. Lin, Y., Shen, X., Yuan, Q., & Yan, Y.*, Microbial biosynthesis of the anticoagulant precursor 4-hydroxycoumarin. Nature Communications 2013; 4:2603.
21. Huang, Q., Lin, Y., & Yan, Y.*, Caffeic acid production enhancement by engineering a phenylalanine over-producing Escherichia coli strain. Biotechnology and Bioengineering 2013; 110:3188-96.
20. Lin, Y., Sun, X., Yuan, Q., & Yan, Y.*, Combinatorial biosynthesis of plant-specific coumarins in bacteria. Metabolic Engineering 2013; 18:69-77.
19. Sun, X., Lin, Y., Huang, Q., Yuan, Q., & Yan, Y.*, A novel muconic acid biosynthesis approach by shunting tryptophan biosynthesis via anthranilate. Applied and Environmental Microbiology 2013; 79:4024-30.
2012
18. Shen, X., Lin, Y., Jain, R., Yuan, Q., & Yan, Y.*, Inhibition of acetate accumulation leads to enhanced production of (R,R)-2,3-butanediol in Escherichia coli. Journal of Industrial Microbiology & Biotechnology 2012; 39: 1725-1729.
17. Subramanian, S., Shen, X., Yuan, Q., & Yan, Y.*, Identification and biochemical characterization of a 5-DMATS in Streptomyces coelicolor A3(2). Process Biochemistry 2012; 47: 1419-1422.
16. Lin, Y., & Yan, Y.*, Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase. Microbial Cell Factories 2012; 11: 42.
2011
15. Jain, R.,& Yan, Y.*, Dehydratase mediated 1-propanol production in metabolically engineered Escherichia coli. Microbial Cell Factories 2011; 10: 97.
14. Huo, Y., Cho, K. M., Rivera, J.G. L., Monte, E., Shen, C., Yan, Y., & Liao, J.C., Conversion of proteins into biofuels by engineering nitrogen flux. Nature Biotechnology 2011; 29: 346-351.
Publications Prior to UGA
13. Yan, Y., & Liao, J.C., Enantioselective synthesis of pure (R,R)-2,3-butanediol in Escherichia coli with stereospecific secondary alcohol dehydrogenases. Organic&Biomolecular Chemistry 2009, 7:3914-3917.
12. Yan, Y., & Liao, J.C., Engineering metabolic systems for production of advanced fuels. Journal of Industrial Microbiology and Biotechnology 2009; 36(4): 471-9.
11. Leonard, E., Yan, Y., Fowler, Z.L., Li, Z., Lim, C.G., Lim, K.H., Koffas, M.A., Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids. Molecular Pharmaceutics 2008; 5(2):257-65.
10. Yan, Y., Li, Z., & Koffas, M.A., High-yield anthocyanin biosynthesis in engineered Escherichia coli. Biotechnology and Bioengineering 2008; 100(1): 126-40.
9. Leonard, E., Yan, Y., Chemler J.A., Matern U., Martens S. & Koffas M.A., Characterization of dihydroflavonol 4-reductases for recombinant plant pigment biosynthesis applications. Biocatalysis and Biotransformation 2008; 26(3): 243-51.
8. Chemler, J.A., Yan, Y., Leonard, E. & Koffas M.A., Combinatorial mutasynthesis of flavonoid analogues from acrylic acid in microorganisms. Organic Letter 2007; 9(10):1855- 8.
7. Yan, Y., Huang L., & Koffas, M.A., Biosynthesis of 5-deoxyflavanones in microorganisms. Biotechnology Journal 2007; 2(10): 1250-62.
6. Chemler, J. A., Yan, Y. & Koffas, M.A., Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. Microbial Cell Factories 2006; 5:20. (First two authors contributed equally)
5. Leonard, E., Yan, Y. & Koffas, M.A., Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli. Metabolic Engineering 2006; 8(2):172-81.
4. Leonard, E., Yan, Y., Lim, K.H. & Koffas, M.A., Investigation of two distinct flavone synthases for plant-specific flavone biosynthesis in Saccharomyces cerevisiae. Applied and Environmental Microbiology 2005; 71(12):8241-8.
3. Yan, Y., Kohli, A. & Koffas, M.A., Biosynthesis of natural flavanones in Saccharomyces cerevisiae. Applied and Environmental Microbiology 2005; 71(9):5610-3.
2. Yan, Y., Chemler, J., Huang, L., Martens, S. & Koffas, M.A., Metabolic engineering of anthocyanin biosynthesis in Escherichia coli. Applied and Environmental Microbiology 2005;71(7):3617-23.
1. Yan, Y., Chen, J. & Li, J., Overexpression of a small medicinal peptide from ginseng in the yeast Pichia pastoris. Protein Expression and Purification 2003; 29(2):161-6.