Professor
Professor
Dr. Sung Kuk Lee
이성국
Researcher Profile / Google Scholar
E-mail : sklee-at-unist-dot-ac-dot-kr
Professor office telephone : 052-217-2514
Lab. telephone : 052-217-2574
Student office telephone : 052-217-2599
School address : UNIST-gil 50, Ulju-gun, Ulsan 44919, Republic of Korea
Professor office : Engineering Building 2 (Bldg. 104) Rm. 401-2
Laboratory : Engineering Building 2 (Bldg. 104) Rm. 407/408 (Synthetic Biology Lab.)
Ulsan National Institute of Science and Technology (UNIST)
School of Energy & Chemical Engineering (ECHE), Department of Chemical Engineering (화학공학), Department of Energy Engineering (에너지공학과),
Department of Biomedical Engineering (생명공학)
Education :
Ph.D. School of Environmental Science and Engineering, Pohang University of Science and Technology (POSTECH), Korea, 2001
M.S. Department of Life Science, POSTECH, Korea, 1997
B.S. Department of Microbiology, Kyungbook National University, Korea, 1994
Work experiences :
Professor, School of Energy & Chemical Engineering (ECHEN), UNIST, 2020.09 - present
Visiting faculty, UC-Berkeley/ JBEI, 2015/2 - 2016/2
Associate professor, School of Energy & Chemical Engineering (ECHEN), UNIST, 2013.09 - 2020.08
Assistant professor, School of Nano-Bioscience & Chemical Engineering (NBC), UNIST, 2008.12 - 2013.08
Co-Director, Fuel Synthesis Division, Joint BioEnergy Institute (JBEI)/Lawrence Berkeley National Laboratory (LBNL), 2007/12 – 2008/11
Associate Specialist II, Department of Chemical Engineering, UC Berkeley and Synthetic Biology Department, SynBERC/LBNL, 2004/12 – 2007/11
Postdoctoral Fellow, Department of Chemical Engineering, UC Berkeley, 2001/11 – 2004/11
Postdoctoral Fellow, Department of Chemical Engineering, POSTECH, 2001/9 – 2001/11
Memberships :
Committee Member, The Korean Society for Biotechnology and Bioengineering (KSBB, 한국생물공학회)
Committee Member, The Korean Society for Microbiology and Biotechnology (KMB, 한국미생물생명공학회)
Committee Member, The Microbiological Society of Korea (MSK, 한국미생물학회)
Founder Member, The Korean Society for Synthetic Biology (한국합성생물학회)
Journal Editor :
Editorial Board (편집위원), KSBB (한국생물공학회); Biotechnology and Bioprocess Engineering (2022. 01 ~ )
Editorial Board (편집위원), KMB (한국미생물.생명공학회); Journal of Microbiology and Biotechnology (2016. 01 ~ )
Editorial Board (편집위원), MSK (한국미생물학회), Journal of Microbiology (2012. 10 ~ 2017. 12 )
Editorial Board (편집위원), KSBB (한국생물공학회) KSBB Journal (2011. 03 ~ not present)
Editorial Board (편집위원), 한국생물공학회소식지 (BT News) (2011.02 ~ 2012.03)
Honors :
Sung Kuk Lee, The 2022 BBE Best Article Award from Biotechnology and Bioprocess Engineering (September 30, 2022)
Sung Kuk Lee, The 2021 BBE Best Article Award from Biotechnology and Bioprocess Engineering (October 07, 2021)
2013 제14회 LG 생명공학 경시대회 동상 수상 (지도학생: 최배영)
2012 URP 장려상 수상
Sung Kuk Lee, Dr. Lee was introduced as a main author on synthetic biology in PLos One (April 23, 2012)
Sung Kuk Lee, The 2012 BBE's Best Paper Award from Biotechnology and Bioprocess Engineering (September 20, 2012)
Sung Kuk Lee, The paper published in "Journal of Biological Engineering" was selected as one of highly accessed papers. (STaek S Lee, Rachel A Krupa, Fuzhong Zhang, Meghdad Hajimorad, William J Holtz, Nilu Prasad, Sung Kuk Lee and Jay D Keasling*. 09/20/2011. BglBrick vectors and datasheets: A synthetic biology platform for gene expression. Journal of Biological Engineering 5:12. [Open Link] )
Silver medal in 2011 iGEM regional competition at Hong Kong (October 15-16, 2011)
Sung Kuk Lee, The paper published in "Current Opinion in Biotechnology" was selected as one of the most cited articles published since 2008. (Sung Kuk Lee, Howard Chou, Timothy Ham, Taek Soon Lee, and Jay D. Keasling. 12/01/2008. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels. Current Opinion in Biotechnology 19:556-563. [Open Link] )
Professional Activities :
한국생물공학회, 국제협력 공동위원장, Co-Director of International Exchange (2024. 01. 01 ~ )
한국미생물생명공학회-영남 지부, 부회장 (2023. 01. 01 ~)
연구재단 전문위원, Reviewers Board member for National Research Foundation of Korea, Ministry of Science and ICT (MSIT), South Korea (2019. 11. 01 ~ 2022. 08. 31)
한국미생물생명공학회-영남지부, 총무간사 (2020. 03 - 2021. 02)
사단법인 농업미생물사업단, 전문위원 (2020. 01. 01 ~ )
Poster Evaluation Committee member, NHBT-2019, International conference on new horizons in biotechnology, Trivandrum, Kerala, India (2019. 11. 20 ~ 2019. 11. 23)
한국미생물학회-학술위원회 실무위원 (2019)
Session organizer (session title: Current advances in host cell engineering) in 2019 46th Annual Meeting & International Symposium, The Korean Society for Microbiology and Biotechnology (June 23~25, 2019, Jeju, Korea)
한국미생물생명공학회-생물공학 학술분과 위원장 (2019 ~ 2020 )
미세플라스틱 통합 관리 R&D, 다부처 사업 기획위원 (2019)
총괄연구책임자, 바이오산업핵심기술개발사업 (산업통상자원부-한국산업기술평가관리원): 300 L 생물반응기 규모 바이오 감마락톤 생산기술 개발 (A 300 L pilot-scale biological production of gamma-lactones) [2017. 07. 01 -- 2019. 12. 31]
KRIBB BIOREFINERY R&D 컨소시엄 외부 전문가 (2013.12.13 ~ )
울산 산학연관협의회 기술개발분과 위원 (2009. 05. 06 ~ )
울산 테크노산단 바이오화학 위원회 위원 (2009. 04. 29 ~ )
범부처 신재생 R&D 전문가 (교과부-바이오분야) (2011. 03 ~ )
전북도청/생명연 (정읍) 미생물융합기술기반 바이오매스 종합활용사업 기획위원 (2010. 06. 04. ~)
울산 바이오화학실용화센터 추진단 전문가 (2010. 04. 29. ~ )
한국미생물생명공학회-생물공학융합기술학술분과-산학협력간사 (2009 ~ 2017)
Session Chair, 2015/11/06, [생물공학] 바이오화학 생산기술의 최신동향, 한국 공업화학회, 제주, Korea. (June 4-6)
Session Chair, New Trends in Bioimaging Technology, KMB's Anniversary 2014 International Symposium & Annual meeting, Busan, Korea. (June 25-27)
Poster Evaluation Committee member, 2013 International Symposium. The Korean Society for Microbiology and Biotechnology, Alpensia Pyeongchang, Korea. (July 3-5)
Session Chair, Young Scientist Presentation, KMB's 40th Anniversary 2013 International Symposium & Annual meeting, Alpensia Pyeongchang, Korea. (July 3-5)
차세대 해양생명공학사업 추진위원 (2012.12 ~ 2013.11)
총괄연구책임자, 교과부 기후변화대응 기초•원천기술개발사업, 바이오에너지 연구단장 (2009.09.30 ~ 2015.09.29)
Session Chair, Metabolic Engineering for Biofuel and Biochemicals I, 2012 15th International Biotechnology Symposium (IBS), September 16-18-21, Daegu, Republic of Korea
Poster Evaluation Committee member, 2011 International Symposium. The Korean Society for Microbiology and Biotechnology, Kyungju, Korea (2011. 06. 22~24)
Local Committee Member in the 8th international Metabolic Engineering Conference (2010.06.13.~ 2010.06.17.)
교과부 글로벌프론티어사업 사전기획위원 (2010. 06. 04. ~ 2010. 06. 18.)
UNIST Activities :
생물안전위원회 위원 (2014.09.29 ~ 현재)
학술정보관 운영위원회 위원 (2019.03.01 ~ 2021. 02. 30)
교수평의회 의원 ( 2012.02 - 2012. 12)
MS/PhD THESES ADVISED :
Hyo Seok Ha, 02/2021
Hyun Wook Jung, 02/2021 "Multidimensional metabolic engineering and fermentation optimization for high-level production of free fatty acids in Escherichia coli" MS THESIS
Sun Ho Choi, 08/2020 "Promoter engineering enables control of glucose-responsive gene expression by using a transcriptional regulator HexR" MS THESIS
Yong Joo Lee, 02/2020 "Development of an inaA promoter-based biosensor for NDAEE overproduction in Escherichia coli " MS THESIS
Daegeun Cha, 02/2020 "Engineering of Pseudomonas putida for the production of various scl-PHAs from levulinic acid" MS THESIS
Ye-Eun Kim, 07/2019 "Engineering Escherichia coli to exploit alternative glycolytic pathways upon complete loss of the upper Embden-Meyerhof-Parnas pathway" MS THESIS
Geun Hwa Kwak, 08/2018 "Engineering of Escherichia coli for the production of azelaic Acid from nonanoic acid" MS THESIS
Hyun Ji Rho, 08/2018 "Construction and improvement of 2,4-dinitrotoluene-inducible biosensor in Escherichia coli" MS THESIS
Chang hee Kim, 02/2018 "An engineered E. coli with EDP enhancement, PPP cyclization and FadR overexpression to increase medium chain fatty acid synthesis" MS THESIS
Kwangsu Shin, 02/2018 "Engineering Escherichia coli to increase the production of free fatty acids" PhD THESIS
Kyungchul Kim, 02/2017, "Isolation and characterization of bacterial strains from explosive-contaminated soil" MS THESIS
Jonghoon Bae, 02/2017, "Production of D-lactate utilizing multiple sugars derived from biomass by engineered E. coli" MS THESIS
Taehwan Ham, 08/2015, "Production of hexanoic acid from long chain fatty acid in Escherichia coli" MS THESIS
Vinuselvi Parisutham, 02/2015, "Deciphering the molecular underpinnings of the cryptic cellobiose metabolism in Escherichia coli" PhD THESIS
Junyeong Lee, 02/2015, "Engineering Escherichia coli for effective expression of plant genes" MS THESIS
Ji Won Lim, 02/2014, "Fluid patterning in a cavity array for high-throughput screening and biotechnological applications" MS THESIS
Seong Hun Jeong, 11/30/2013, "Construction of a novel recombinant Escherichia coli strain capable of simultaneously utilizing glucose and xylose" MS THESIS
Jung Min Park, 02/2012, "Understanding and elimination of carbon catabolite repression in Escherichia coli" - MS THESIS
Jae Myung Lee, 08/2011, "Development of a light-switchable gene expression system in Escherichia coli" - MS THESIS
Invited Talks :
From Hot Spring to Green Chemistry: The Potential of Cupriavidus cauae PHS1 for Biorefineries. 2024/09/08~10. SBJ, Tokyo Institute of Technology, Ookayama Campus
Exploring Cupriavidus cauae PHS1: A Thermotolerant Biorefinery Platform. 06/19/2024 ~ 06/21/2024. International Symposium. The Korean Society for Microbiology and Biotechnology, Busan, Korea
Cupriavidus cauae PHS1: A Promising Thermotolerant Mircroorganism for Biopolymer Production and Diverse Application. 11/27/2023, NHBT-2023, International conference on new horizons in biotechnology, Trivandrum, Kerala, India [Plenary Lecture]
Maximizing MeFDH Expression Using Synthetic Biology Strategies: Possibilities and Limitations. 11/17/2023, 한국과총-부울경지부, Ulsan, Korea
Challenges and Opportunities in Levulinic Acid Biorefineries Utilzing Cellulosic Biomass, 섬유소 바이오매스를 활용한 레불린산 바이오리파이너리의 도전과 기회. 11/09/2023, KSMB 2023년 한국해양바이오학회
Cupriavidus cauae PHS1: Unlocking the Potential of a Thermotolerant Microorganism for Biorefinery Applications. 11/07/2023, 포항공대, I-Bio 정기세미나
Cupriavidus cauae PHS1: A Promising Thermotolerant Microorganism for Biorefinery. 10/06/2023, 2023 KSBB Fall Meeting and International Symposium, The Korean Society for Biotechnology and Bioengineering, Busan, Korea (Oct. 04 ~ 07)
맞춤형 인공미생물 제작을 위한 합성생물학/대사공학 기술. 02/16/2023, 경상대학교
고온성 미생물 Cupriavidus sp. PHS1 활용 바이오리파이너리. 11/08/2022, 한국과총-부울경지부, Ulsan, Korea
Biosynthesis of Polyhydroxylalkanoates (PHAs) by a thermotolerant Cupriavidus sp. PHS1 using Various Carbon Sources. IBA-IFIBiop, 10th International Forum on Industrial Bioprecesses (October 27, 28~30), Kaohsiung, Taiwan (On-line presentation)
Levulinic acid biorefineries: An alternative for efficient utilization of biomass. International Meeting of The Korean Society of Life Science, Gyeongju, Republic of Korea (August 11~12), 2022
바이오리파이너리를 위한 합성생물학과 대사공학. 07/28/2022, 한국 농업진흥청 (전주)
Gene expression systems in Pseudomonas putida: an alternative microbial cell factory for production of platform chemicals. 10/08/2021, 2021 KSBB Fall Meeting and International Symposium, The Korean Society for Biotechnology and Bioengineering, Gyeongju, Korea (Oct. 06 ~ 09)
Activation of Entner-Doudoroff pathway in Escherichia coli for high 3-HP production. 10/23/2020, 2020 KSBB Fall Meeting and International Symposium, The Korean Society for Biotechnology and Bioengineering, Seoul, Korea (Oct. 21 ~ 23)
Pseudomonas putida : an alternative microbial cell factory for production of platform chemicals. 11/21/2019, NHBT-2019, International conference on new horizons in biotechnology, Trivandrum, Kerala, India
Development of an engineered Escherichia coli platform strain for high NADPH-demanding 3-HP production. 11/08/2019, iBioT-2019, The 10th symposium on innovative bioproduction Taichung, Tunghai University, Taichung, Taiwan [Keynote Speech]
Engineering of glycolytic pathways in Escherichia coli for high NADPH-demanding 3-HP production. 11/04/2019, 한국과총-부울경지부, Ulsan, Korea
Engineering of glycolytic pathways in Escherichia coli for bio-production. 09/25/2019, International workshop on marine environmental microbes and chemical ecology, Tianjin University, Tianjin, China
Characterization of an Embden-Meyerhof-Parnas pathway-inactivated Escherichia coli. 08/22/2019, 미생물생명공학회-호남지부, 여수, Korea [Keynote Talk]
Metabolic engineering of sugar metabolism for biorefinery : redox and energy balance. 06/11/2019, 고려대학교 생명공학부, Seoul, Korea
Metabolic engineering of central metabolic pathways for biorefinery : redox and energy balance. 05/08/2019, 연세대 화학공학과, Seoul, Korea
Development of genetically engineered Escherichia coli for the detection of TNT and DNT. 11/15/2018, 한국화생방어학회, Gyeongju, Korea (11/15 ~ 11/16)
Biological production of gama-valerolactone from levulinic acid. 11//2/2018, The Korean society of Industrial and Engineering Chemistry, Jeju, Korea (10/31 ~ 11/2)
Production of fatty acids and their derivatives by metabolically engineered E. coli. 10/11/2018, The Korean Society for Biotechnology and Bioengineering, Seoul, Korea (Oct. 10 ~ 12)
미래 바이오 산업의 핵: 대사공학/합성생물학. 05/08/2018, 포항공대 생명과학과 학부 수업 강의, Pohang, Korea
Biological production of fatty acids and their derivatives. 11/10/2017, The Korean society of Industrial and Engineering Chemistry, Jeju, Korea (Nov. 8~10)
Construction of cellulose-derived sugars-utilizing Escherichia coli. 05/16/2017, 신재생에너지학회 (Korean Society for New and Renewable Energy), Jeju, Korea (May 15~17)
바이오리파이너리용 인공미생물 제작 및 활용. 06/15/2016, 울산바이오화학실용화센터, Ulsan, Korea
Targeted genome editing using a dual selection marker tetA in Escherichia coli. 04/22/2016, The Korean Society for Biotechnology and Bioengineering, Gyeongju, Korea (April 20 ~ 22)
A simple proficient method for targeted genome editing in Escherichia coli. 11/06/2015, The Korean society of Industrial and Engineering Chemistry, Jeju, Korea (Nov. 4~6)
Genome engineering in Escherichia coli. 06/11/2015, POSTECH, School of Interdisciplinary Bioscience and Bioengineering, Pohang, Korea
Genome engineering and its applications in Eshcherichia coli. 06/01/2015, Korea University, Department of Biotechnology, Seoul, Korea
Simple proficient methods for targeted genome editing. 05/26/2015, Gyeongsang National University, Systems & Synthetic Agrobiotech Center, Jinju, Korea
Development of genome editing methods for metabolic engineering in Escherichia coli. 05/07/2015, CJ Cheiljedang/Research Center for Bioproducts, Seoul, Korea
MAGE-based genome editing methods for metabolic engineering. 05/06/2015, KAIST, Department of Biological Sciences, Daejeon, Korea
MAGE-based genome editing and its applications in Escherichia coli, 04/15/2015, Joint BioEnergy Institute (JBEI), Emeryville, CA
인공미생물을 이용한 바이오리파이너리, 10/22/2014, 백광산업, 군산, Korea
인공미생물을 이용한 바이오리파이너리, 10/08/2014, 2014 한국화학공학회 울산지부 산학공 협동 세미나, 울산, Korea
Principle of metabolic pathway engineering: redox balance, 8/25 ~ 8/26/2014, 제70회 생물화공심포지움, 한국생물공학회, 거제, Korea
Biofuel production using synthetic microorganisms, 2/21~22/2014, 한국미생물-생명공학회 영남지부 학술대회, Gyeongju, Korea
Understanding of molecular-level mechanism involved in cellobiose and xylose co-metabolism of an engineered E. coli strain. 10/25/2013. 경희대학교, 유전공학과, 생명공학원
바이오 에너지 연구현황. 6/27~28/2013. 2013 기후변화대응기술 포럼. 미래창조과학부, 한국연구재단, 부산 해운대
Development of synthetic global regulatory systems in microbes for the utilization of plant genetic material. 05/21/2013. 국립농업과학원 생물소재공학과 초청세미나, 수원
The Intersection of Synthetic Biology and Medical Biotechnology. 05/14/2013. 경북대학교,의과대학, Daegu, Korea
Elucidation of the role of a novel transcription factor SK01. 05/02/2013. International Meeting of the Microbiological Society of Korea, Jeonju, Korea
인류와 지구를 구할 지능형 인공 생명체. 04/05/2013. 금요일에 과학터치, 대구광역시립중앙도서관, Daegu, Korea
Synthetic re-evaluation of the hidden cellobiolytic ability of E. coli. 12/18/2012. School of Chemical and Biomolecular Engineering, Pusan Natl. Univ., Pusan, Korea
Metabolic engineering of Escherichia coli for the efficient utilization of multiple sugars. 11/20/2012. POSTECH 환경공학부 세미나, Pohang, Korea
Metabolic engineering Escherichia coli capable of metabolizing multiple sugars. International Meeting of The Korean Society of Life Science, Daegu, Republic of Korea (October 25-26), 2012
Towards increasing the substrate utilization range for efficient cellulosic biofuel production : rational design of synthetic cellulolytic Escherichia coli. IBS 2012 15th International Biotechnology Symposium and Exhibition, 2012, Exco, Daegu, Republic of Korea.(September 16-18-21) www.ibs2012
대장균을 이용한 셀룰로스로부터 화학물질 생산 연구, 08/30/2012. KIST 중점연구회 미생물대사공학연구회 심포지움, 서울
목질계 바이오매스 유래 복합당 동시 이용 대장균 개발, 05/09/2012. 고려대학교 환경생태공학부 세미나, 서울
대장균의 불활성 셀로바이오스 오페론 활성화 및 진화적 적응을 통한 복합당 동시 이용 대장균 개발, 04/26/2012. 한국화학공학회, 제주
Light-Switchable Gene Expression System for Escherichia coli, 04/12/2012. 2012 한국생물공학회, 창원
SSF 맞춤형 인공미생물 이용 바이오매스의 바이오연료전환 기술연구, 12/21/2011. 바이오 연구회, 한양대학교, 화공생명공학부, Seoul, Korea
Engineering cellobiose metabolism in E. coli: a step towards consolidated bioprocessing, 05/12/2011. 2011 International Meeting of the Microbiological Society of Korea, Gwangju, Korea
SSF 맞춤형 인공미생물 이용 바이오매스의 바이오연료전환 기술연구, 02/11/2011. 2011 범부처 녹색기술포럼, Jeju, Korea
합성생물학을 이용한 셀룰로오스 기반 바이오화학산업, 02/09/2011. 서울대학교, 식물유전체육종연구소
Engineering Microorganisms for Biofuel Production: From Microbes to Synthetic Biology to Fuels, 07/25/2010. BIT’s World Congress of Industrial Biotechnology. China Medical Biotech Association, Dalian, China
Synthetic Biology for Biofuels: Genome Design and Engineering, 06/25/2010. International Symposium. The Korean Society for Microbiology and Biotechnology, Seoul, Korea
합성생물학과 바이오화학산업, 4/7/2010, School of Chemical and Biomolecular Engineering, Pusan Natl. Univ., Pusan, Korea
Synthetic Biology for Biofuel Production, 3/19/2010, The 4th WCU Symposium, Seoul Natl. Univ., Seoul, Korea
합성생물학 기술을 이용한 바이오화학산업, 1/20/2010, 2010년도 한국미생물-생명공학회 영남지부 학술대회, Gyeongju, Korea
From Bugs to Synthetic Biology to Biofuels, 10/22/2009. International Symposium. The Federation of Korean Microbiological Societies, Seoul, Korea
From Bugs to Synthetic Biology to Medicines, 09/25/2009. The Korean Society for Synthetic Biology, Chungbook National University, Cheongju, Korea
From Bugs to Synthetic Biology to Biofuels, 09/14/2009. School of Chemical Engineering & Bioengineering , Ulsan University, Ulsan, Korea
From Bugs to Synthetic Biology to Biofuels, 06/25/2009. International Symposium. The Korean Society for Microbiology and Biotechnology, Daejeon, Korea
From Bugs to Synthetic Biology to Biofuels, 06/01/2009. Department of Chemical Engineering, POSTECH, Korea
From Bugs to Synthetic Biology to Biofuels, 05/22/2009. Department of Environmental Engineering, Kyung Pook National University, Korea
From Bugs to Synthetic Biology to Biofuels, 05/14/2009, Department of Chemical Engineering, Chonbok National University, Korea
From Bugs to Synthetic Biology to Biofuels, 04/27/2009. Department of Biology, Jung-Ang University, Korea
The Intersection of Biofuels and Synthetic Biology, 05/23/2008. Samsung Advanced Institute of Technology (SAIT)
The Intersection of Biofuels and Synthetic Biology, 04/19/2008. KOLIS (Korean Life Scientists in the Bay Area), Spring Meeting, Stanford University
Introduction to Synthetic Biology, 06/13/2006. Environmental and Chemical Engineering Division, Chonbuk National University.
Introduction to Synthetic Biology, 06/12/2006. Korean Research Institute of Bioscience and Biotechnology (KRIBB).
Introduction to Synthetic Biology, 06/08/2006. Marine Biotechnology and Environmental Research Institute, POSTECH.
Introduction to Synthetic Biology, 06/07/2006. Environmental Biotechnology National Core Research Center, Gyeongsang National University.