Downloads

REVEL scores are freely available for non-commercial use. For other uses, please contact Weiva Sieh.

All results in a single file (526 MB)

Genome segments of up to 500,000 variants per file (viewable in Excel)

Revel scores can alternatively be downloaded from Zenodo.


May 3, 2021: Ensemble transcript IDs are included to indicate which transcript(s) the amino acid substitution applies to.

April 30, 2021: GRCh38 positions are now set to missing if liftOver produces ambiguous results, or if the referent allele has changed between builds hg19/GRCh37 and GRCh38.

February 5, 2020: All files now include GRCh38 positions (converted from hg19/GRCh37 using liftOver) in addition to hg19/GRCh37 positions.

All files are in comma-separated value (CSV) format and contain 7 fields:

  1. chr: Chromosome

  2. hg19_pos: Sequence position on the hg19 (GRCh37) human genome build (1-based coordinates)

  3. grch38_pos: Sequence position on the GRCh38 human genome build (1-based coordinates). Value is "." when there is no corresponding GRCh38 position for the variant.

  4. ref: Reference nucleotide

  5. alt: Alternate nucleotide

  6. aaref: Reference amino acid

  7. aaalt: Alternate amino acid

  8. REVEL: REVEL score

  9. Ensembl_transcriptid: Ensemble transcript ID(s) corresponding to the given amino acid substitution (multiple transcript IDs are delimited by ";")