Peer-review journal article  (*: corresponding author) 

• 1. Chen RY, Chang HS, Huang HC, Hsueh YH, Tu YK, Lee KZ*. Comorbidity of cardiorespiratory and locomotor dysfunction following cervical spinal cord injury in the rat. J Appl Physiol. 135(6): 1268-1283, 2023. 

  2. Ko CC, Lee PH, Lee JS, Lee KZ*. Spinal decompression surgery may alleviate vasopressor-induced spinal hemorrhage and extravasation during acute cervical spinal cord injury in rats. Spine J. 2023 Oct 2:S1529-9430(23)03430-7. doi: 10.1016/j.spinee.2023.09.021. 

  3. Lee KZ* and Vinit S. Modulatory effect of trans-spinal magnetic intermittent theta burst stimulation on diaphragmatic activity following cervical spinal cord contusion in the rat. Spine J. 24(2): 352-372, 2004.

  4. Liao WL and Lee KZ. CDKL5-mediated developmental tuning of neuronal excitability and concomitant regulation of transcriptome. Hum. Mol. Genet. 023 Sep 9:ddad149. doi: 10.1093/hmg/ddad149.

  5. Ren MY, Liou LM, Vinit S, Lee KZ*. Position effect of trans-spinal magnetic stimulation on diaphragmatic motor evoked potential in healthy humans. J. Appl. Physiol. 133(5):1042-1054, 2022.

  6. Michel-Flutot P, Jesus I, Mansart A, Bonay M, Lee KZ, Auré K, Vinit S. Evaluation of Gastrocnemius Motor Evoked Potentials Induced by Trans-Spinal Magnetic Stimulation Following Tibial Nerve Crush in Rats. Biology (Basel). 16;11(12):1834, 2022.

  7. Lee KZ*. Neuropathology of distinct diaphragm areas following mid-cervical spinal cord contusion in the rat. Spine J. 6:S1529-9430(22)00244-3, 2022.

  8. Lee KZ*, Liou LM, Vinit S, Ren MY. Rostral-Caudal Effect of Cervical Magnetic Stimulation on the Diaphragm Motor Evoked Potential after Cervical Spinal Cord Contusion in the Rat. J Neurotrauma. 39(9-10):683-700, 2022.

  9. Michel-Flutot P, Jesus I, Vanhee V, Bourcier CH, Emam L, Ouguerroudj A, Lee KZ, Zholudeva LV, Lane MA, Mansart A, Bonay M, Vinit S. Effects of Chronic High-Frequency rTMS Protocol on Respiratory Neuroplasticity Following C2 Spinal Cord Hemisection in Rats. Biology (Basel). 19;11(3):473, 2022.

  10. Gonzalez-Rothi EJ and Lee KZ*. Intermittent hypoxia and respiratory recovery in pre-clinical rodent models of incomplete cervical spinal cord injury. Exp. Neurol. 2021. 342: 113751.

  11. Lee KZ*, Liou LM, Vinit S. Diaphragm motor evoked potential induced by cervical magnetic stimulation following cervical spinal cord contusion in the rat. J Neurotrauma. 2021. 38(15): 2122-2140.

  12. Chiu TT, Lee KZ*. Impact of cervical spinal cord injury on the relationship between the metabolism and ventilation in rats. J. Appl. Physiol. 131(6):1799-1814, 2021.

  13. Lin MT, Vinit S, Lee KZ*. Functional role of carbon dioxide on intermittent hypoxia induced respiratory response following mid-cervical contusion in the rat. Exp. Neurol. 339: 113610, 2021.

  14. Michel-Flutot P, Mansart A, Deramaudt TB, Jesus ID, Lee KZ, Bonay M, Vinit S.. Permanent diaphragmatic deficits and spontaneous respiratory plasticity in a mouse model of incomplete cervical spinal cord injury. Respir. Physiol. Neurobiol. 284: 103568, 2021.

  15. Michel-Flutot P, Zholudeva LV, Randelman ML, Deramaudt TB, Mansart A, Bonay M., Alvarez JC, Lee KZ, Petitjean M, Lane MA, Vinit S. High frequency repetitive Transcranial Magnetic Stimulation promotes long lasting phrenic motoneuron excitability via GABAergic networks. Respir. Physiol. Neurobiol. 2021.

  16. Chang HS and Lee KZ*. Modulation of the extrinsic tongue muscle activity in response to bronchopulmonary C-fiber activation following mid-cervical contusion in the rat. J. Appl. Physiol. 128(5): 1130-1145, 2020.

  17. Wu MJ, Vinit S, Chen CL, Lee KZ*. 5-HT7 receptor inhibition transiently improves respiratory function following daily acute intermittent hypercapnic-hypoxia in rats with chronic mid-cervical spinal cord contusion. Neurorehabil. Neural. Repair. 34(4): 333-343, 2020.

  18. Wen MH, Wu MJ, Vinit S, Lee KZ*. Modulation of serotonin and adenosine 2A receptors on intermittent hypoxia-induced respiratory recovery following mid-cervical contusion in the rat. J Neurotrauma. 36(21):2991-3004, 2019.

  19. Lee KZ* and Hwang JC. Modulation of glycinergic inhibition on respiratory rhythmic hypoglossal bursting in the rat. Chin. J. Physiol. 62: 27-34, 2019.

  20. Lee KZ*. Impact of cervical spinal cord contusion on the breathing pattern across the sleep-wake cycle in the rat. J. Appl. Physiol. 126(1): 111-123, 2019.

  21. Zaki Ghali MG, Britz G, Lee KZ. Pre-phrenic interneurons: characterization and role in phrenic pattern formation and respiratory recovery following spinal cord injury. Respir Physiol Neurobiol. 265:24-31, 2019.

  22. Lee KZ* and Xu KJ. The impact of cervical spinal cord contusion on the laryngeal resistance in the rat. J Neurotrauma. 36(3): 448-459, 2019.

  23. Lee KZ*. Upper airway motor outputs in response to activation of bronchopulmonary C-fibers. Adaptive Medicine 10(3): 103-108, 2018.

  24. Lee KZ* and Liao W. Loss of CDKL5 disrupts respiratory function in mice. Respir. Physiol. Neurobiol. 248: 48-54, 2018.

  25. Wen MH and Lee KZ*. Diaphragm and intercostal muscle activity following mid-cervical spinal cord contusion in the rat. J Neurotrauma.  35(3): 533-547, 2018.

  26. Lee KZ* and Gonzalez-Rothi EJ. Contribution of 5-HT2A receptors on diaphragmatic recovery after chronic cervical spinal cord injury.  Respir. Physiol. Neurobiol. 244: 51-55, 2017.

  27. Lee KZ*, Hsu SH. Compensatory function of the diaphragm following high cervical hemisection in the rat. J Neurotrauma. 34: 2634–2644, 2017.

  28. Lin CC, Lai SR, Shao YH, Chen CL, Lee KZ*. The therapeutic effectiveness of delayed fetal spinal cord tissue transplantation on respiratory function following mid-cervical spinal cord injury. Neurotherapeutics. 14: 792 – 809, 2017.

  29. Lee KZ*, Chiang SC, Li YJ. Mild acute intermittent hypoxia improves respiratory function in unanesthetized rats with midcervical contusion. Neurorehabil. Neural. Repair. 31(4):364-375, 2017.

  30. Sandhu MS, Ross HH, Lee KZ, Ormerod BK, Reier PJ, Fuller DD. Intraspinal transplantation of subventribular zone-derived neural progenitor cells improves phrenic motor output after high cervical spinal cord injury. Exp. Neurol. 287(2): 205-215, 2017.

  31. Lee KZ* and Kuo HC. Vagal control of breathing pattern following mid-cervical contusion in rat. J. Neurotrauma. 34(3):734-745, 2017.

  32. Lee KZ*. Phrenic motor outputs in response to bronchopulmonary C-fibre activation following chronic cervical spinal cord injury. J. Physiol. 594(20): 6009-6024, 2016.

  33. ElMallah MK, Stanley DA, Lee KZ, Turner SMF, Streeter KA, Baekey DM, Fuller DD. Power spectral analysis of hypoglossal nerve activity during intermittent  hypoxia-induced long term facilitation in mice. J. Neurophysiol. 115(3): 1372-1380, 2016

  34. Dougherty BJ, Gonzalez-Rothi EJ, Lee KZ, Ross HH, Reier PJ, Fuller DD. Respiratory outcomes after mid-cervical transplantation of embryonic medullary cells in rats with cervical spinal cord injury. Exp. Neurol. 278: 22-26, 2016.

  35. Hsu SH, Lee KZ*. Effects of serotonergic agents on respiratory recovery after cervical spinal injury. J. Appl. Physiol. 119(10): 1075-1087, 2015.

  36. Gonzalez-Rothi EJ, Lee KZ, Dale EA, Reier PJ, Mitchell GS, Fuller DD. Intermittent hypoxia and neurorehabilitation. J. Appl. Physiol. 119(12): 1455-1465, 2015.

  37. Lee KZ, Sandhu MS, Dougherty BJ, Reier PJ, Fuller DD. Hypoxia triggers short term potentiation of phrenic motoneuron discharge after chronic cervical spinal cord injury. Exp. Neurol. 263: 314-324, 2015.

  38. Lee KZ*, Chang YS. Recovery of the pulmonary chemoreflex and functional role of bronchopulmonary C-fibers following chronic cervical spinal cord injury. J. Appl. Physiol. 117(10):1188-1198, 2014.

  39. Tsai IL, Lee KZ*. Attenuation of the pulmonary chemoreflex following acute cervical spinal cord injury. J. Appl. Physiol. 116(7): 757-766, 2014.

  40. Lee KZ*, Huang YJ, Tsai IL. Respiratory motor outputs following unilateral mid-cervical spinal cord injury in the adult rat. J. Appl. Physiol. 116 (4): 395-405, 2014.

  41. Gill LC, Ross HH, Lee KZ, Gonzalez-Rothi EJ, Dougherty BJ, Judge AR, Fuller DD. Rapid diaphragm atrophy following cervical spinal cord hemisection. Respir. Physiol. Neurobiol. 192: 66-73, 2014

  42. Lee KZ, Lane MA, Dougherty BJ, Mercier LM, Sandhu MS, Sanchez JC, Reier PJ, Fuller DD. Intraspinal transplantation and modulation of donor neuron electrophysiolgical activity Exp. Neurol. 251: 47-57, 2014.

  43. Lee KZ, Dougherty BJ, Sandhu MS, Lane MA, Reier PJ, Fuller DD. Phrenic motoneuron discharge patterns following chronic cervical spinal cord injury. Exp. Neurol. 249: 20-32, 2013.

  44. Sandhu MS, Lee KZ, Gonzalez-Rothi EJ, Fuller DD. Repeated intravenous doxapram induces phrenic motor facilitation. Exp. Neurol. 250C: 108-115, 2013.

  45. Fuller DD, Lee KZ, Tester NJ. The impact of spinal cord injury on breathing during sleep. Respir. Physiol. Neurobiol. 188(3): 344-354, 2013.

  46. Falk DJ, Mah CS, Soustek MS, Lee KZ, Elmallah MK, Cloutier DA, Fuller DD, Byrne BJ. Intrapleural administration of AAV9 improves neural and cardiorespiratory function in Pompe disease. Mol. Ther. 21(9): 1661-1667, 2013. 

  47. Lee KZ*, Fuller DD, Hwang JC. Pulmonary C-fiber activation attenuates respiratory-related tongue movements. J. Appl. Physiol. 113(9): 1369–1376, 2012.  

  48. Dougherty BJ, Lee KZ, Gonzalez-Rothi EJ, Lane MA, Reier PJ, Fuller DD. Recovery of inspiratory intercostals muscle activity following high cervical hemisection. Respir. Physiol. Neurobiol. 183(3):186-192, 2012.  

  49. ElMallah MK, Falk DJ, Lane MA, Conlon TJ, Lee KZ, Shafi NI, Reier PJ, Byrne BJ, Fuller DD. Retrograde gene delivery to hypoglossal motoneurons using AAV9. Hum. Gene Ther. Methods. 23(2):148-156, 2012.

  50. Dougherty BJ, Lee KZ, Lane MA, Reier PJ, Fuller DD. The contribution of the spontaneous crossed-phrenic phenomenon to inspiratory tidal volume in spontaneously breathing rats. J. Appl. Physiol. 112 (1): 96-105, 2012.

  51. Lane MA, Lee KZ, Salazar K, O’Steen BE, Bloom DC, Fuller DD, Reier PJ. Respiratory function following bilateral mid-cervical contusion injury in the adult rat. Exp. Neurol. 235 (1): 197-210, 2012.

  52. Lee KZ, Fuller DD. Invited review: Neural control of phrenic motoneuron discharge. Respir. Physiol. Neurobiol. 179 (1): 71-79, 2011.

  53. Lee KZ, Qiu K, Sandhu MS, Elmallah MK, Falk DJ, Lane MA, Reier PJ, Byrne BJ, Fuller DD. Hypoglossal neuropathology and respiratory activity in Pompe mice. Front. Physiol. 2: 31(P1-P10), 2011.

  54. Lee KZ*, Sandhu MS, Dougherty BJ, Reier PJ, Fuller DD. Influence of vagal afferents on supraspinal and spinal respiratory activity following cervical spinal cord injury in rats. J. Appl. Physiol. 109(2): 377-387, 2010.

  55. Lee KZ*, Fuller DD. Hypoxia induced short-term potentiation of respiratory-modulated facial motor output in the rat. Respir. Physiol. Neurobiol. 173(1): 107-111, 2010.

  56. Lee KZ*, Fuller DD. Pre-inspiratory and inspiratory hypoglossal motor output during hypoxia induced plasticity in the rat. J. Appl. Physiol. 108(5): 1187-1198, 2010.

  57. Qiu K, Lane MA, Lee KZ, Reier PJ, Fuller DD. The phrenic motor nucleus in the adult mouse. Exp. Neurol. 226(1): 254-258, 2010.

  58. Sandhu MS, Lee KZ, Fregosi RF, Fuller DD. Phrenicotomy alters phrenic long term facilitation (LTF) following intermittent hypoxia in anesthetized rats. J. Appl. Physiol. 109(2): 279-287, 2010.

  59. Lee KZ*, Reier PJ, Fuller DD. Phrenic motoneuron discharge patterns during hypoxia-induced short term potentiation. J. Neurophysiol. 102(4): 2184-2193, 2009.

  60. Lane MA, Lee KZ, Fuller DD, Reier PJ. Spinal circuitry and respiratory recovery following spinal cord injury. Respir. Physiol. Neurobiol. 169(2): 123-132, 2009.

  61. Lee KZ, Fuller DD, Lu IJ, Ku LC, Hwang JC. Pulmonary C-fiber receptor activation abolishes uncoupled facial nerve activity from phrenic bursting during positive end-expired pressure in the rat. J. Appl. Physiol. 104(1): 119-129, 2008.

  62. Lee KZ, Fuller DD, Tung LC, Lu IJ, Ku LC, Hwang JC. Uncoupling of upper airway motor activity from phrenic bursting by positive end-expired pressure in the rat. J. Appl. Physiol. 102(3): 878-889, 2007.

  63. Lee KZ, Fuller DD, Lu IJ, Lin JT, Hwang JC. Neural drive to tongue protrudor and retractor muscles following pulmonary C-fiber activation. J. Appl. Physiol. 102(1): 434-444, 2007.

  64. Lu IJ, Lee KZ, Hwang JC. Capsaicin-induced activation of pulmonary vagal C-fibers produces reflex laryngeal closure in the rat. J. Appl. Physiol. 101(4): 1104-1112, 2006.

  65. Yang SJ, Lee KZ, Wu CH, Lu KT, Hwang JC. Vasopressin produces inhibition on phrenic nerve activity and apnea through V(1A) receptors in the area postrema in rats. Chin. J. Physiol. 49(6): 313-325, 2006.

  66. Tsai CY, Wu CC, Lee KZ, Hwang JC. Muscarinic M2 receptor mediates bradycardai and hypotention induced by capsaicin administration in the rat. BioFormosa 40(1): 25-35, 2005.

  67. Lu IJ, KZ Lee, Lin JT, Hwang JC. Capsaicin administration inhibits the abducent branch but excites the thyroarytenoid branch of the recurrent laryngeal nerves in the rat. J. Appl. Physiol. 98: 1646-1652, 2005.

  68. Lee KZ, Lu IJ, Ku LC, Lin JT, Hwang JC. Response of respiratory-related hypoglossal nerve activity to capsaicin-induced pulmonary C-fiber activation in rats. J. Biomed. Sci. 10 (6 Pt 2): 706-717, 2003.

  69. Lu IJ, Ku LC, Lin JT, Lee KZ, Hwang JC. Pulmonary C-fiber activation enhances respiratory-related activities of the recurrent laryngeal nerve in rats. Chin. J. Physiol. 45(4): 143-154, 2002.