Presentations, posters, etc

Published Abstracts

1. Hancock, B.C., York, P. & Rowe, R.C., Wet granulation interactions in a model powder system, Journal of Pharmacy and Pharmacology 42 (1990) 79P (Principal investigator).

2. Hancock, B.C., York, P. & Rowe, R.C., Wet granulation studies using a mixer torque rheometer, Pharmaceutical Research 7 (1990) S70 (Principal investigator).

3. Hancock, B.C. & Zografi, G., The use of solution theories for modeling water vapour absorption by pharmaceutical solids, Pharmaceutical Research 10 (1993) S176 (Principal investigator).

4. Hancock, B.C. & Zografi, G. The relationship between the glass transition temperature and water content of amorphous pharmaceutical solids, Pharmaceutical Research, 10 (1993) S279 (Principal investigator).

5. Yoshioka, M., Hancock, B.C. & Zografi, G., Crystallisation of indomethacin from the amorphous state below and above its glass transition temperature, Pharmaceutical Research 11 (1994) S215 (Co‑investigator).

6. Hancock, B.C., Shamblin, S.L. & Zografi, G., Molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures, Pharmaceutical Research 11 (1994) S215 (Principal investigator).

7. Thibert, R. & Hancock, B.C., Direct visualisation of superdisintegrant hydration using environmental scanning electron microscopy, Pharmaceutical Research 13 (1996) S347 (Co‑investigator).

8. Dalton, C.R. & Hancock, B.C., Water vapour sorption by some pharmaceutical excipients and their formulations, Pharmaceutical Research 13 (1996) S354 (Principal investigator).

9. Hancock, B.C., Bruneau, N. & Clas, S.‑D. Thermal expansion behaviour of coated and uncoated tablets using thermomechanical analysis, Pharmaceutical Research 13 (1996) S355 (Principal investigator).

10. Hancock, B.C., Dalton, C.R., Pikal, M.J. & Shamblin, S.L. Is there a simple calorimetric method for determining the fragility of amorphous pharmaceutical materials? Pharmaceutical Research 14 (1997) S189 (Principal investigator).

11. Thibert, R., Dalton, C.R., Moallemi, A.R., Projean, D. & Hancock, B.C. The effect of surfactant addition on the surface and bulk properties of some pharmaceutical polymer solutions, Pharmaceutical Research 14 (1997) S482 (Co‑investigator).

12. Dalton, C.R. & Hancock, B.C. The effect of temperature on water vapour sorption by amorphous pharmaceutical sugars, Pharmaceutical Research 14 (1997) S193 (Principal investigator).

13. Dalton, C.R., Hancock, B.C. & Clas, S.‑D. Microscale investigation of the dynamic mechanical properties of microcrystalline cellulose compacts using thermomechanical analysis, Pharmaceutical Research 14 (1997) S196 (Principal investigator).

14. Shamblin, S.L., Tang, X., Chang, L., Hancock, B.C. & Pikal, M.J. Comparison of the heat capacity of materials in the crystalline and amorphous states, PharmSci 1 (1998) S405 (Co‑investigator).

15. Shamblin, S.L., Hancock, B.C. & Pikal, M.J. An investigation of the meaning of the relaxation time constants in the Kohlraush‑Williams‑Watts expression, PharmSci 1 (1998) S403 (Co‑investigator).

16. Dalton, C.R., Hancock, B.C. and Clas, S.‑D. Micro‑scale investigation of the dynamic mechanical properties of microcrystalline cellulose compacts using a dynamic mechanical analyser, PharmSci 1 (1998) S311 (Principal investigator).

17. Hancock, B.C., Dupuis, Y. and Thibert, R. Determination of the viscosity of an amorphous drug using thermomechanical analysis (TMA), PharmSci 1 (1998) S402 (Principal investigator).

18. Shamblin, S.L., Hancock, B.C. and Pikal, M.J. The chemical stability of amorphous cefoxitin sodium in the presence of glassy stabilizers, PharmSci 2 (1999) 803 (Co‑investigator).

19. Thibert, R. and Hancock, B.C. Effect of milling upon superdisintegrant properties and actions, PharmSci 2 (1999) 1280 (Co‑investigator).

20. Hancock, B.C. and Parks, M. Evaluating the solubility advantage for amorphous pharmaceuticals, PharmSci 2 (1999) 796 (Principal investigator).

21. Wu, C.Y., Elliot, J.A., Bentham, A.C., Best, S.M., Hancock, B.C. & Bonfield,W. A numerical study on the mechanical behaviour of pharmaceutical powders. Proceedings of the International Conference on Pharmaceutics, Biopharmaceutics & Pharmaceutical Technology, Nuremburg, Germany (March 2004) 17-18 (Co‑investigator).

22. Dutt, M., Elliott, J.A., Bentham, A.C. & Hancock, B.C. Characterization studies of spherical particle packings resulting from gravity compaction. Bulletin of the American Physical Society 49 (2004) 1 (Co‑investigator).

23. Fu, X.W., Milroy, G.E., Dutt, M., Bentham, A.C., Hancock, B.C. & Elliott, J.A. Quantitative analysis of packed and compacted granular system by X-ray microtomography, Proceedings of the Society of Photo-Optical Instrumentation Engineers (SPIE) 5747 Pt. 1-3, (2005)1955 (Co‑investigator).

24. Bentham, A.C., Dutt, M., Hancock, B.C. & Elliott, J.A. Effects of size polydispersity on pharmaceutical particle packings, Powders and Grains 2005, ed. Garcia-Rojo, R., Herrmann, H.J. & McNamara, S., Balkema, Rotterdam (2005) (Co‑investigator).

25. Dutt, M., Hancock, B.C., Bentham, A.C. & Elliott, J.A. Studies of particle packings in mixtures of pharmaceutical excipients, Powders and Grains 2005, ed. Garcia-Rojo, R., Herrmann, H.J. & McNamara, S., Balkema, Rotterdam, (2005) (Co‑investigator).

26. Hancock, B.C., Dutt, M., Bentham, A.C. & Elliott, J.A. Ordered packing induced by simultaneous shear and compaction, Powders and Grains 2005, ed. Garcia-Rojo, R., Herrmann, H.J. & McNamara, S., Balkema, Rotterdam, (2005) (Co‑investigator).

Invited lectures

1. Wet granulation interactions in a model powder system, British Pharmaceutical Conference, Cardiff, UK (September 1990).

2. Prediction of wet granulation behaviour from surface free energy considerations, Institution of Chemical Engineers Particle Technology Research Award, London, UK (October 1990).

3. Particle interactions and thermodynamic phenomena in size enlargement processes, I.C.I. Pharmaceuticals PLC, Macclesfield, UK (December 1990).

4. Mixing kinetics of an Avicel PH101‑water system, New Pharm '91, Loughborough, UK (April 1991).

5. Material interactions and surface phenomena in size enlargement processes, Department of Chemical Engineering, University of Surrey, Guilford, UK (October 1991).

6. The use of solution theories for modeling water vapour absorption by pharmaceutical solids, Second Annual Symposium on The Effects of Water on the Molecular Mobility of Crystalline and Amorphous Pharmaceutical Solids, Madison, WI, USA (September 1992).

7. Material interactions and surface phenomena in size enlargement processes, College of Pharmacy, University of Minnesota, MN, USA (October 1992).

8. Material interactions and surface phenomena in size enlargement processes, Smith Kline Beecham Pharmaceuticals, Philadelphia, PA, USA (November 1992).

9. The relationship between the glass transition temperature and water content of amorphous pharmaceutical solids, Third Annual Symposium on The Effects of Water on the Molecular Mobility of Crystalline and Amorphous Pharmaceutical Solids, Madison, WI, USA (September 1993).

10. The use of solution theories for modeling water vapour absorption by pharmaceutical solids, American Association of Pharmaceutical Scientists Conference, Orlando, FL, USA (November 1993).

11. The molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures, Fourth Annual Symposium on The Effects of Water on the Molecular Mobility of Crystalline and Amorphous Pharmaceutical Solids, Madison, WI, USA (September 1994).

12. Careers in pharmaceutical research, 16th Annual Undergraduate Research Seminar, West Virginia University School of Pharmacy, Morgantown, WV, USA (November 1994).

13. Solid‑state drug‑excipient interactions and their effect on the stability of pharmaceutical products, American Association of Pharmaceutical Scientists Eastern Regional Meeting, New Brunswick, NJ, USA (June 1995).

14. Effect of solid‑state processing on water vapour sorption by aspirin, Fifth Annual Symposium on the Effects of Water on the Molecular Mobility of Crystalline & Amorphous Solids, West Lafayette, IN, USA (September 1995).

15. Viscoelastic properties of pharmaceutical granulations, American Association of Pharmaceutical Scientists Annual meeting, Miami, FL, USA (November 1995).

16. Water vapour sorption in pharmaceutical systems. Two day residential course, Miami, FL, USA (April 1996).

17. Impact of amorphous carbohydrate properties on pharmaceutical formulation technologies, Girton Conference on Amorphous Carbohydrates, Cambridge, UK (September 1996).

18. Characteristics and significance of the amorphous state in pharmaceutical systems. Graduate lecture at the University of Michigan School of Pharmacy, MI, USA (March 1997).

19. Control of particulate properties in multi‑component systems: wet granulation, International Industrial Pharmaceutical Research and Development Conference, University of Wisconsin, WI, USA (June 1998).

20. Understanding amorphous pharmaceuticals: challenges and opportunities. Three day residential course, Bioupdate Foundation, Amersfoort, Holland (March 1999).

21. Qualitative and quantitative analysis of amorphous pharmaceuticals, American Association of Pharmaceutical Scientists Eastern Regional Meeting, Parsipanny, NJ, USA (June 1999)

22. Mechanical property testing of pharmaceutical powders and compacts, American Association of Pharmaceutical Scientists “Arden House” Conference, Harriman, New York, USA (January 2001).

23. Molecular disorder in pharmaceutical systems – how do I know when I’ve got it?, Graduate lecture at the University of Iowa College of Pharmacy, Iowa City, IO, USA (April 2000).

24. Making sense of disordered pharmaceutical materials, Graduate lecture at the University of Iowa College of Pharmacy, Iowa City, IO, USA (April 2000).

25. Mechanical properties of pharmaceutical powders and compacts, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2001).

26. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2001).

27. Disordered drug delivery: defining the dream, and setting direction, Center for Pharmaceutical Processing Research Freeze-Drying of Pharmaceuticals and Biologicals Conference, Breckenridge, CO, USA (August 2001).

28. Disordered drug delivery: destiny, dynamics and the Deborah number, Royal Pharmaceutical Society of Great Britain Science Medal Lecture, British Pharmaceutical Conference, Glasgow, UK (September 2001).

29. Mechanical property testing of pharmaceutical powders and compacts, Department Seminar, School of Pharmacy, Purdue University, West Lafayette, IN, USA (January 2002).

30. Predicting scale-up issues: the Pfizer approach, American Association of Pharmaceutical Scientists Pharmaceutics & Drug Delivery Conference, Washington DC, USA (April 2002).

31. Predicting how to turn powders into tablets, Department Seminar, School of Pharmacy, University of Kentucky, Lexington, KY, USA (December 2002).

32. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2003).

33. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2004).

34. Identifying candidates for direct compression using material-sparing formulation tools, American Association of Pharmaceutical Scientists Annual Conference, Baltimore, MD, USA (October 2004).

35. Mechanical properties of powders, Graduate lecture at Purdue University School of Pharmacy, West Lafayette, IN, USA (October 2004).

36. Identifying candidates for direct compression using material-sparing formulation tools, 2^nd Annual Peck Symposium in Industrial Pharmacy, Purdue University, IN, USA (October 2004).

37. Impact of particle properties on powder flow, compaction and compact mechanical properties, American Association of Pharmaceutical Scientists “Arden House” Conference, Harriman, New York, USA (January 2005).

38. Water-solid interactions, American Association of Pharmaceutical Scientists “Arden House” Conference, Harriman, New York, USA (January 2005).

39. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2005).

40. Miniaturized powder and compact characterization techniques: how small can we go? American Association of Pharmaceutical Scientists Annual Meeting, Nashville, TN, USA (November 2005).

41. Fluidization segregation in formulation development and equipment design, New Jersey Pharmaceutical Association for Science & Technology, Somerset, NJ, USA (March 2006).

42. Current Status: Measurement & Prediction of Solid Properties. National Institute for Pharmaceutical Education & Technology, Gaithersburg, MD, USA (April 2006).

43. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2006).

44. Development of a material-sparing fluidization segregation tester for use with pharmaceutical blends and granulations, Graduate lecture at University of Florida School of Chemical Engineering, Gainesville, FL, USA (January 2007).

45. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2007).

46. Small scale predictive approaches for rapid and robust formulation design, M3: Molecules, Materials Medicines Conference, Reykjavik, Iceland (May 2007).

47. Materials characterization and solid dosage form development, Purdue University Short Course, West Lafayette, IN, USA (July 2007).

48. Interpretation of powder property data to design quality into formulations and processes. American Association of Pharmaceutical Scientists Annual Meeting, San Diego, CA, USA (November 2007)

49. The problems with using granular materials as drug-delivery systems, and how we can do better in future, New York Academy of Sciences, New York, NY, USA (January 2008).

50. Particle and powder property measurements for predicting processing performance, Particulate Processes in the Pharmaceutical Industry II Conference, San Juan, PR, USA (February 2008).

51. From particles to powders to products: predicting properties and performance, American Association of Pharmaceutical Scientists “Arden House” Conference, West Point, New York, USA (January 2008).

52. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2008).

53. The problems with using granular materials as drug-delivery systems, and how we can do better in the future, Engineering Mechanics Conference, Minneapolis, MN, USA (May 2008)

54. Materials characterization and solid dosage form development, Purdue University Short Course, West Lafayette, IN, USA (July 2008).

55. Mechanical property testing during the development of pharmaceutical dosage forms, Lems Seminar at Clarkson University, Potsdam, NY, USA (October 2008).

56. Identifying candidates and selecting excipients for direct compression using Quality by Design principles, 5^th Association for Innovative Formulation Technology Conference, Osaka, Japan (November 2008).

57. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2009).

58. Using emerging predictive tools to accelerate drug product development, Molecules-Materials-Medicines conference, Santa Barbara, CA, USA (May 2009)

59. QbD for solid dosage forms: designing tablet formulations based on API physical properties, University of Wisconsin Short Course, Somerset, NJ, USA (October 2009).

60. Application of materials science principles to solid dosage form design & process development, American Association of Pharmaceutical Scientists ‘webinar’ (October 2009).

61. Excipient variability: Why one lot is different than another. American Association of Pharmaceutical Scientists Annual Meeting, Los Angeles, CA, USA (November 2009).

62. Pharmaceutical powder flow: properties, problems, and predictions, School of Pharmacy Seminar at University of Connecticut, Storrs, CT, USA (January 2010).

63. Principles of solid dosage forms, University of Wisconsin Principles of Solid Dosage Forms Course, Madison, WI, USA (May 2010).

64. Using predictive tools for rapid formulation development: The Pfizer experience, Land O’Lakes Drug Product Development conference, Merrimac, WI, USA (June 2010).

65. Using predictive tools for rapid formulation development, Academy of Pharmaceutical Sciences conference, Nottingham, UK (September 2010).

66. Using emerging predictive tools to accelerate drug product development, New Jersey Institute of Technology, Newark, NJ, USA (November 2010).

67. How engineering is helping to develop a cure for cancer, School of Chemical Engineering Seminar University of Rhode Island, Kingston, RI, USA (April 2011).

68. Excipient performance evaluation for intelligent formulation design, International Forum on Process Analytical Chemistry (IFPAC) meeting, Baltimore, MD, USA (January 2012).

69. Revolutionizing drug product development using computational product and process design, American Association of Pharmaceutical Scientists North Eastern Regional Discussion group, Rocky Hill, CT, USA (April 2012).

70. Pharmaceutical materials testing to enable computational product & process design, School of Pharmacy, Uppsala University, Sweden (March 2012).

71. Revolutionizing drug product development using computational product and process design, American Association of Pharmaceutical Scientists Annual Meeting, Chicago, IL, USA (October 2012).

72. Simulation of roll compaction, Compaction Simulator Users Group Meeting, Boston, MA, USA (November 2012).

73. Basic principles of materials science with application to pharmaceutical materials, American Association of Pharmaceutical Scientists Arden conference, Washington DC, USA (March 2013).

Other presentations (posters, etc)

1. Wet granulation studies using a mixer torque rheometer. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Las Vegas, NV, USA (November 1990).

2. Wet granulation interactions in model powder systems. Poster presentation at I.C.I. Science Link '91, Macclesfield, UK. (February 1991).

3. The relationship between the glass transition temperature and water content of amorphous pharmaceutical solids. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Orlando, FL, USA (November 1993).

4. The molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Diego, CA, USA (November 1994).

5. Direct visualisation of superdisintegrant hydration using environmental scanning electron microscopy. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Seattle, WA, USA (November 1996).

6. Water vapour sorption by some pharmaceutical excipients and their formulations. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Seattle, WA, USA (November 1996).

7. Thermal expansion behaviour of coated and uncoated tablets using thermomechanical analysis. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Seattle, WA, USA (November 1996).

8. Comparison of the heat capacity of materials in the crystalline and amorphous states. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Francisco, CA, USA (November 1998).

9. An investigation of the meaning of the relaxation time constants in the Kohlraush‑Williams‑Watts expression. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Francisco, CA, USA (November 1998).

10. Micro‑scale investigation of the dynamic mechanical properties of microcrystalline cellulose compacts using a dynamic mechanical analyser. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Francisco, CA, USA (November 1998).

11. Determination of the viscosity of an amorphous drug using thermomechanical analysis (TMA). Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Francisco, CA, USA (November 1998).

12. The chemical stability of amorphous cefoxitin sodium in the presence of glassy stabilizers. Poster presentation at the American Association of Pharmaceutical Scientists Conference, New Orleans, LA, USA (November 1999).

13. Effect of milling upon superdisintegrant properties and actions. Poster presentation at the American Association of Pharmaceutical Scientists Conference, New Orleans, LA, USA (November 1999).

14. Evaluating the solubility advantage for amorphous pharmaceuticals. Poster presentation at the American Association of Pharmaceutical Scientists Conference, New Orleans, LA, USA (November 1999).

15. Development of an avalanche testing method for the routine determination of powder cohesivity. Poster presentation at the American Association of Pharmaceutical Scientists North East Regional Discussion Group meeting, Rocky Hill, CT, USA (May 2001).

16. Comparison of the mechanical properties of the crystalline and amorphous forms of a drug substance. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Denver, CO, USA (October 2001).

17. Inter-site comparison of a powder avalanche testing procedure for the determination of powder flow. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Denver, CO, USA (October 2001).

18. Evaluation of the mechanical property anisotropy of uni-axially compacted pharmaceutical powders. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Denver, CO, USA (October 2001).

19. Non-invasive X-ray powder diffraction quantitation of glycine polymorphs in intact compacts and modeling of intensity variations with sample thickness and solid fraction. Poster presentation at the PPXRD-2 Conference, Washington D.C. (December 2002)

20. Modelling packing and compaction of pharmaceutical powders: a combined numerical and experimental study. Poster presentation at the International Fine Particle Research Institute (IFPRI) meeting, Harrogate, UK (June 2003).

21. Studies on the tableting process: from grains to tablets. Poster presentation at the 5^th UK Particle Technology Forum, Sheffield, UK (July 2003).

22. Investigating spherical packing from free-flowing powders using a novel combination of modeling and X-ray microtomography. Poster presentation at the 5^th UK Particle Technology Forum, Sheffield, UK (July 2003).

23. Numerical experiments on packings of spherical particles, workshop on flow regimes, transitions and segregation in granular & particle-laden flow. Poster presentation at the Newton Institute of Mathematical Sciences meeting, Cambridge, UK (September 2003).

24. Evaluation of the surface acidity of pharmaceutical excipients and formulations using pH indicators as probe molecules and diffuse reflectance spectroscopy. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Salt lake City, UT, USA (October 2003).

25. Comparison of three pharmaceutical powder flowability tests. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Salt lake City, UT, USA (October 2003).

26. X-ray microtomography for the non-destructive structure determination of solid dosage forms. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Salt lake City, UT, USA (October 2003).

27. Characterizing the hydration and drug release of controlled release formulations using X‑ray microtomography. Poster presentation at the Materials Congress, London, UK (March 2004).

28. Studies of spherical particle packings arising from uni-axial compaction. Poster presentation at the American Physical Society meeting, Montreal, Canada (March 2004).

29. The use of desktop X-ray microtomography to characterize randomly packed and compacted pharmaceutical particulate systems. Poster presentation at the Materials Congress, London, UK (March 2004).

30. Characterising randomly packed and compacted pharmaceutical particulate systems using X-ray microtomography. Poster presentation at the 7th World Biomaterials Congress, Sydney, Australia (May 2004).

31. Finite element analysis of the failure mechanisms during tableting. Poster presentation at the 6^th UK Particle Technology Forum, University College, London, UK (June 2004).

32. Surface acidity of pharmaceutical excipients: effect of formulation variables. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Baltimore, MD, USA (October 2004).

33. Evaluating powder flow data repeatability and reproducibility with the Schulze ring shear tester. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Baltimore, MD, USA (October 2004).

34. Quantitative analysis of packed and compacted granular systems by X-ray microtomography. Presentation at the SPIE International Symposium on Medical Imaging, San Diego, CA, USA (February 2005).

35. Studies of particle packings in mixtures of pharmaceutical excipients. Poster presentation at the American Physical Society Meeting, San Francisco, CA, USA (March 2005).

36. Ordered packing induced by simultaneous shear and compaction. Poster presentation at the American Physical Society Meeting, San Francisco, CA, USA (March 2005).

37. Effects of size poly-dispersity on pharmaceutical particle packings. Poster presentation at the American Physical Society Meeting, San Francisco, CA, USA (March 2005).

38. Modeling packing and compaction of pharmaceutical powders: a combined numerical and experimental study. Poster presentation at the International Fine Particle Research Institute Meeting, Leeds, UK (June 2005).

39. Numerical and experimental investigation of capping mechanisms during tablet compaction. Poster presentation at the Particle Processes in the Pharmaceutical Industry Conference, Montreal, Canada (June 2005).

40. Finite element analysis of capping mechanisms during pharmaceutical powder compaction. Poster presentation at the PM2TEC2005 Conference, Montreal, Canada (June 2005).

41. Studies of particle packings in mixtures of pharmaceutical excipients. Poster presentation at the Powders & Grains Conference, Stuttgart, Germany (July 2005).

42. Ordered packing induced by simultaneous shear and compaction. Poster presentation at the Powders & Grains Conference, Stuttgart, Germany (July 2005).

43. Effects of size polydispersity on pharmaceutical particle packings. Poster presentation at the Powders & Grains Conference, Stuttgart, Germany (July 2005).

44. A method for measuring the tensile strength of bi‑layer compacts. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Nashville, TN, USA (November 2005).

45. Effects of particle size dispersity on the response to compressive strains. Poster presentation at the American Physical Society meeting, Baltimore, USA (March 2006).

46. Effect of relative material stiffness of binary mixture components to compression. Poster presentation at the American Physical Society meeting, Baltimore, USA (March 2006).

47. Granular templating: effects of boundary structure on particle packings under simultaneous shear and compression. Poster presentation at the American Physical Society meeting, Baltimore, USA (March 2006).

48. Granular templating: effects of boundary structure on particle packings under simultaneous shear and compression. Poster presentation at the GRC Granular & Granular Fluid meeting, Oxford, UK (July 2006).

49. Influence of particle size dispersity in dense packings on the interparticle contact state. Poster presentation at the 7^th UK Particle Technology Forum, London, UK (September 2006).

50. Microscopic and macroscopic studies of pharmaceutical excipient mixtures. Poster presentation at the 7th UK Particle Technology Forum, London, UK (September 2006).

51. Impact of API melting point on bulk mechanical properties. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Antonio, TX, USA (November 2006).

52. Development of a material-sparing fluidization segregation tester for use with pharmaceutical blends and granulations. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Antonio, TX, USA (November 2006).

53. Influence of particle size dispersity in dense packings on the void structure and the interparticle contact state. Poster presentation at the American Physical Society meeting, Denver, USA (March 2007).

54. The behavior of ultrafine particles in the absence and presence of external fields. Poster presentation at the American Physical Society meeting, Denver, USA (March 2007).

55. Numerical studies of ultrafine particles: a simple model and their behavior in the absence and presence of external fields. Poster presentation at the satellite meeting of StatPhys: Statics and dynamics of granular media and colloidal suspensions, Naples, Italy (July 2007).

56. The effect of particle size dispersity in dense packings on the void structure and the interparticle contact state. Poster presentation at the satellite meeting of StatPhys: Statics and dynamics of granular media and colloidal suspensions, Naples, Italy (July 2007).

57. The effect of surface properties on the behavior of ultrafine particles. Poster presentation at the Particle Technology Forum, Cambridge, UK (September 2007).

58. Numerical simulations on pharmaceutical powder compaction. Poster presentation at the 5^th International Conference on Physical and Numerical Simulation of Materials Processing, Zhengzhou City, China (September 2007).

59. Assessing the discharge performance of hoppers using the discrete element method. Presentation at the American Institute of Chemical Engineers Conference, Salt lake City, UT, USA (November 2007).

60. Segregation of cohesive particles during hopper discharge. Presentation at the American Institute of Chemical Engineers Conference, Salt lake City, UT, USA (November 2007).

61. The effect of lot-to-lot particle size variation in Avicel PH grades of microcrystalline cellulose on bulk powder and compact properties. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Diego, CA, USA (November 2007).

62. Understanding variability in tensile strength measurements of pharmaceutical compacts. Poster presentation at the American Association of Pharmaceutical Scientists Conference, San Diego, CA, USA (November 2007).

63. Predicting discharge dynamics from a rectangular hopper using the discrete element method (DEM). Presentation at the American Institute of Chemical Engineers Conference, Philadelphia, PA, USA (November 2008).

64. The effect of particle shape on bulk powder friction in a Schulze ring shear tester using the discrete element method (DEM). Presentation at the American Institute of Chemical Engineers Conference, Philadelphia, PA, USA (November 2008).

65. Finite element analysis of tablet compaction using a modified material plasticity model. Presentation at the American Institute of Chemical Engineers Conference, Philadelphia, PA, USA (November 2008).

66. Force model considerations for glued sphere DEM simulations. Presentation at the American Institute of Chemical Engineers Conference, Philadelphia, PA, USA (November 2008).

67. Discrete element simulations of a Freeman powder rheometer: a study of particle property effects. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Atlanta, GA, USA (November 2008).

68. Development of a material sparing method to determine powder permeability to air. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Atlanta, GA, USA (November 2008).

69. Discrete element simulation (DEM) study of a Freeman powder rheometer. Poster presentation at the American Association of Pharmaceutical Scientists North Eastern Regional Discussion group, Rocky Hill, CT, USA (April 2009).

70. DEM simulations of cylindrical particles – contact detection algorithms and validation studies. Presentation at the American Institute of Chemical Engineers Conference, Nashville, TN, USA (November 2009).

71. The diametral compression test as a strength prediction method for pharmaceutical compacts. Presentation at the American Institute of Chemical Engineers Conference, Nashville, TN, USA (November 2009).

72. Characterization of pharmaceutical powders modified by dry coating. Presentation at the American Institute of Chemical Engineers Conference, Nashville, TN, USA (November 2009).

73. Effect of column height and diameter on minimum fluidization velocity. Presentation at the American Institute of Chemical Engineers Conference, Nashville, TN, USA (November 2009).

74. Evaluation of powder mixing and residence time distributions in a rotary tablet press feed chute and feed frame as a function of compression process parameters. Poster presentation at the American Association of Pharmaceutical Scientists Advances and Opportunities in Drug Product Manufacturing Conference, Baltimore, MD, USA (September 2010).

75. Optimizing the design of eccentric feed hopper for tablet presses using DEM. Presentation at the American Institute of Chemical Engineers Conference, Salt Lake City, UT, USA (November 2010).

76. Classifying the fluidization and segregation behavior of binary mixtures using particle size and density ratios. Presentation at the American Institute of Chemical Engineers Conference, Salt Lake City, UT, USA (November 2010).

77. Compaction of binary particle mixtures using the multi-particle finite element method (MPFEM)" Presentation at the American Institute of Chemical Engineers Conference, Salt Lake City, UT, USA (November 2010).

78. Discrete element modeling of bi-convex tablet shaped particles - contact detection algorithms and validation. Presentation at the American Institute of Chemical Engineers Conference, Salt Lake City, UT, USA (November 2010).

79. Comparison of various models for dilute turbulent gas-particle flow with inelastic collisions and turbulence modulation. Presentation at the American Institute of Chemical Engineers Conference, Salt Lake City, UT, USA (November 2010).

80. Predicting high shear wet milling behavior of pharmaceutical solids. Poster presentation at the American Association of Pharmaceutical Scientists Conference, New Orleans, LA, USA (November 2010).

81. Segregation tests on a directly compressible blend as a tool to evaluate potential content uniformity problems. Poster presentation at the American Association of Pharmaceutical Scientists Conference, New Orleans, LA, USA (November 2010).

82. Rational design and scale-up of batch lubrication processes for immediate release formulations. Poster presentation at the American Association of Pharmaceutical Scientists North Eastern Regional Discussion group, Rocky Hill, CT, USA (April 2011).

83. In-die ultrasonic and off-line air coupled monitoring and characterization techniques for drug tablets, Review of Progress in Quantitative Non-Destructive Evaluation Conference, Burlington, Vermont, USA (July 2011) http://dx.doi.org/10.1063/1.4716416.

84. Effect of particle shape on pharmaceutical and granular flow processes. Presentation at the Particle Processes in the Pharmaceutical Industry Conference, Gold Coast, Australia (July 2011).

85. Real-time ultrasonic compaction monitoring and characterization of drug tablets. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Washington, DC, USA (October 2011).

86. Direct measurement of the unconfined yield stress (UYS) of moderately compressed pharmaceutical powders. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Washington, DC, USA (October 2011).

87. Rational design and scale-up of batch lubrication processes for immediate release formulations. Poster presentation at the American Association of Pharmaceutical Scientists Conference, Washington, DC, USA (October 2011).

88. Rational design and scale-up of batch lubrication processes for immediate release formulations. Presentation at the American Institute of Chemical Engineers Conference, Minneapolis, MN, USA (October 2011).

89. Analysis of non-linear tensile strength variation in binary mixtures using multi-particle finite element method (MPFEM). Presentation at the American Institute of Chemical Engineers Conference, Minneapolis, MN, USA (October 2011).

90. A numerical study of granular shear flows of rod-like particles using the discrete element method. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

91. Powder lubrication in a continuous mixing process. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

92. A QbD approach for scale up and technology transfer of pharmaceutical blending processes. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

93. Parametric analysis of the effects of particle properties on the granular flows of cylindrical particles. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

94. Modeling the dynamics of sphero-cylindrical particles in a vertical axis mixer. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

95. Particle jamming in the gap between a mixing blade and a container. Presentation at the American Institute of Chemical Engineers Conference, Pittsburgh, PA, USA (October 2012).

96. Particle jamming in the gap between a blade and a boundary in a granular mixer. Presentation at the American Physical Society Meeting, Baltimore, MD, USA (April 2013).

97. Discrete element modeling of granular shear flows and breakage of flexible fibers. Presentation at DEM6 Conference, Golden, CO, USA (August 2013).