2017 - Present

1. Yun EJ, Kim D, Kim S, Hsieh JT, Baek ST*. Targeting Wnt/β-catenin-mediated upregulation of oncogenic NLGN3 suppresses cancer stem cells in glioblastoma. Cell Death & Disease. 2023 Jul 13;14(7):423.

2. Ko B, Yoo JY, Yoo T, Choi W, Dogan R, Sung K, Um D, Lee SB, Kim HJ, Lee S, Baek ST, Park SK, Paik SB, Kim TK, Kim JH*. Npas4-mediated dopaminergic regulation of safety memory consolidation. Cell Reports. 2023 Jun 27;42(7):112678.

3. Kim SH, Kwon SS, Park MR, Lee HA, Kim JH, Cha J, Kim S, Baek ST, Kim SH, Lee JS, Kim HD, Choi JR, Lee ST*, Kang HC*. Detecting low-variant allele frequency mosaic pathogenic variants of NF1, TSC2, and AKT3 genes from blood in patients with neurodevelopmental disorders. Journal of Molecular Diagnostics. 2023 Apr 22;S1525-1578(23)00080-6.

4. Mun DJ, Goo BS, Suh BK, Hong JH, Woo Y, Kim SJ, Kim S, Lee SB, Won Y, Yoo JY, Cho E, Jang EJ, Nhung TTM, Triet HM, An H, Lee H, Nguyen MD, Park SY, Baek ST, Park SK*. Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2214507120.

5. Goo BS, Mun DJ, Kim S, Nhung TTM, Lee SB, Woo Y, Kim SJ, Suh BK, Park SJ, Lee HE, Park K, Jang H, Rah JC, Yoon KJ, Baek ST, Park SY, Park SK*. Schizophrenia-associated Mitotic Arrest Deficient-1 (MAD1) regulates the polarity of migrating neurons in the developing neocortex. Molecular Psychiatry. 2023 Feb;28(2):856-870.

6. Kim YE, Kim YS, Lee HE, So KH, Choe Y, Suh BC, Kim JH, Park SK, Mathern GW, Gleeson JG, Rah JC*, and Baek ST*. Reversibility and developmental neuropathology of linear nevus sebaceous syndrome caused by dysregulation of the RAS-MAPK pathway. Cell Reports 2023 Jan 31;42(1):112003.

7. Kim SY, Lee S, Woo H, Han J, Ko YJ, Shim Y, Park S, Jang SS, Lim BC, Ko JM, Kim KJ, Cho A, Kim H, Hwang H, Choi JE, Kim MJ, Moon J, Seong MW, Park SS, Choi SA, Lee JE, Kwon YS, Sohn YB, Kim JS, Kim WS, Lee YJ, Kwon S, Kim YO, Kook H, Cho YG, Cheon CK, Kang KS, Song MR, Kim YJ, Cha HJ, Choi HJ, Kee Y, Park SG, Baek ST, Choi M, Ryu DS, Chae JH.* The Korean Undiagnosed Diseases Program Phase I: Expansion of the Nationwide Network and the Development of Long-term Infrastructures. Orphanet Journal of Rare Disease. 2022 Oct 8;17(1):372. 

8. Yun EJ*, Kim DH, Hsieh JT, Baek ST*. Stanniocalcin 2 drives malignant transformation of human glioblastoma cells by targeting SNAI2 and Matrix Metalloproteinases. Cell Death Discovery. 2022 Jul 5;8:308.

9. Lee S, Nam M, Lee AR, Baek ST, Kim MJ, Kim JS, Kong AH, Lee M, Lee SJ, Kim SY, Kim DU, Hoe KL. Knockdown of vps54 aggravates tamoxifen-induced cytotoxicity in fission yeast. Genomics & Informatics. 2021 Dec;19(4):e39.

10. Yun EJ*, Kim S, Hsieh JT, Baek ST*. Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma. Cell Death & Disease. 2020 Sep 17;11:771.

11. Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, Moncada C, Shipony Z, Linker SB, Marchetto MCN, Gage FH, Chen D, Sultan T, Zaki MS, Ranish JA, Miyakawa T, Luo L, Malenka RC, Crabtree GR, Gleeson JG*. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proc Natl Acad Sci. 2020 May 5;117(18):10055-10066.

12. Woo Y, Kim SJ, Suh BK, Kwak Y, Jung HJ, Nhung TTM, Mun DJ, Hong JH, Noh SJ, Kim S, Lee A, Baek ST, Nguyen MD, Choe Y, Park SK*. Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis. Elife. 2019 Dec 9;8:e50850.

13. Kim YE and Baek ST*. Neurodevelopmental Aspects of RASopathies. Mol Cells. 2019 Jun 30;42(6):441-447.

14. Yun EJ, Lin CJ, Dang A, Hernandez E, Guo J, Chen WM, Allison J, Kim N, Kapur P, Brugarolas J, Wu K, He D, Lai CH, Lin H, Saha D, Baek ST*, Chen BPC*, Hsieh JT*. Down-regulation of human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation. Clinical Cancer Research. 2019 Jul 15;25(14):4542-4551.

15. Schaffer AE, Breuss MW, Caglayan AO, Al-Sanaa N, Al-Abdulwahed HY, Kaymakçalan H, Yılmaz C, Zaki MS, Rosti RO, Copeland B, Baek ST, Musaev D, Scott EC, Ben-Omran T, Kariminejad A, Kayserili H, Mojahedi F, Kara M, Cai N, Silhavy JL, Elsharif S, Fenercioglu E, Barshop BA, Kara B, Wang R, Stanley V, James KN, Nachnani R, Kalur A, Megahed H, Incecik F, Danda S, Alanay Y, Faqeih E, Melikishvili G, Mansour L, Miller I, Sukhudyan B, Chelly J, Dobyns WB, Bilguvar K, Jamra RA, Gunel M, Gleeson JG*. Bi-allelic loss of human CTNNA2, encoding alphaN-catenin, leads to ARP2/3 over-activity and disordered cortical neuronal migration. Nature Genetics. 2018 Aug;50(8):1093-1101.

2013 - 2016

1. Baek ST, Copeland B, Yun EJ, Kwon SK, Guemez-Gamboa A, Schaffer AE, Kim S, Kang HC, Song S, Mathern GW, Gleeson JG*. AnAKT3-FOXG1-Reelin Network Underlies Defective Migration in Human Focal Malformations of Cortical Development. Nature Medicine. 2015 Dec;21(12):1445-54.

2. Kang HC, Baek ST, Song S, Gleeson JG*. Clinical and genetic aspects of the segmental overgrowth spectrum due to somatic mutations in PIK3CA. Journal of Pediatrics. 2015 Nov;167(5):957-62.

3. Conti V, Pantaleo M, Barba C, Baroni G, Mei D, Buccoliero AM, Giglio S, Giordano F, Baek ST, Gleeson JG, Guerrini R*. Focal dysplasia of the cerebral cortex and infantile spasms associated with somatic 1q21.1-q44 duplication including the AKT3 gene. Clinical Genetics. 2015 Sep;88(3):241-7.

4. Yun EJ, Baek ST, Xie D, Tseng SF, Dobin T, Zhang L, Sun H, Xiao G, He D, Kittler R, Hernandez E, Zhou J, Yang J, Hsieh JT*. DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1. Oncogene. 2015 May 21;34(21):2741-52.

5. Baek ST*, Kerjan G*, Bielas SL, Lee JE, Fenstermaker AG, Novarino G, Gleeson JG*. Off-Target Effect of doublecortin Family shRNA on Neuronal Migration Associated with Endogenous MicroRNA Dysregulation. Neuron. 2014 Jun 18;82(6):1255-62. (* equal contribution)

6. Novarino G, Baek ST, Gleeson JG*. The sacred disease: the puzzling genetics of epileptic disorders. Neuron. 2013 Oct 2;80(1):9-11.

7. Baek ST, Gibbs EM, Gleeson JG and Mathern GW*. Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders. Current Opinion in Neurology. 2013 Apr;26(2):122-7.

2007 - 2012

1. Acharya A, Baek ST*, Huang G*, Eskiocak B, Goetsch S, Sung CY, Banfi S, Sauer MF, Olsen GS, Duffield JS, Olson EN, Tallquist MD*. The bhlhtranscription factor Tcf21, is required for lineage-specific EMT of cardiac fibroblastprogenitors. Development. 2012 Jun;139(12):2139-2149. (* equal contribution) [Research Highlight. Development. 2012]

2. Baek ST and Tallquist MD*. Nf1limits epicardial derivative expansion by regulating epithelial to mesenchymaltransition and proliferation. Development. 2012 Jun;139(11):2040-2049.

3. Smith CL, Baek ST, Sung CY, Tallquist MD*. Epicardial-derived cell epithelial to mesenchymaltransition and fate specification require PDGF receptor signaling. Circulation Research. 2011 Jun 10;108(12):e15-26. [Best Manuscript Award. Circ Res. 2011]

4. Acharya A, Baek ST, Banfi S, Eskiocak B, Tallquist MD*. Efficient inducible Cre-mediatedrecombination in Tcf21 cell lineages in the heart and kidney. Genesis. 2011 Nov;49(11):870-722.

5. Kim DU, Hayles J, Kim D, Wood V, Park HO, Won M, Yoo HS, Duhig T, Nam M, Palmer G, Han S, Jeffery L, Baek ST, Lee H, Shim YS, Lee M, Kim L, Heo KS, Noh EJ, Lee AR, Jang YJ, Chung KS, Choi SJ, Park JY, Park Y, Kim HM, Park SK, Park HJ, Kang EJ, Kim HB, Kang HS, Park HM, Kim K, Song K, Song KB, Nurse P*, Hoe KL*. Analysis of a genome-wide set of gene deletions in thefission yeast Schizosaccharomyces pombe. Nature Biotechnology. 2010 Jun;28(6):617-23.

6. Heo KS, Ryoo SW, Kim L, Nam M, Baek ST, Lee H, Lee AR, Park SK, Park Y, Myung CS, Kim DU, Hoe KL*. Cl(-)-Channel Is Essential ForLDL-induced Cell Proliferation via the Activation of Erk1/2 and PI3K/Akt andthe Upregulation of Egr-1 in Human Aortic Smooth Muscle Cells. Mol Cells. 2008 Nov 30;26(5):468-73.

7. Heo KS, Kim DU, Kim L, Nam M, Baek ST, Park SK, Pak Y, Myung CS, Hwang SO, Hoe KL*. Activationof PKCbeta(II) and PKCtheta is essential for LDL-induced cell proliferation ofhuman aortic smooth muscle cells via Gi-mediated Erk1/2 activation and Egr-1upregulation. Biochem Biophys Res Commun. 2008 Mar 28;368(1):126-31.

8. Baek ST, Han S, Nam M, Kim YD, Lee HJ, Heo KS, Lee H, Ahn SK, Lee M, Park SK, Maeng PJ, Park Y, Lee S, Kim DU, Kim D, Hoe KL*. Genome-wide Identification of Haploinsufficiency in FissionYeast. J Microbiol Biotechnol. 2008 Jun;18(6):1059-63.

9. Baek ST, Kim DU, Han S, Woo IS, Nam M, Kim L, Heo KS, Lee H, Hwang H, Choi SJ, Won M, Lee M, Park SK, Lee S, Kwon HJ, Maeng PJ, Park HM, Park Y, Kim D, Hoe KL*. Genome-wide drug-induced haploinsufficientscreening of fission yeast for identification of hydrazinocurcumin targets. J Microbiol Biotechnol. 2008 Feb;18(2):263-9.

10. Heo KS, Kim DU, Ryoo S, Nam M, Baek ST, Kim L, Park SK, Myung CS, Hoe KL*. PPARgamma activation abolishes LDL-inducedproliferation of human aortic smooth muscle cells via SOD-mediateddown-regulation of superoxide. Biochem Biophys Res Commun. 2007 Aug 10;359(4):1017-23