Plant cells use a network of signaling pathways to translate information from endogenous programs and environmental conditions into changes in growth or identity. We use the model plant Arabidopsis thaliana to dissect the regulatory mechanisms allowing plants to fine tune signaling pathways underlying endogenous (hormones) and exogenous cues (soil nutrient concentrations, light, temperature) to create robust responses integrating several signals and regulatory levels

Integrated control of plant growth and development

The Vert Lab is more specifically interested in 1) understanding how plants uses the post-translational modification ubiquitination to control the localization and abundance of intrinsic plasma membrane proteins in response to developmental and environmental cues, and 2) in unraveling the networks of ubiquitination and discovering new proteasome-independent roles for ubiquitination using plants as model. To do so, we use a combination of molecular genetics, high-resolution imaging and proteomics to characterize the machinery driving lysine(K)63-linked polyubiquitin chain formation and its role in plant cells.

For further information on our activities, research developments and projects please follow the links :

1. Role(s) of K63 polyubiquitination in receptor or transporter endocytosis and responses to environmental conditions

2. Regulatory networks driving K63 polyubiquitin chain formation and identification of new roles

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Location

The Vert lab is established since summer 2018 in the beautiful city of Toulouse. The lab now belongs to the Plant Biology Laboratory-LRSV located on the INRA campus of Auzeville-Tolosane. The LRSV gathers 8 research groups and >100 people that develop both basic and applied science to better understand plant growth, development and interactions with their biotic and abiotic environment. The campus also comprises other institutes dedicated to plants (LIPM, GBF, CNRGV), as well as top-notch imaging, proteomic, genomic, plant growth and phenotyping facilities.