Thank you for visiting!

I am a Ph.D. student in biostatistics at UCLA, working in Marc Suchard's group. Before coming to UCLA, I received my bachelor's degree from Department of Biomedical Engineering at Peking University, China in 2016.

Contact me at: zy.zhang[at]ucla.edu

Research

My research interest is in Bayesian inference and computation with applications to phylogenetics (the study of evolutionary relationships among species, genes, etc). In phylogenetics, the observations are correlated via the shared evolutionary history of individuals and highly complex models are required to control for the underlying phylogenetic tree structure. I enjoy developing efficient inference methods to deal with the computational challenges arising from these complex models. All our works are implemented in the widely used BEAST software.

Phylogenetic tree for 535 HIV viruses.

Current Project - Efficient Inference for Phylogenetic Multivariate Probit Models

We develop a new computation approach for inferring correlation among binary and continuous biological features, while controlling for the uncertain phylogenetic tree. Compared to previous studies we reduce the complexity from quadratic to linear order in sample size. In one application, we examine the correlation among 25 HIV epitopes and virulence measures across 535 viruses.

Invited talk at BISP 11th, Madrid, Spain, June 12-14, 2019 & BayesComp 2020, in Gainesville, Florida, January 7-10, 2020

Joint work with : Akihiko Nishimura, Xiang Ji, Paul Bastide, Philippe Lemey

Shennongjia, Hubei Province, China