Cone-beam CT provides volumetric three-dimensional (3D) images, which visualizes distinctive volumetric and morphological information of interal body structure.

Tomosynthesis imaging system provides cross-sectional images from a finite number of projection views within a limited data acquisition range.

Spectral CT utilizes multiple energy spectrum of X-ray to enable material decomposition, and can increase the contrast of medical images while enabling noise reduction.

MTF represents the ratio of the output modulation to the input modulation.

Quantitative metric describing the resolution performance of X-ray based medical imaging system.

Quantitative metric describing the noise including correlation introduced by filtering and other processing steps.

Evaluate lesion detection performance of medical imaging system using human or mathematical models mimicking the human visual system.

For large cone angles, cone beam projection causes the lack of information in frequency space.

To reduce the cone beam artifacts, iterative reconstruction with total variation regularization was proposed.

When the object changes during CT scanning, this motion induces blurring and streak artifacts.

The motion artifacts are corrected by the estimation of rotational and translational motion.

Metal materials can cause metal artifact and degrade image quality.

To correct the artifacts, we developed a metal artifact reduction algorithm by using an edge preserving filter.