Education and Experience / 學經歷

2021-Now Attending physician, Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan. / 台北慈濟醫院 急診部主治醫師

2017-2021 Resident, Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan. / 台北慈濟醫院 急診部住院醫師

2016-2017 Post Graduate Year program, Department of general medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan. / 台北慈濟醫院 畢業後一般醫學訓練

2009-2016 M.D. College of Medicine, Tzu-Chi Medical University, Taiwan. / 慈濟大學醫學系醫學士

In emergency medicine, emergency physicians are responsible for initiating resuscitation, stabilization, early diagnosis, timely interventions and treat illnesses in the acute phase. As first-line providers, emergency physicians requires knowledge and skills, including critical care medicine for shock, anesthesia for difficult airway, cardiology for acute coronary syndrome, neurology for strokes, obstetrics and gynecology for pregnancy and vaginal bleeding, radiology for image studies. Several rare and life-threatening diseases challenge the emergency physicians due to the atypical symptoms, sign, and imaging findings. To prevent the catastrophic clinical outcome, we focused on the pathophysiology and detailed mechanism from bench to bedside to provide a strong foundation for developing novel diagnostic tool and effective therapies.

Carcinogenesis is a complex, multiple step process, involving several mechanisms that mediate cell proliferation, differentiation, apoptosis, epithelial-to-mesenchymal transition, and angiogenesis. Following chronic injury, gene mutations, accumulation of oxidative stress, and local inflammation lead to cell proliferation, differentiation, apoptosis, and necrosis. The persistence of this vicious cycle in turn leads to further gene mutation and dysregulation of pro- and anti-inflammatory cytokines, resulting in immune escape and trigger carcinogenesis. Our goal is to discover principles of signal transduction and to study their role in the maintenance of human health, in aging, and in the development of malignancy. To understand organizing principles of carcinogenesis, we integrate knowledge from oncobiology, oncometabolism, aging biology, and mitochondrial medicine. Our experimental systems include complimentary human, cellular, and animal models.