We need experiments and we need them earlier rather than later. But rats live five or more years, and rats are not people, (as opposed, oft-times, to the other way around). Over the counter metformin is over a decade away, if ever, and buy rapamycin is too dangerous to become street legal in any time, dimension or reality. Metformin, when used with growth hormone to mechanistically force the system to toggle back and forth between neogenesis and regenesis could ultimately turn out to be the greatest anti-aging plus rejuvenation achievement of all time. This could truly cause cells to behave more like they do in the juvenile stage. The timing, dosage and testing required in such a scenario would be critical. This is playing with some real big mojo, here, and it would be illegal without a prescription under a doctor's care. Only people, at least in their early middle years, say past thirty, could participate in such a program, safely.