UPREGAIN
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PARTNERS AND COLLABORATORS
INSTITUTIONS
The main goal of the UpReGain project is to conduct a pilot study on stroke patients to design, develop, and evaluate innovative and personalized rehabilitation strategies that combine brain-computer interfaces, virtual reality, and a robotic hand exoskeleton, focusing on the upper limbs of post-stroke patients.
Main Tasks
Task 1: Design of suitable experimental protocols for robot-assisted therapy.
Task 2: Development of machine learning algorithms to automatically detect the MI.
Task 3: Design and implementation of virtual reality scenarios.
Task 4: Validation of the developed methods and protocols
Funding Information:
Financed by the Foundation for Science and Technology (FCT), 2023.13809.PEX.
Duration: 2025-02-13 to 2026-08-12 Budget: 49.999,83€ DOI: https://doi.org/10.54499/2023.13809.PEX
The UpReGain project is a collaboration between the Institute of Systems and Robotics - University of Coimbra (ISR-UC) and Coimbra Local Health Unit (Unidade Local de Saúde de Coimbra / Polo Centro de Medicina de Reabilitação da Região Centro – Rovisco Pais).
We are very happy to announce that our BCI4ALL@ISR team from HCMR Lab achieved 3rd place at the BCI Hackathon 2026 in the “BCI Programming Projects” category! Congratulations to Luís Garrote, Aniana Cruz, Gonçalo Barros, Eduardo Borges, Manuel Abreu, Nicoli Leal, Sofia Rosa, and Rute Bettencourt, with support from João Perdiz.
The UpReGain project took part in the 3rd Edition of IEEE TechSolve on April 22, 2026. Aniana Cruz and Paulo Menezes were responsible for the ISR Challenge task.
The UpReGain project participated in the BCI Hackathon 2026 with the HCMR Lab team BCI4ALL@ISR.
Aniana Cruz and Gabriel Pires are Guest Editors of the Sensors special issue (section “Biomedical Sensors”). More information: [Here].
Our paper "Pre-Experiment Resting Baseline Improves Motor Imagery BCI Decoding in a Robotic Hand Rehabilitation Context" has been accepted for publication at the 10th Graz Brain-Computer Interface Conference 2026. Congratulations to the team!
A video demonstration of the UpReGain project was presented during the Lab visit session of BotOlympics 2026.
Aniana Cruz presented the work "Gamified brain-machine interfaces for personalized upper-limb post-stroke rehabilitation" during the Poster Session at the 4th Annual Meeting of CIBIT. Check the program: [Here].
Aniana Cruz participated in the 2nd Portuguese Conference on Brain Stimulation in Psychiatry and Mental Health, held in Coimbra on 18 December 2026. Check the program: [Here].
The UpReGain project has been featured in several Portuguese press, including Observador, SAPO 24 Notícias, HealthNews, and TV Europa.
Aniana Cruz participated in the Congresso Internacional de Enfermagem de Reabilitação 2025, held in Tomar from 4 to 6 December 2026.
We are very happy to announce that the University of Coimbra has published a news article showcasing the UpReGain project (https://noticias.uc.pt/artigos/uc-testa-tecnologia-que-traduz-sinais-cerebrais-em-movimento-fisico-atraves-de-mao-robotica-e-realidade-virtual-no-pos-avc/)!
The UpReGain project participated in the ISR Open Lab Day activities on November 19, contributing to the event’s demonstrations.
Our paper "Optimizing BCI Rehabilitation Protocols for Stroke: Exploring Task Design and Training Duration" has been accepted for publication at the IEEE ENBENG2025 Conference! Congrats to the team, especially to Marko Kuzmanoski!
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