Yoshida K, Hisabori T.
Current Insights into the Redox Regulation Network in Plant Chloroplasts
Plant Cell Physiol. 2023 Jul 17;64(7):704-715.doi: 10.1093/pcp/pcad049.
Tran CM, Mihara S, Yoshida K, Hisabori T.
Cystathionine-β-synthase X proteins negatively regulate NADPH-thioredoxin reductase C activity
Biochem Biophys Res Commun. 2023 Apr 23;653:47-52. doi: 10.1016/j.bbrc.2023.02.055.
Yoshida K, Yokochi Y, Tanaka K, Hisabori T.
The ferredoxin/thioredoxin pathway constitutes an indispensable redox-signaling cascade for light-dependent reduction of chloroplast stromal proteins
J Biol Chem. 2022 Dec;298(12):102650. doi: 10.1016/j.jbc.2022.102650.
Fukui K, Yoshida K, Yokochi Y, Sekiguchi T, Wakabayashi KI, Hisabori T, Mihara S.
The Importance of the C-Terminal Cys Pair of Phosphoribulokinase in Phototrophs in Thioredoxin-Dependent Regulation
Plant Cell Physiol. 2022 Jun 15;63(6):855-868. doi: 10.1093/pcp/pcac050.
Fukushi Y, Yokochi Y, Wakabayashi KI, Yoshida K, Hisabori T.
Verification of the Relationship between Redox Regulation of Thioredoxin Target Proteins and Their Proximity to Thylakoid Membranes
Antioxidants (Basel). 2022 Apr 13;11(4):773. doi: 10.3390/antiox11040773.
Yokochi Y, Fukushi Y, Wakabayashi KI, Yoshida K, Hisabori T.
Oxidative regulation of chloroplast enzymes by thioredoxin and thioredoxin-like proteins in Arabidopsis thaliana.
Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2114952118
Deschoenmaeker F, Mihara S, Niwa T, Taguchi H, Wakabayashi KI, Toyoshima M, Shimizu H, Hisabori T.
Thioredoxin pathway in anabaena sp. PCC 7120: activity of NADPH-thioredoxin reductase C
J Biochem. 2021 Feb 4:mvab014. doi: 10.1093/jb/mvab014.
Yokochi Y, Yoshida K, Hahn F, Miyagi A, Wakabayashi KI, Kawai-Yamada M, Weber APM, Hisabori T.
Redox regulation of NADP-malate dehydrogenase is vital for land plants under fluctuating light environment
Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2016903118. doi: 10.1073/pnas.2016903118.
Yoshida K, Hisabori T.
Biochemical basis for redox regulation of chloroplast-localized phosphofructokinase from Arabidopsis thaliana
Plant Cell Physiol. 2021 Jan 8:pcaa174. doi: 10.1093/pcp/pcaa174.
Juniar L, Tanaka H, Yoshida K, Hisabori T, Kurisu G.
Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity
Protein Sci. 2020 Dec;29(12):2538-2545. doi: 10.1002/pro.3964.
Yoshida K, Ohtaka K, Hirai MY, Hisabori T.
Biochemical insight into redox regulation of plastidial 3-phosphoglycerate dehydrogenase from Arabidopsis thaliana
J Biol Chem. 2020 Oct 30;295(44):14906-14915. doi: 10.1074/jbc.RA120.014263.
Sugiura K, Mihara S, Fu N, Hisabori T.
Real-time monitoring of the in vivo redox state transition using the ratiometric redox state sensor protein FROG/B
Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16019-16026. doi: 10.1073/pnas.1918919117.
Mihara S, Sugiura K, Yoshida K, Hisabori T.
Thioredoxin targets are regulated in heterocysts of cyanobacterium Anabaena sp. PCC 7120 in a light-independent manner
J Exp Bot. 2020 Mar 25;71(6):2018-2027. doi: 10.1093/jxb/erz561.
Yoshida K, Yokochi Y, Hisabori T.
New Light on Chloroplast Redox Regulation: Molecular Mechanism of Protein Thiol Oxidation
Front Plant Sci. 2019 Nov 22;10:1534. doi: 10.3389/fpls.2019.01534.
Yokochi Y, Sugiura K, Takemura K, Yoshida K, Hara S, Wakabayashi KI, Kitao A, Hisabori T.
Impact of key residues within chloroplast thioredoxin- f on recognition for reduction and oxidation of target proteins
J Biol Chem. 2019 Nov 15;294(46):17437-17450. doi: 10.1074/jbc.RA119.010401.
Sugiura K, Yokochi Y, Fu N, Fukaya Y, Yoshida K, Mihara S, Hisabori T.
The thioredoxin (Trx) redox-state sensor protein can visualize Trx activities in the light-dark response in chloroplasts.
J Biol Chem. 2019 Jun 19. pii: jbc.RA119.007616. doi: 10.1074/jbc.RA119.007616.
Yoshida K, Uchikoshi E, Hara S, Hisabori T.
Thioredoxin-like2/2-Cys peroxiredoxin redox cascade acts as oxidative activator of glucose-6-phosphate dehydrogenase in chloroplasts.
Biochem J. 2019 Jun 26;476(12):1781-1790. doi: 10.1042/BCJ20190336.
Deschoenmaeker FDR, Mihara S, Niwa T, Taguchi H, Nomata J, Wakabayashi KI, Hisabori T.
Disruption of the Gene trx-m1 Impedes the Growth of Anabaena sp. PCC 7120 under Nitrogen Starvation.
Plant Cell Physiol. 2019 Jul 1;60(7):1504-1513. doi: 10.1093/pcp/pcz056.
Yoshida K, Hisabori T.
Determining the Rate-Limiting Step for Light-Responsive Redox Regulation in Chloroplasts.
Antioxidants (Basel). 2018 Oct 31;7(11). pii: E153. doi: 10.3390/antiox7110153.
Yoshida K, Hara A, Sugiura K, Fukaya Y, Hisabori T.
Thioredoxin-like2/2-Cys peroxiredoxin redox cascade supports oxidative thiol modulation in chloroplasts.
Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8296-E8304. doi: 10.1073/pnas.1808284115.
Deschoenmaeker F, Mihara S, Niwa T, Taguchi H, Wakabayashi KI, Hisabori T.
The Absence of Thioredoxin m1 and Thioredoxin C in Anabaena sp. PCC 7120 Leads to Oxidative Stress.
Plant Cell Physiol. 2018 Dec 1;59(12):2432-2441. doi: 10.1093/pcp/pcy163.
Mihara S, Wakao H, Yoshida K, Higo A, Sugiura K, Tsuchiya A, Nomata J, Wakabayashi KI, Hisabori T.
Thioredoxin regulates G6PDH activity by changing redox states of OpcA in the nitrogen-fixing cyanobacterium Anabaena sp. PCC 7120.
Biochem J. 2017 Apr 4;474(8):1347-1360. doi: 10.1042/BCJ20161089.
Yoshida K, Hisabori T.
Distinct electron transfer from ferredoxin-thioredoxin reductase to multiple thioredoxin isoforms in chloroplasts.
Biochem J. 2017 Apr 4;474(8):1347-1360. doi: 10.1042/BCJ20161089.
Mihara S, Yoshida K, Higo A, Hisabori T.
Functional Significance of NADPH-Thioredoxin Reductase C in the Antioxidant Defense System of Cyanobacterium Anabaena sp. PCC 7120.
Plant Cell Physiol. 2017 Jan 1;58(1):86-94. doi: 10.1093/pcp/pcw182.
Yoshida K, Hisabori T.
Two distinct redox cascades cooperatively regulate chloroplast functions and sustain plant viability.
Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3967-76. doi: 10.1073/pnas.1604101113.
Yutthanasirikul R, Nagano T, Jimbo H, Hihara Y, Kanamori T, Ueda T, Haruyama T, Konno H, Yoshida K, Hisabori T, Nishiyama Y.
Oxidation of a Cysteine Residue in Elongation Factor EF-Tu Reversibly Inhibits Translation in the Cyanobacterium Synechocystis sp. PCC 6803.
J Biol Chem. 2016 Mar 11;291(11):5860-70. doi:10.1074/jbc.M115.706424.
Sugiura K, Nagai T, Nakano M, Ichinose H, Nakabayashi T, Ohta N, Hisabori T.
Redox sensor proteins for highly sensitive direct imaging of intracellular redox state.
Biochem Biophys Res Commun. 2015 Feb 13;457(3):242-8. doi:10.1016/j.bbrc.2014.12.095.
Hara S, Tatenaka Y, Ohuchi Y, Hisabori T.
Direct determination of the redox status of cysteine residues in proteins in vivo.
Biochem Biophys Res Commun. 2015 Jan 2;456(1):339-43. doi: 10.1016/j.bbrc.2014.11.082.
Yoshida K, Matsuoka Y, Hara S, Konno H, Hisabori T.
Distinct redox behaviors of chloroplast thiol enzymes and their relationships with photosynthetic electron transport in Arabidopsis thaliana.
Plant Cell Physiol. 2014 Aug;55(8):1415-25. doi: 10.1093/pcp/pcu066.
Nomata J, Maeda M, Isu A, Inoue K, Hisabori T.
Involvement of thioredoxin on the scaffold activity of NifU in heterocyst cells of the diazotrophic cyanobacterium Anabaena sp. strain PCC 7120.
J Biochem. 2015 Sep;158(3):253-61. doi: 10.1093/jb/mvv046.
Yoshida K, Hara S, Hisabori T.
Thioredoxin Selectivity for Thiol-based Redox Regulation of Target Proteins in Chloroplasts.
J Biol Chem. 2015 Jun 5;290(23):14278-88. doi: 10.1074/jbc.M115.647545.
Kadowaki T, Nishiyama Y, Hisabori T, Hihara Y.
Identification of OmpR-family response regulators interacting with thioredoxin in the Cyanobacterium Synechocystis sp. PCC 6803.
PLoS One. 2015 Apr 13;10(4):e0124571. doi: 10.1371/journal.pone.0124571.
Nagano T, Yutthanasirikul R, Hihara Y, Hisabori T, Kanamori T, Takeuchi N, Ueda T, Nishiyama Y.
Oxidation of translation factor EF-G transiently retards the translational elongation cycle in Escherichia coli.
J Biochem. 2015 Aug;158(2):165-72. doi: 10.1093/jb/mvv026.
Yoshida K, Hisabori T.
Adenine nucleotide-dependent and redox-independent control of mitochondrial malate dehydrogenase activity in Arabidopsis thaliana.
Biochim Biophys Acta. 2016 Mar 3. pii: S0005-2728(16)30047-0. doi:10.1016/j.bbabio.2016.03.001.
Yutthanasirikul R, Nagano T, Jimbo H, Hihara Y, Kanamori T, Ueda T, Haruyama T, Konno H, Yoshida K, Hisabori T, Nishiyama Y.
Oxidation of a Cysteine Residue in Elongation Factor EF-Tu Reversibly Inhibits Translation in the Cyanobacterium Synechocystis sp. PCC 6803.
J Biol Chem. 2016 Mar 11;291(11):5860-70. doi:10.1074/jbc.M115.706424.
Hara S, Tatenaka Y, Ohuchi Y, Hisabori T.
Direct determination of the redox status of cysteine residues in proteins in vivo. Biochem Biophys Res Commun. 2015 Jan 2;456(1):339-43. doi: 10.1016/j.bbrc.2014.11.082. Epub 2014 Nov 28.
Yoshida K, Matsuoka Y, Hara S, Konno H, Hisabori T.
Distinct redox behaviors of chloroplast thiol enzymes and their relationships with photosynthetic electron transport in Arabidopsis thaliana. Plant Cell Physiol. 2014 Aug;55(8):1415-25. doi: 10.1093/pcp/pcu066. Epub 2014 May 20.
Hara S., Hisabori T.
Kinetic analysis of the interactions between plant thioredoxin and target proteins.
Front Plant Sci. 2013 Dec 18;4:508. doi: 10.3389/fpls.2013.00508. eCollection 2013.
Ueoka-Nakanishi H, Sazuka T, Nakanishi Y, Maeshima M, Mori H, Hisabori T.
Thioredoxin-h Regulates Calcium Dependent Protein Kinases in Plasma Membranes.
FEBS J. 2013 Jul;280(14):3220-31. doi: 10.1111/febs.12301. Epub 2013 Jun 14.
Yoshida K, Noguchi K, Motohashi K, Hisabori T.
Systematic Exploration of Thioredoxin Target Proteins in Plant Mitochondria.
Plant Cell Physiol. 2013 Jun;54(6):875-92. doi: 10.1093/pcp/pct037. Epub 2013 Feb 26.
Tsukamoto Y, Fukushima Y, Hara S, Hisabori T.
Redox control of the activity of phosphoglycerate kinase in Synechocystis sp. PCC6803.
Plant Cell Physiol. 2013 Apr;54(4):484-91. doi: 10.1093/pcp/pct002. Epub 2013 Jan 7
Hara S, Nojima T, Seio K, Yoshida M, Hisabori T.
DNA-maleimide: An improved maleimide compound for electrophoresis-based titration of reactive thiols in a specific protein.
Biochim Biophys Acta. 2013 Apr;1830(4):3077-81. doi: 10.1016/j.bbagen.2013.01.012. Epub 2013 Jan 26.
Nagano T, Kojima K, Hisabori T, Hayashi H, Morita EH, Kanamori T, Miyagi T, Ueda T, Nishiyama Y.
Elongation factor G is a critical target during oxidative damage to the translation system of Escherichia coli.
J Biol Chem. 2012 Aug 17;287(34):28697-704. doi: 10.1074/jbc.M112.378067. Epub 2012 Jul 6.
Kikutani S, Tanaka R, Yamazaki Y, Hara S, Hisabori T, Kroth PG, Matsuda Y.
Redox regulation of carbonic anhydrases via thioredoxin in chloroplast of the marine diatom Phaeodactylum tricornutum.
J Biol Chem. 2012 Jun 8;287(24):20689-700. doi: 10.1074/jbc.M111.322743. Epub 2012 Apr 25.
Horiuchi M, Nakamura K, Kojima K, Nishiyama Y, Hatakeyama W, Hisabori T, Hihara Y.
The PedR transcriptional regulator interacts with thioredoxin to connect photosynthesis with gene expression in cyanobacteria.
Biochem J. 2010 Oct 1;431(1):135-40.
Motohashi K, Hisabori T.
CcdA is a thylakoid membrane protein required for the transfer of reducing equivalents from stroma to thylakoid lumen in the higher plant chloroplast.
Antioxid Redox Signal. 2010 Mar 9. [Epub ahead of print]
Kojima K, Motohashi K, Morota T, Oshita M, Hisabori T, Hayashi H, Nishiyama Y.
Regulation of translation by the redox state of elongation factor G in the cyanobacterium Synechocystis sp. PCC 6803.
J Biol Chem. 2009 Jul 10;284(28):18685-91. Epub 2009 May 15.
Motohashi K, Romano PG, Hisabori T.
Identification of thioredoxin targeted proteins using thioredoxin single cysteine mutant-immobilized resin.
Methods Mol Biol. 2009;479:117-31.
Kobayashi K, Mochizuki N, Yoshimura N, Motohashi K, Hisabori T, Masuda T.
Functional analysis of Arabidopsis thaliana isoforms of the Mg-chelatase CHLI subunit.
Photochem Photobiol Sci. 2008 Oct;7(10):1188-95. Epub 2008 Jun 9.
Naomi Hosoya-Matsuda, Kazuhito Inoue, and Toru Hisabori
Roles of Thioredoxins in the Obligate Anaerobic Green Sulfur Photosynthetic Bacterium Chlorobaculum tepidum
Mol Plant , March 2009; 2: 336 - 343
Hishiya, S., Hatakeyama, W., Mizota, Y., Hosoya-Matsuda, N., Motohashi, K., Ikeuchi, M., Hisabori, T.
Binary reducing equivalent pathways using NADPH-thioredoxin reductase and ferredoxin-thioredoxin reductase in the cyanobacterium Synechocystis sp. strain PCC 6803
Plant Cell Physiol. 2008 49(1):11-8. Epub 2007 Nov 14
Wakita M, Masuda S, Motohashi K, Hisabori T, Ohta H, Takamiya KI.
The significance of type II and PrxQ peroxiredoxins for antioxidative stress response in the purple bacterium rhodobacter sphaeroides.
J Biol Chem. 2007 Sep 21;282(38):27792-801, Jul 20; [Epub ahead of print]
Ikegami A, Yoshimura N, Motohashi K, Takahashi S, Romano PG, Hisabori T, Takamiya K, Masuda T.
The CHLI1 subunit of Arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin.
J Biol Chem. 2007 Jul 6;282(27):19282-91.
Motohashi K, Hisabori T.
HCF164 receives the reducing equivalents from stroma thioredoxin across thylakoid membrane and mediates reduction of target proteins in thylakoid lumen.
J Biol Chem . 2006 281(46):35039-35047.
Hara S, Motohashi K, Arisaka F, Romano PG, Hosoya-Matsuda N, Kikuchi N, Fusada N, Hisabori T.
Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants.
J Biol Chem . 2006 281(43):32065-32071.
Yamaryo T, Motohashi K, Takamiya K., Hisabori T, Ohta H.(2006)
In vitro reconstitution of monogalactosyldiacylglycerol (MGDG) synthase regulation by thioredoxin
FEBS Lett. 580, 4086-4090
Hisabori T, Motohashi K, Hosoya-Matsuda N, Ueoka-Nakanishi H, Romano PG.
Towards a Functional Dissection of Thioredoxin Networks in Plant Cells.
Photochem Photobiol. 2007 Jan-Feb;83(1):145-51.
Epub ahead of print]
Hisabori, T., Hara, S., Fujii, T., Yamazaki, D., Hosoya-Matusda, N., Motohashi, K., (2005)
Thioredoxin affinity chromatography: a useful method for further understanding the thioredoxin network
J Exp. Bot. 56(416):1463-8
Hosoya-Matusda, N., Motohashi, K., Yoshimura, H., Nozaki, A., Inoue, K., Ohmori, M., Hisabori, T. (2005)
Anti-oxidative stress system in cyanobacteria: Significance of type II peroxiredoxin and the role of 1-Cys peroxiredoxin in Synechocystis sp. strain PCC 680
J Biol Chem. 280 (1), 840-846
Yamazaki, D., Motohashi, K., Kasama, K., Hara, Y., Hisabori, T. (2004)
Target proteins of the cytosolic thioredoxins in Arabidopsis thaliana
Plant Cell Physiol. 45, 18-27
Motohashi, K., Koyama, F., Nakanishi, Y., Ueoka-Nakanishi, H., Hisabori, T. (2003)
Chloroplast cyclophilin is a target protein of thioredoxin: Thiol modulation of the peptidyl-prolyl cis-trans isomerase activity
J. Biol. Chem . 278, 31848-31852
Saze, H., Ueno, Y., Hisabori, T., Hayashi, H., Izui, K. (2001)
Thioredoxn-mediated reductive activation of a protein kinase for the regulatory phosphorylation of C4-form phosphoenolpyruvate carboxylase from maize.
Plant Cell Physiol. 42, 1295-1302
Motohashi, K., Kondoh, A., Stumpp, M. T., Hisabori, T. (2001)
Comprehensive survey of proteins targeted by chloroplast thioredoxin
Proc. Natl. Acad. Sci. USA , 98, 11224-11229