Light-induced protochlorophyllide oxidoreductase (LPOR) is an essential enzyme along the chlorophyll synthesis pathway. It employs red photons, absorbed by the chlorophyll precursor substrate (pChlide), to perform a stereospecific reduction.
We are aiming to first solve the static structure of LPOR, to be followed with dynamical XFEL experiments. Many interesting questions about the mechanism of LPOR remain unanswered without the help of a guiding structure. We are excited to be tackling this challenging system.
Imperial College London
Univ of Gothenburg
Lewis and Clark College