Highlighted Research Articles
Muscle Innervation
Injection of VEGF + IGF-1 releasing alginate hydrogels into injured or transplanted muscle improved muscle function. (Green, neurons; red, motor end plates in muscle tissue 50 days following nerve injury and treatment with VEGF + IGF-1 alginate)
Functional Recovery with Nanoparticle Directed Macrophage Polarization
IL-4 Gold nanoparticles dampen the inflammatory response and promote a pro-healing macrophage phenotype that improves muscle regeneration and strength following injury.
DNA-Functionalized Beads for Microfluidic In Vitro Transcription
Integrated microfluidic devices for the purification, amplification, and detection of nucleic acids are a prevalent area of research. Here, we analyze the effects of solution composition, microchannel, and bead hydrophobicity on DNA-functionalized bead adhesion and in vitro transcription reactions.
Press Releases
A golden ticket to faster muscle recovery
Nanoparticles of gold covered with cytokines reduce inflammation and promote the regeneration of muscle fibers
Harnessing the immune response to improve functional healing
Science Translational Medicine
Editor's Choice
Interleukin-4–conjugated gold nanoparticles promote M2 macrophage polarization and functional muscle recovery in an ischemic mouse model.