Theresa Raimondo, PhD

Muscle Innervation

Injection of VEGF + IGF-1 releasing alginate hydrogels into injured or transplanted muscle improved muscle function. (Green, neurons; red, motor end plates in muscle tissue 50 days following nerve injury and treatment with VEGF + IGF-1 alginate)

Functional Recovery with Nanoparticle Directed Macrophage Polarization

IL-4 Gold nanoparticles dampen the inflammatory response and promote a pro-healing macrophage phenotype that improves muscle regeneration and strength following injury.

DNA-Functionalized Beads for Microfluidic In Vitro Transcription

Integrated microfluidic devices for the purification, amplification, and detection of nucleic acids are a prevalent area of research. Here, we analyze the effects of solution composition, microchannel, and bead hydrophobicity on DNA-functionalized bead adhesion and in vitro transcription reactions.

Science Translational Medicine

Editor's Choice

Interleukin-4–conjugated gold nanoparticles promote M2 macrophage polarization and functional muscle recovery in an ischemic mouse model.