The Deans Lab for Applied Synthetic Biology
Welcome to the Deans Lab for Applied Synthetic Biology! The central focus of our lab is to better understand hematopoietic stem cell (HSC) self-renewal and differentiation for the purpose of directing their differentiation to mass-produce platelets and red blood cells in vitro, in addition to using them as novel therapeutic delivery devices.
Based upon the need for improved tools to better understand and to direct stem cell fate to be used for therapeutic applications, our lab has three synergistic focus groups to study hematopoietic stem cell (HSC) fate decisions: (1) Build novel genetic tools to control the contributions of intrinsic cues on HSC proliferation and differentiation (synthetic biology), (2) Engineer biomimetic microenvironments and genetically interactive biomaterials to control the extrinsic cues on HSC proliferation and differentiation (coupling synthetic biology with biomaterials), and (3) Engineer cells to deliver therapeutic biomolecules to sites of injury and/or disease (synthetic biology).
Follow us on twitter: @genegirl007
December 2018 - Celebratory lunch for Luke and Connor passing their PhD qualifying exam!
November 2018 - Jonathan Emmons joins the lab! Welcome Jonathan!!
October 2018 - Chelsea had a busy day presenting her poster! #BMES2018
October 2018 - Connor killing it at his poster! #BMES2018
October 2018 - A very BIG congratulations to Connor and Luke for passing their PhD qualifying exam!
August 2018 - Connor Healy received the Kathy Phelps Equality Education Fund scholarship! Congratulations Connor!
August 2018 - Congratulations Dr. Fitzgerald! Mike successfully defends his PhD!!
Dr. Fitzgerald with Dr. Deans
August 2018 - Jenna Langford was awarded UROP funding! Congratulations to Jenna for getting her Undergraduate Research Opportunity Program (UROP) award renewed for her project titled: "Characterization of the hematopoietic stem cell microenvironment."
June 2018 - Chelsea Gibbs received the Glenn E. Nielson Memorial Endowed Scholarship for the 2018/2019 academic year. Congratulations Chelsea!
May 2018 - Travis Seamons joins the lab! Welcome Travis!
May 2018 - Jenna Langford was awarded UROP funding! Congratulations to Jenna for being awarded the Undergraduate Research Opportunity Program (UROP) award for her project titled: "Characterization of the hematopoietic stem cell microenvironment."
March 2018 - Mitch's review, "Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications" is out!