The aim of this research is to develop artificial bone and cartilage tissues by 3D bioprinting for treating various orthopedic conditions such as rheumatoid arthritis, paget’s disease, broken bones, fractures and other injuries to the joint due to cartilage degradation. We believe that the artificially printed tissues would be able to replace the natural tissues which are damaged by disease, accident or injury.
The recent developments of 3D bioprinting technology and tissue engineering techniques are making massive advancements in the development of implantable artificial tissue scaffolds & constructs. Since the tissues contain the patient’s own DNA, the chances of tissue rejection are minimal. The precise use of biomaterials and CAD designing would allow the construction of tissues that mimics the native tissues of the body. However, vascularization of the tissues after implanting is a major area of concern. Thus, it is a promising aspect to construct bone and cartilage tissue scaffolds to treat complex orthopedic conditions successfully in the near future.
Contributions:
Idea generation, literature review, formulating research questions, writing the original draft manuscript, and curation of visualisations and tables
Tanvir Ahmed1, Kazi Tasnuva Alam1, Zarin Tasnim Tisha1, Humyra Nahalin1, Farhana Akter1, Md. Jasim Uddin2*
1Drug Delivery & Therapeutics Lab, IG2 6TT, London, UK
2Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
*Corresponding author
Md. Jasim Uddin
January 2021–December 2021