TaccLab
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Professor Cristian Taccioli Laboratory
Bioinformatics Laboratory
Not living physical systems are simple, and naturally contain little information, whereas life on earth is extremely complex. However, the second law of thermodynamics lead us to expect great uniformity (disorder) or maximum entropy. My group is trying to investigate this nature ambiguity linking biology, thermodynamics and theory of information. We are also interested in using Next Generation techniques when studying the genome of normal and tumor cells of animal models.
DNA, or deoxyribonucleic acid, is the genetic material of all the living organisms. It contains information able to pass information from a generation to another. This information is stored in a code of for nitrogenous bases: adenine (A), guanine (G), cytosine (C), and thymine (T). Human DNA consists of about 3 billion bases for each of the two strands of the double helix, and only 2% of DNA code for proteins that are the bricks of living cells. The rules that regulating, however, the vast complexity of living organisms are still unknown. Most of the topics of "Tacclab" is focused on investigating genomic evolution, comparative and cancer genomics. For a list of forthcoming articles, see below.