Srinivasa Reddy Bonam, M. Pharmacy (Pharmacology), PhD.
Senior Scientist,
Vaccine Immunology Laboratory, Department of Applied Biology,
CSIR-Indian Institute of Chemical Technology
Ministry of Science and Technology, Govt of India,
Tarnaka, Hyderabad-500007, Telangana State, India.
Mobile: +91 9014399199
Email: bonamsr.iict@csir.res.in; bsrpharmacy90@gmail.com
ORCiD: 0000-0002-2888-2418
Listed in the Top 2% of scientists: 2024, 2023, 2022, 2021
Our work published in "Science" was featured in several media.
Listed in the Top 2% Scientists
07/2024 – Present: Senior Scientist, Vaccine Immunology Laboratory, Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Ministry of Science and Technology, Govt of India, Tarnaka, Hyderabad-500007, Telangana State, India.
09/2023 – 04/2024: Instructor, Department of Microbiology & Immunology, University of Texas Medical Branch (UTMB), Galveston, TX, USA.
04/2022 – 08/2023: Postdoctoral Fellow IV in the Department of Microbiology & Immunology at the UTMB, 301 University Blvd, Galveston, Texas 77550, USA.
06/2020 – 03/2022: Postdoc at INSERM, Centre de Recherche des Cordeliers, Paris, France.
04/2018 – 02/2020: Postdoc at Ecole supérieure de biotechnologie de Strasbourg, University of Strasbourg, France.
03/2013 – 01/2018: PhD at CSIR-Indian Institute of Chemical Technology, Hyderabad, India. Link
01/2011 – 03/2013: M. Pharmacy, Pharmacology at Chalapathi Institute of Pharmaceutical Sciences, Guntur, India.
04/2007 – 12/2011: B. Pharm Pharmaceutical Sciences at Chalapathi Institute of Pharmaceutical Sciences, Guntur, India
CSIR Startup grant: Developing a versatile mRNA-LNP platform for treating emerging and re-emerging infectious diseases and protein-based therapies. From 01/09/2024 to 28/02/2026. Grant number: CSIR-IICT/BDRM/Startupgrant/24-26/10
Ignite Life Science Foundation: Expanding Therapeutic Horizons: A Self-Amplifying mRNA-LNP Platform for Protein Therapeutics. From 2024-12 to 2025-12. Grant number: Acorn-AMR3/RNATech/2024/01
Prime Minister Early Career Research Grant: Revolutionizing Inflammation Control: mRNA-LNP-Driven TNFα Antibodies for Treating Inflammatory Bowel Disease. Grant number: ANRF/ECRG/2024/000505/LS
Marie Curie Fellowship: MedTrain+ Marie Skłodowksa Curie Fellowship Program 2023, Horizon Europe’s Marie Skłodowska-Curie Actions at the CÚRAM Centre, University of Galway, Ireland in the group of Prof. Matthew Griffin/Prof. Abhay Pandit. Self-denied.
Served as a scientific evaluator at the 33rd Keck Annual Research Conference, New Frontiers in RNA Biology & Therapeutics at the Bioscience Research Collaborative (BRC) building, Houston, Texas, USA organized by Gulf Coast Consortia.
Prestigious “BHARAT SHIKSHA GAURAV PURASKAR” and a “CERTIFICATE OF EDUCATION EXCELLENCE” for outstanding achievements and remarkable contributions in the field of Pharmaceutical Education. Ref: BSGP/APR/2023, 2023 by KTK Outstanding Achievers and Education Foundation, New Delhi.
Adjunct associate professor at Bapatla College of Pharmacy (Bapatla College Rd, S.N.P. Agraharam, Bapatla, Andhra Pradesh 522101) from 01/2022 to 01/2025.
Professional development committee member in Society for Leukocyte Biology
CEFIPRA travel grant for attending the one-day conference, “Week 26, INNOVATION DAY sustainable health” at the University of Bordeaux, June 28/2017, France.
CIPS-American Association of Pharmaceutical Scientist’s (AAPS) Financial support for registration and national travel to present a poster on January 4-7 at IPSCON-2012, Nagpur, India.
Best paper presentation, 2011 in B. Pharmacy IV year on Vaccines, in college-level seminars.
Qualified Graduate Pharmacy Aptitude Test (GPAT–2011 Pharmaceutical Sciences) conducted by Human Resources Development Ministry, Govt. of India in collaboration with M.S. University, Baroda, Vadodara-390001, India.
Registered pharmacist in India.
US-9,969,763 - 1,2,3-triazole-tethered carbohydrate-di and tri lipidated cysteine conjugates useful as novel vaccine adjuvants and methods for the preparation thereof. Sampath Kumar Halmuthur Mahabalarao, Nalla Naresh, Surya Vamshi Sathyaseelan, Sathyabama, Sabbana, Srinivasa Reddy Bonam, Naveen Kumar Veerjala. Granted-2018-05-15.
IN201811042595 (Application number) - An uttroside saponin based immune-adjuvant/potentiator composition and process for preparation thereof (product patent). Halmuthur Mahabalarao Sampath Kumar, Bonam Srinivasa Reddy, Lankalapalli Ravishankar. CSIR-IICT & NIIST collaborative invention. Recently filed in India (IPC: C12N 15/82).
Mohamad-Gabriel Alameh, Alexa Semon, Nile U. Bayard, Yi-Gen Pan, Garima Dwivedi, James Knox, Rochelle C. Glover, Paula C. Rangel, Ceylan Tanes, Kyle Bittinger, Qianxuan She, Haitao Hu, Srinivasa Reddy Bonam, Jeffrey R. Maslanka, Paul J. Planet, Ahmed M. Moustafa, Benjamin Davis, Anik Chevrier, Mitchell Beattie, Houping Ni, Gabrielle Blizard, Emma E. Furth, Robert H. Mach, Marc Lavertu, Mark A. Sellmyer, Ying Tam, Michael C. Abt, Drew Weissman, and Joseph P. Zackular "A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection." Science 386, no. 6717 (2024): 69-75. IF: 50.03
Hajnik Renee L#, Jessica A. Plante#, Srinivasa Reddy Bonam#, Grace H. Rafael, Yuejin Liang, Nicholas C. Hazell, Jordyn Walker et al. "Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants." npj Vaccines 9, no. 1 (2024): 1-12. IF: 6.9
Srinivasa Reddy Bonam*, Nicholas C. Hazell, Mano Joseph Mathew, Yuejin Liang, Xuxiang Zhang, Zhi Wei, Mohamad-Gabriel Alameh, Drew Weissman, and Haitao Hu*. "Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice." Vaccines 12, no. 5 (2024): 543. IF: 7.8
Zhongfeng Ye#, Srinivasa Reddy Bonam#, Lindsay GA McKay, Jessica A. Plante, Jordyn Walker, Yu Zhao, Changfeng Huang et al. "Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants." Proceedings of the National Academy of Sciences 120, no. 52 (2023): e2311752120. IF: 11.1
Renee L. Hajnik, Jessica A. Plante, Yuejin Liang, Mohamad-Gabriel Alameh, Jinyi Tang, Srinivasa Reddy Bonam, Chaojie Zhong, Awadalkareem Adam, Dionna Scharton, Grace H. Rafael, Yang Liu, Nicholas C. Hazell, Jiaren Sun, Lynn Soong, Pei-Yong Shi, Tian Wang, David H. Walker, Jie Sun, Drew Weissman, Scott C. Weaver, Kenneth S. Plante, Haitao Hu. "Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models." Science Translational Medicine. 2022: eabq1945. IF: 19.31
Srinivasa Reddy Bonam, Peter Paul Platenburg, and Jagadeesh BAYRY. "Retrospective analysis on the immunopotentiating mechanism of an emulsion-based vaccine adjuvant on human antigen-presenting cells." Frontiers in Immunology 13: 7738. IF: 8.78
Srinivasa Reddy Bonam, Camille Chauvin, Mano J. Mathew, Jagadeesh Bayry. IFN-γ induces PD-L1 expression in primed human basophils. Cells 11 (2022), 801. IF: 7.66
Srinivasa Reddy Bonam#, Camille Chauvin#, Laurine Levillayer#, Mano J. Mathew, Anavaj Sakuntabhai and Jagadeesh Bayry. SARS-CoV-2 induces cytokine responses in human basophils. Frontiers in Immunology 13 (2022): 838448. IF: 8.78
Note: Featured at INSERM press on 24 FEB 2022.
Anupama Karnam#, Srinivasa Reddy Bonam#, Naresh Rambabu, Sarah Sze Wah Wong, and Vishu Kumar Aimanianda Bopaiah, Jagadeesh Bayry. Wnt-β-catenin signaling in human dendritic cells mediates regulatory T cell responses to fungi via PD-L1 pathway. mBio. 12 (2021), e02824-21. IF: 7.78
Srinivasa Reddy Bonam, Debabrata Bhunia, Sylviane Muller, Sridhar Goud Nerella, Mallika Alvala, and Sampath Kumar Halmuthur Mahabalarao. "Novel trisaccharide based phospholipids as immunomodulators." International Immunopharmacology 74 (2019): 105684. IF: 4.93
Naresh Rambabu, Fawaz Alzaid, Boban D. Anđelković, Sruthi Vijaya Retnakumar, Anupama Karnam, Srinivasa Reddy Bonam, Lucie Orliaguet, Tina Ejlalmanesh, Dorothy Tonui, Emeline Chu-Van, Ludovic Brunet, Nina Bozinovic, Ivan Nemazanyy, Fabian Käsermann, Nicolas Venteclef, Srini V. Kaveri, Thibaut Léger, François Fenaille, Benoit Colsch, Jagadeesh Bayry. “Regulation of immune cell metabolism by therapeutic normal IgG intravenous immunoglobulin.” Journal of Allergy and Clinical Immunology (2025): In press. IF: 11.10
K. Swetha, Anushree Bhatnagar, Manikrishna Lakavathu, Penta Poornima, Pratiksha Ganesh, Adithi Kamath, Srinivasa Reddy Bonam, Srinivasa M. Srinivasula and Rajendra Kurapati. “Biological Degradation of Graphitic Carbon Nitride Sheets and Autophagy Induction in Macrophages.” Nanoscale (2025): In press. IF: 5.80.
Swati Tirunal Achary, Prerna Gupta, Apoorva Rajput, Wanphidabet Sohkhia, Srinivasa Reddy Bonam*, Bidya Dhar Sahu*. "Phytochemicals Targeting Inflammatory Pathways in Alcohol-Induced Liver Disease: A Mechanistic Review". Pharmaceuticals 18, no. 5: 710. IF: 4.30.
Nicholas C. Hazell, Rachel A. Reyna, Srinivasa Reddy Bonam, Jiani Bei, Naveen Kumar, Tina N. Nguyen, Jessica A. Plante et al. "mRNA-delivered neutralizing antibodies confer protection against SARS-CoV-2 variant in the lower and upper respiratory tract." bioRxiv (2025): 2025-04.
Jasneet Kaur, K. Swetha, Manjot Singh, Avazbek Abduvakhidov, Michela Varra, Manikrishna Lakavathu, Jaber Adam, Anjali Prajapati, Srinivasa Reddy Bonam, Carlo Altucci, Rajendra Kurapati. "Functionalization dependent biodegradability of two-dimensional antimonene by peroxidases: impact on immune modulation." Nanoscale 17 (2025): 11293-11304. IF: 5.80. Covered on the front page.
Ankita Chakraborty, Dr Nabarun Chandra Das, Parth Sarthi Sen Gupta, Saroj Kumar Panda, Malay Kumar Rana, Srinivasa Reddy Bonam, Jagadeesh BAYRY, and Suprabhat Mukherjee. "In Silico Evidence of Monkeypox F14 as a Ligand for the Human TLR1/2 Dimer." Frontiers in Immunology 16 (2025): 1544443. IF: 5.70
Mohamad-Gabriel Alameh, Alexa Semon, Nile U. Bayard, Yi-Gen Pan, Garima Dwivedi, James Knox, Rochelle C. Haitao Hu, Srinivasa Reddy Bonam.........Glover et al. "A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection." Science 386, no. 6717 (2024): 69-75. IF: 50.03
Hajnik Renee L#, Jessica A. Plante#, Srinivasa Reddy Bonam#, Grace H. Rafael, Yuejin Liang, Nicholas C. Hazell, Jordyn Walker et al. "Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants." npj Vaccines 9, no. 1 (2024): 1-12. IF: 6.9
Srinivasa Reddy Bonam*, Nicholas C. Hazell, Mano Joseph Mathew, Yuejin Liang, Xuxiang Zhang, Zhi Wei, Mohamad-Gabriel Alameh, Drew Weissman, and Haitao Hu*. "Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice." Vaccines 12, no. 5 (2024): 543. IF: 7.8
Momitul Ahmed, Pavithra Kurungottu, K. Swetha, Sandeep Atla, Nivethitha Ashok, Easa Naga Malleswari, Srinivasa Reddy Bonam*, Bidya Dhar Sahu*, and Rajendra Kurapati*. "Role of NLRP3 Inflammasome in Nanoparticle Adjuvant-Mediated Immune Response." Biomaterials Science (2024). Accepted. IF: 6.6. Covered on the front page.
Shinde, Divya P., Jordyn Walker, Rachel A. Reyna, Dionna Scharton, Brooke Mitchell, Ennid Dulaney, Srinivisa Reddy Bonam, Haitao Hu, Jessica A. Plante, Kenneth S. Plante, and et al. "Mechanisms of Flavivirus Cross-Protection against Yellow Fever in a Mouse Model." Viruses 16, no. 6 (2024): 836. IF: 4.6
Ananth Kumar Kammala, Madhuri Tatiparthy, Tilu Jain Thomas, Srinivasa Reddy Bonam, Istvan Boldogh, Hu Haitao, Surendra Sharma, and Ramkumar Menon. "In vitro mRNA‐S maternal vaccination induced altered immune regulation at the maternal‐fetal interface." American Journal of Reproductive Immunology 91, no. 5 (2024): e13861. IF: 3.6
Zhongfeng Ye#, Srinivasa Reddy Bonam#, Lindsay GA McKay, Jessica A. Plante, Jordyn Walker, Yu Zhao, Changfeng Huang et al. "Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants." Proceedings of the National Academy of Sciences 120, no. 52 (2023): e2311752120. IF: 11.1
Srinivasa Reddy Bonam#, Dylan Mastrippolito#, Philippe Georgel and Sylviane Muller. "Pharmacological targets at the autophagy-NLRP3 inflammasome crossroads". Trends in Pharmacological Sciences 45, no. 1 (2024): 81-101. IF: 13.8; Covered on the front page.
Abdul Q Rani, Srinivasa Reddy Bonam, Jia Zhou, Jenny Li, Haitao Hu, and Xuefeng Liu. "BRD4 as a potential target for human papillomaviruses associated cancer." Journal of Medical Virology 95, no. 12 (2023): e29294. IF: 12.1
Saksena K. Nitin, Srinivasa Reddy Bonam, Monica Miranda-Saksena, Thyago HS Cardoso, Edson MA Silva, Juliana C. Fereira, and Wael M. Rabeh. "SARS-CoV-2 variants, its recombinants and epigenomic exploitation of host defenses." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease (2023): 166836. IF: 6.2
Nadia M. Hamdy, Lisardo Bosca, Sukh Mahendra Singh, Srinivasa Reddy Bonam, Igor Kiss, Divya P. Kumar, and Aditi Banerjee. "Women in gastrointestinal cancers, volume II: 2022." Frontiers in Oncology 13 (2023): 1192814. IF: 4.7
Srinivasa Reddy Bonam and Haitao Hu. "Next-Generation Vaccines against COVID-19 Variants: Beyond the Spike Protein." Zoonoses 3, no. 1 (2023). IF: New journal
Chetan Ram, Shobhit Gairola, Shobhit Verma, Madhav Nilakanth Mugale, Srinivasa Reddy Bonam, Upadhyayula Suryanarayana Murty, and Bidya Dhar Sahu. "Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis." Antioxidants 12, no. 5 (2023): 1052. IF: 7.67
Carole El Hachem, Pierre Marschall, Pierre Hener, Anupama Karnam, Srinivasa Reddy Bonam, Pierre Meyer, Eric Flatter, Marie-Christine Birling, Jagadeesh Bayry, and Li Mei. "IL-3 produced by T cells is crucial for basophil extravasation in hapten-induced allergic contact dermatitis." Frontiers in Immunology 14 (2023): 1990. IF: 8.78
Srinivasa Reddy Bonam, Peter Paul Platenburg, and Jagadeesh Bayry. "Retrospective analysis on the immunopotentiating mechanism of an emulsion-based vaccine adjuvant on human antigen presenting cells." Frontiers in Immunology 13 (2023): 1086752. IF: 8.78
Camille Chauvin, Laurine Levillayer, Mathilde Roumier, Hubert Nielly, Claude Roth, Anupama Karnam, Srinivasa Reddy Bonam et al. "Tocilizumab-treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants." Iscience 26, no. 3 (2023). IF: 6.10
K. Swetha, Niranjan G. Kotla, Lakshmi Tunki, Arya Jayaraj, Suresh K. Bhargava, Haitao Hu, Srinivasa Reddy Bonam*, and Rajendra Kurapati*. "Recent Advances in the Lipid Nanoparticle-Mediated Delivery of mRNA Vaccines." Vaccines 11, no. 3 (2023): 658. IF: 4.96
Nitin K. Saksena, Pedro A. Reche, Srinivasa Reddy Bonam, and Nicasio Mancini. "Innate immune responses to SARS-CoV-2 in infected and vaccinated individuals." Frontiers in Immunology 16648714 (2023): 6. IF: 8.78
Sruthi Vijaya Retnakumar, Srinivasa Reddy Bonam, Haitao Hu, and Jagadeesh Bayry. "THEME:“Vaccines and Vaccine Adjuvants/Immunomodulators for Infectious Diseases”." Vaccines 11, no. 2 (2023): 383. IF: 4.96
Renee L. Hajnik, Jessica A. Plante, Yuejin Liang, Mohamad-Gabriel Alameh, Jinyi Tang, Srinivasa Reddy Bonam, Chaojie Zhong, Awadalkareem Adam, Dionna Scharton, Grace H. Rafael, Yang Liu, Nicholas C. Hazell, Jiaren Sun, Lynn Soong, Pei-Yong Shi, Tian Wang, David H. Walker, Jie Sun, Drew Weissman, Scott C. Weaver, Kenneth S. Plante, Haitao Hu. "Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models." Science Translational Medicine. 2022: eabq1945. IF: 19.31
Srinivasa Reddy Bonam, Haitao Hu, and Jagadeesh Bayry. "Role of the PD-1 and PD-L1 axis in COVID-19." Future Microbiology 17, no. 13 (2022): 985-988. IF: 3.55
Srinivasa Reddy Bonam, Camille Chauvin, Mano J. Mathew, Jagadeesh Bayry. "IFN-γ induces PD-L1 expression in primed human basophils." Cells 11 (2022), 801. IF: 7.66
Srinivasa Reddy Bonam#, Camille Chauvin#, Laurine Levillayer#, Mano J. Mathew, Anavaj Sakuntabhai and Jagadeesh Bayry. "SARS-CoV-2 induces cytokine responses in human basophils." Frontiers in Immunology 13 (2022): 838448. IF: 8.78
Note: Featured at INSERM press on 24 FEB 2022.
Anupama Karnam#, Srinivasa Reddy Bonam#, Naresh Rambabu, Sarah Sze Wah Wong, and Vishu Kumar Aimanianda Bopaiah, Jagadeesh Bayry. "Wnt-β-catenin signaling in human dendritic cells mediates regulatory T cell responses to fungi via PD-L1 pathway." mBio. 12 (2021), e02824-21. IF: 7.78
Srinivasa Reddy Bonam, Christine Tranchant, and Sylviane Muller. "Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease." Cells 10, no. 12 (2021): 3547. IF: 7.66
Srinivasa Reddy Bonam, Mahendran Sekar, Girija S. Guntuku, Sridhar G. Nerella, Krishna M. Pawar A, Siva R. Challa, Gopala KMT Eswara, and Sivamma Mettu. "Role of pharmaceutical sciences in future drug discovery." Future Drug Discovery. 3 (2021): FDD64. IF: New journal
Srinivasa Reddy Bonam*,#, Laurent Rénia*,#, Ganesh Tadepalli, Jagadeesh Bayry, and Halmuthur Mahabalarao Sampath Kumar*. "Plasmodium falciparum malaria vaccines and vaccine adjuvants." Vaccines (MDPI). (2021). IF: 4.96
Ummi Zulaiqha Hamid, Maw Shin Sim, Rhanye Mac Guad, Vetriselvan Subramaniyan, Mahendran Sekar, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker Woon Choy, Ismail Muhamad Fareez, Srinivasa Reddy Bonam and Yuan Seng Wu (2021). "Molecular Regulatory Roles of Long Non-coding RNA HOTTIP: An Overview in Gastrointestinal Cancer." Current Molecular Medicine. 21 (2021) (In press) IF: 3.00.
Kah Min Yap, Mahendran Sekar, Lay Jing Seow, Siew Hua Gan, Srinivasa Reddy Bonam et al. "Mangifera indica (Mango): A promising medicinal plant for breast cancer therapy and understanding its potential mechanisms of action." Breast Cancer: Targets and Therapy. 2021 In press. IF: 1.41
Niranjan Kotla#, Srinivasa Reddy Bonam#, Swetha Rasala#, Jitendra Wankar, Raghvendra A Bohara, Jagadeesh Bayry, Abhay Pandit, Yury Rochev. "Recent advances and prospects of hyaluronan as a multifunctional therapeutic system." Journal of Controlled Release. 336 (2021), 598-620. IF: 9.77.
Saksena N, Srinivasa Reddy Bonam and Miranda-Saksena M. "Immunopathogenesis of SARS-CoV-2- Evolving knowledge and its current status." Exploration of Immunology. 2021. In press. IF: New journal
Maud Wilhelm, Srinivasa Reddy Bonam et al. "Implication of a lysosomal antigen in the pathogenesis of lupus erythematosus." Journal of Autoimmunity. 120 (2021): 102633. IF: 14.51
Highlighted in The CFATG (Club Francophone de l’Autophagie, or The Francophone Autophagy Club)
Saksena, Nitin K., Srinivasa Reddy Bonam, and Monica Miranda-Saksena. "Epigenetic Lens to visualize the Severe Acute Respiratory Syndrome coronavirus-2 (SARS-Co-V2) infection in COVID-19 Pandemic." Frontiers in Genetics 12 (2021): 291. IF: 4.77
Shazalyana Azman, Mahendran Sekar, Suzana Wahidin, Siew Hua Gan, Jaishree Vaijanathappa, Srinivasa Reddy Bonam et al. "Embelin Alleviates Severe Airway Inflammation in OVA-LPS-Induced Rat Model of Allergic Asthma." Journal of Asthma and Allergy. 2021: In press. IF: 3.02.
Shazalyana Azman#, Mahendran Sekar#, Srinivasa Reddy Bonam#, et al. "Traditional Herbal Medicines Conferring Protection against Ovalbumin-Induced Asthma in Experimental Animals: A Review." Journal of Asthma and Allergy. 2021: In press. #Equal contribution IF: 3.02.
Nur Sakinah Muhamad Fadzil, Mahendran Sekar, Siew Hua Gan, Srinivasa Reddy Bonam, et al. "Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin - A Promising Natural Lead for New Drug Discovery and Development." Drug Design, Development and Therapy. 2021:In press. IF: 4.31
Lum, Pei Teng, Mahendran Sekar, Siew Hua Gan, Srinivasa Reddy Bonam, and Mohd Farooq Shaikh. "Protective Effect of Natural Products against Huntington’s Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action." ACS Chemical Neuroscience 12 (2021): 391-418. IF: 5.78
Klionsky, Daniel J., …………………… Srinivasa Reddy Bonam et al. "Guidelines for the use and interpretation of assays for monitoring autophagy." Autophagy (2021): 1-382. IF: 13. 39
Srinivasa Reddy Bonam*, Niranjan G. Kotla, Raghvendra A. Bohara, Yury Rochev, Thomas J. Webster, and Jagadeesh Bayry. "Potential immuno-nanomedicine strategies to fight COVID-19 like pulmonary infections." Nano Today. 36 (2020): 101051. IF: 18.96.
Srinivasa Reddy Bonam*, and Sylviane Muller*. "Parkinson's disease is an autoimmune disease: A reappraisal." Autoimmunity Reviews (2020): 102684. IF: 17.39.
Highlighted in the blog: https://journeywithparkinsons.com/2023/01/26/parkinsons-and-autoimmunity/
Lum Pei Teng, Mahendran Sekar, Siew Hua Gan, Vijayapandi Pandy, and Srinivasa Reddy Bonam. "Protective effect of mangiferin on memory impairment: A systematic review." Saudi Journal of Biological Sciences 28 (2020): 917-927. IF: 2.80.
Srinivasa Reddy Bonam*, Sylviane Muller, Jagadeesh Bayry, and Daniel J. Klionsky. "Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine." Autophagy (2020): 1-7. IF: 13.39
Srinivasa Reddy Bonam, Jagadeesh Bayry, Mario P. Tschan, and Sylviane Muller. "Progress and challenges in the use of MAP1LC3 as a legitimate marker for measuring dynamic autophagy in vivo." Cells 9, no. 5 (2020): 1321. IF: 7.66.
Srinivasa Reddy Bonam, Srini V. Kaveri, Anavaj Sakuntabhai, Laurent Gilardin, and Jagadeesh Bayry. "Adjunct immunotherapies for the management of severely Ill COVID-19 patients." Cell Reports Medicine (2020): 100016. IF: 16.98
Guad R. M., V. Subramaniyan, I. M. Fareez, K. W. Choy, Srinivasa Reddy Bonam, C. Selvaraju, M. S. Sim, S. C. B. Gopinath, and Y. S. Wu. "Human Exfoliated Deciduous Teeth Stem Cells: Features and Therapeutic Effects on Neurogenerative and Hepatobiliary-Pancreatic Diseases." Current Stem Cell Research & Therapy (2020). IF: 2.61
Srinivasa Reddy Bonam, and Jagadeesh Bayry. "For antigen-specific effector or Foxp3+ regulatory T cell fate, cyclin-dependent kinases hold the trump card." Cellular & Molecular Immunology 17, no. 4 (2020): 310-312. IF: 22.09. Covered on the front page.
Ramakrishnan Puvanesswaray, Wei Mee Loh, Subash CB Gopinath, Srinivasa Reddy Bonam, Ismail M. Fareez, Rhanye Mac Guad, Maw Shin Sim, and Yuan Seng Wu. "Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer." Acta Pharmaceutica Sinica B 10, no. 3 (2020): 399-413. IF: 14.90
Srinivasa Reddy Bonam, Marc Ruff, and Sylviane Muller. "HSPA8/HSC70 in immune disorders: a molecular rheostat that adjusts chaperone-mediated autophagy substrates." Cells 8, no. 8 (2019): 849. IF: 7.66
Srinivasa Reddy Bonam, Fengjuan Wang, and Sylviane Muller. "Lysosomes as a therapeutic target." Nature Reviews Drug Discovery 18, no. 12 (2019): 923-948. IF: 112.28. Covered on the front page.
Srinivasa Reddy Bonam, Debabrata Bhunia, Sylviane Muller, Sridhar Goud Nerella, Mallika Alvala, and Sampath Kumar Halmuthur Mahabalarao. "Novel trisaccharide based phospholipids as immunomodulators." International Immunopharmacology 74 (2019): 105684. IF: 4.93
Srinivasa Reddy Bonam, Sathish Kumar Manoharan, Vijayapandi Pandy, Anji Reddy Raya, Rama Rao Nadendla, Manjunathan Jagadeesan, and Ankem Narendra Babu. "Phytochemical, in vitro Antioxidant and in vivo Safety Evaluation of Leaf Extracts of Tragia plukenetii." Pharmacognosy Journal 11, no. 2 (2019). Corrigendum [2019,11,4,848]. (IF: Pending).
Sunkari Satish, Srinivasa Reddy Bonam, AV Subba Rao, Sd Riyaz, V. Lakshma Nayak, Halmuthur Mahabalarao Sampath Kumar, Ahmed Kamal, and Bathini Nagendra Babu. "Synthesis and biological evaluation of new bisindole-imidazopyridine hybrids as apoptosis inducers." Bioorganic Chemistry 87 (2019): 484-494. IF: 5.30
Pratap Surya, Fatima Naaz, Srinivasa Reddy Bonam, Kunal K. Jha, Kalicharan Sharma, Dinakar Sahal, Mymoona Akhter et al. "Anti‐proliferative and anti‐malarial activities of spiroisoxazoline analogues of artemisinin." Archiv der Pharmazie 352, no. 1 (2019): 1800192. IF: 3.75
Wang Fengjuan, Srinivasa Reddy Bonam, Nicolas Schall, Lauriane Kuhn, Philippe Hammann, Olivier Chaloin, Jean-Baptiste Madinier, Jean-Paul Briand, Nicolas Page, and Sylviane Muller. "Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival." Scientific Reports 8, no. 1 (2018): 1-12. IF: 4.99
Work featured in European Inventor Award ceremony
Sultana Faria, Srinivasa Reddy Bonam, V. Ganga Reddy, V. Lakshma Nayak, Ravikumar Akunuri, Sunitha Rani Routhu, Abdullah Alarifi, M. Sampath Kumar Halmuthur, and Ahmed Kamal. "Synthesis of benzo [d] imidazo [2, 1-b] thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents." Bioorganic Chemistry 76 (2018): 1-12. [Corrigendum: Bioorganic Chemistry 96 (2020) 1030702]. IF: 5.30
Reddy V. Ganga, Srinivasa Reddy Bonam, T. Srinivasa Reddy, Ravikumar Akunuri, V. G. M. Naidu, V. Lakshma Nayak, Suresh K. Bhargava, HM Sampath Kumar, P. Srihari, and Ahmed Kamal. "4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer." European Journal of Medicinal Chemistry 144 (2018): 595-611. IF: 6.51
Srinivasa Reddy Bonam, Jaggaiah Naidu Gorantla, Arun Kumar Thangarasu, Ravi Shankar Lankalapalli, and Halmuthur Mahabalarao Sampath Kumar. "Polyhydroxy-N-alkyl-2-pyrrolidinones as a new class of glycolipid analogues with immune modulation potential." Journal of Carbohydrate Chemistry 37, no. 1 (2018): 30-43. IF: 1.66
Kantipakala Ravi, Srinivasa Reddy Bonam, Sravanthi Vemireddy, Sreekanth Miryala, and Sampath Kumar Halmuthur M. "Squalane-based emulsion vaccine delivery system: composition with murabutide activate Th1 response." Pharmaceutical Development and Technology 24, no. 3 (2019): 269-275. IF: 2.34
Sultana Faria, Kesari L. Manasa, Siddiq Pasha Shaik, Srinivasa Reddy Bonam, and Ahmed Kamal. "Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent Update." Current Medicinal Chemistry 26, no. 40 (2019): 7212-7280. IF: 3.89
Brun Susana, Nicolas Schall, Srinivasa Reddy Bonam, Kévin Bigaut, Ayikoe-Guy Mensah-Nyagan, Jérôme de Sèze, and Sylviane Muller. "An autophagy-targeting peptide to treat chronic inflammatory demyelinating polyneuropathies." Journal of Autoimmunity 92 (2018): 114-125. IF: 14.51
Srinivasa Reddy Bonam, Yuan Seng Wu, Lakshmi Tunki, Ranjithkumar Chellian, Mahabalarao Sampath Kumar Halmuthur, Sylviane Muller, and Vijayapandi Pandy. "What has come out from phytomedicines and herbal edibles for the treatment of cancer?." ChemMedChem 13, no. 18 (2018): 1854-1872. IF: 3.01
Srinivasa Reddy Bonam, Fengjuan Wang, and Sylviane Muller. "Autophagy: a new concept in autoimmunity regulation and a novel therapeutic option." Journal of Autoimmunity 94 (2018): 16-32. IF: 14.51
Bendorius Mykolas, Indira Neeli, Fengjuan Wang, Srinivasa Reddy Bonam, Eszter Dombi, Nelly Buron, Annie Borgne-Sanchez, Joanna Poulton, Marko Radic, and Sylviane Muller. "The Mitochondrion-lysosome axis in adaptive and innate immunity: Effect of lupus regulator peptide P140 on mitochondria autophagy and NETosis." Frontiers in Immunology 9 (2018): 2158. IF: 8.78
Preethi Pallavi, M. C., D. Bhunia, Srinivasa Reddy Bonam, V. Sravanthi, and H. M. Sampath Kumar. "Novel Mannosylated Synthetic Saponin as Vaccine Adjuvant for Recombinant Japanese Encephalitis Antigen." J Immunol Forecast. 2018; 1 (1) 1002. . (IF: New journal)
Lingamurthy Macha, Gopalal Rao Nalliboina, Maddimsetti Venkateswara Rao, Batchu Venkateswara Rao, Srinivasa Reddy Bonam, and Halmuthur Mahabalarao Sampath Kumar. "DDQ mediated stereoselective intermolecular benzylic CN bond formation: Synthesis of (−)-cytoxazone,(−)-4-epi-cytoxazone and their analogues and immunological evaluation of their cytokine modulating activity." Tetrahedron 73, no. 11 (2017): 1473-1481. IF: 2.37
Chirke Sahadev S., Jattuboyina Siva Krishna, Balaji B. Rathod, Srinivasa Reddy Bonam, Vijay M. Khedkar, Batchu Venkateswara Rao, Halmuthur Mahabalarao Sampath Kumar, and Prakasham Reddy Shetty. "Synthesis of Triazole Derivatives of 9‐Ethyl‐9H‐carbazole and Dibenzo [b, d] furan and Evaluation of Their Antimycobacterial and Immunomodulatory Activity." ChemistrySelect 2, no. 24 (2017): 7309-7318. IF: 2.30
Srinivasa Reddy Bonam, Charalambos D. Partidos, Sampath Kumar M. Halmuthur, and Sylviane Muller. "An overview of novel adjuvants designed for improving vaccine efficacy." Trends in Pharmacological Sciences 38, no. 9 (2017): 771-793. . IF: 17.63, highly cited and blogged Link
Sandeep A#, Srinivasa Reddy Bonam#, Irfan Hyder, and Halmuthur M. Sampath Kumar. "Synthesis of a new class of glycolipids and the evaluation of their immunogenicity using murine splenocytes." Journal of Carbohydrate Chemistry 35, no. 6 (2016): 326-343. IF: 1.66
Verma Yogesh Kumar, Srinivasa Reddy Bonam, Mithun S. Pawar, Debabrata Bhunia, and Halmuthur M. Sampath Kumar. "Design, synthesis, and immunological evaluation of benzyloxyalkyl-substituted 1, 2, 3-triazolyl α-GalCer analogues." ACS Medicinal Chemistry Letters 7, no. 2 (2016): 172-176. IF: 4.63
Sravanthi Vemireddy, MC Preethi Pallavi, Srinivasa Reddy Bonam, Sathyaseelan Sathyabama, and Halmuthur M. Sampath Kumar. "Oleic acid nanoemulsion for nasal vaccination: Impact on adjuvanticity based immune response." Journal of Drug Delivery Science and Technology 28 (2015): 56-63. IF: 5.06
Nalla Naresh, Preethi Pallavi, Srinivasa Reddy Bonam, Sreekanth Miryala, V. Naveen Kumar, Mohammed Mahboob, and M. Sampath Kumar Halmuthur. "Design, synthesis and immunological evaluation of 1, 2, 3-triazole-tethered carbohydrate–Pam3Cys conjugates as TLR2 agonists." Bioorganic & Medicinal Chemistry 23, no. 17 (2015): 5846-5855. IF: 3.46
Bhunia Debabrata, Preethi MC Pallavi, Srinivasa Reddy Bonam, Sandeep A. Reddy, Yogesh Verma, and M. Sampath Kumar Halmuthur. "Design, Synthesis, and Evaluation of Novel 1, 2, 3‐Triazole‐Tethered Glycolipids as Vaccine Adjuvants." Archiv der Pharmazie 348, no. 10 (2015): 689-703. IF: 4.61
Doreddula Sathish Kumar, Srinivasa Reddy Bonam#, Durga Prasad Gaddam, Brahma Srinivasa Rao Desu, Nadendla Ramarao, and Vijayapandi Pandy. "Phytochemical analysis, antioxidant, antistress, and nootropic activities of aqueous and methanolic seed extracts of ladies finger (Abelmoschus esculentus L.) in mice." The Scientific World Journal 2014 (2014). IF: 1.71
Attended IMMUNOCON-2024 as a delegate, 17th to 20th October 2024 at J.N. Tata Auditorium, IISc, Bengaluru organised by the Indian Immunology Society.
4Renee L. Hajnik, Jessica A. Plante, Yuejin Liang, Mohamad-Gabriel Alameh, Jinyi Tang, Srinivasa Reddy Bonam, Nicholas C. Hazell, Tian Wang, David H. Walker, Jie Sun, Drew Weissman, Scott Weaver, Kenneth S. Plante, Haitao Hu. Developing broadly protective mRNA vaccines against SARS-CoV-2. Keystone Symposia, Vaccinology During and After COVID-19. September 17-20, 2023, Atlanta, Georgia, USA.
Srinivasa Reddy Bonam, Camille Chauvin, Laurine Levillayer, Mano Joseph Mathew, Anavaj Sakuntabhai and Jagadeesh Bayry. Basophils orientate immune response to SARS-CoV-2 and IFN-γ. 2nd meeting of the Mast cell-Basophil club, Institute Imagine, Paris, Nov 10th 2023, France. Camille Chauvin presenting author.
Srinivasa Reddy Bonam et al., Blocking nuclear export of HSPA8 after heat shock stress by the autophagy inhibitor P140 severely alters cell survival. 9th Scientific Days on Autophagy, 20-22 November 2019, Strasbourg, France. In association with LS2-Autophagy-Swiss network for autophagy research and GBM Studiengruppe Autophagie.
Srinivasa Reddy Bonam, Sylviane Muller: Week 26, INNOVATION DAY sustainable health, University of Bordeaux, France. 28-June-2017.
Bonam Srinivasa Reddy: Adjuvant effect of glycophospholipid analogues on the immune responses to ovalbumin in mice. 8th Indo Global summit and Expo on Vaccines, Therapeutics & Healthcare (VTH-2015). November 02-04, 2015 HICC, Hyderabad, India.
Bonam Srinivasa Reddy: The Role of Priming Kinase (Ck2) Inhibitor in Caerulein Induced Acute Pancreatitis in Mice. 45th Annual Conference of Indian Pharmacological Society and International Conference on Navigating Pharmacology towards Safe and Effective Therapy, Nagpur; 01/2013.
Bonam Srinivasa Reddy: Effect of levetiracetam (nootropic and neuroprotective agent) on anxiolytic and neuroprotective action of 7-nitroindazole. 45th Annual Conference of Indian Pharmacological Society and International Conference on Navigating Pharmacology towards Safe and Effective Therapy, Nagpur; 01/2013.
Bonam Srinivasa Reddy: Neuroprotective Effects of Leaf Extracts of Tragia Plukenetii R. Smith Using Middle Cerebral Artery Occlusion Model in Rats. 45th Annual Conference of Indian Pharmacological Society and International Conference on Navigating Pharmacology towards Safe and Effective Therapy, Nagpur; 01/2013.
Eitenne Jacotot, Laura Talamini, Srinivasa Reddy Bonam, Angelica Thomaz Vieira, Veronique Fremeaux-Bacchi, Marko Radic, et al., Innate Innate immune responses in COVID-19. Book Title: Autoimmunity, COVID-19, Post-COVID19 syndrome and COVID-19 vaccination. Editors: Y. Shoenfeld. Being published by Elsevier, 2022. Link
Srinivasa Reddy Bonam*, Aparna Areti, Prashanth Komirishetty, Sylviane Muller. Chapter 10 – Dendrimers in immunotherapy and hormone therapy. Book title: Pharmaceutical Applications of Dendrimers. Elsevier, 2020, 233-249. *Corresponding author. Link
Vijayapandi Pandy*, Srinivasa Reddy Bonam*, Anji Reddy Raya, Nadendla Rama Rao. Chapter – Morinda citrifolia Linn. (noni) fruit, antioxidant effects and neuroprotection. Book title - Oxidative Stress and Dietary Antioxidants in Neurological Diseases. Elsevier, 2020, 444. *Corresponding author. Link
Namballa Hari Krishna*, Niranjan G. Kotla*, Philip E. Bourne*, Srinivasa Reddy Bonam*. Successful funding of proposals in the pharmaceutical sciences. Book Title: Principles of Research Methodology and Ethics in Pharmaceutical Sciences, Editors: Vikas Anand Saharan, Hitesh Kulhari, Hemant Jadhav and Ujwal Kolhe. Being published by CRC Press, Taylor & Francis, 2021. *Corresponding author. Link
Mahendran Sekar, Pei Teng Lum, Srinivasa Reddy Bonam, Siew Hua Gan. Chapter 17 – Use of honey in liver disease. Book title: The healing power of Honey and honey products, Editors: Siew Hua Gan & Md. Ibrahim Khalil. Being published by Wiley, 2021. Link
Mahendran Sekar, Pei Teng Lum, Siew Hua Gan, Srinivasa Reddy Bonam. Chapter 22 – Medicinal Benefits of Bee Venom. Book title: The healing power of Honey and honey products, Editors: Siew Hua Gan & Md. Ibrahim Khalil. Being published by Wiley, 2021. Link
Rangolie KAVERI, Fabienne FARCE, Srinivasa Reddy Bonam, Françoise HAU, Dominique BERTRAND. Donor-specific antibodies and their relevance in renal transplantation. Book title: Inflammation. Being published by Chanre journals, 2021.
Invited as a resource person at the one-day national conference on Lab to Life: The Latest Trends in Drug Discovery and Development, organized by the Chennupati Indo-American School of Pharmacy, 15th March 2025. Title of the talk: From Concept to Clinic: The Rise of mRNA-LNP Vaccines. Sponsored by the Katalyst Healthcares & Life Sciences, New Jersey, USA.
Invited as a keynote speaker at the International Conference on Emerging Trends In Personalized Drug Discoveries – A Futuristic Approach, organized by the Vignan Pharmacy College (Autonomous), 31st January 2025. Title of the talk: Harnessing Lipid Nanotechnology for mRNA Applications.
Invited as a keynote speaker at the Pharma NEST5.E, International Conference on Accelerating Drug Discovery and Development Through Artificial Intelligence, organized by the Operant Pharmacy Federation, 30th January 2025. Title of the talk: The Role of Conventional mRNA-LNP Platform in Emerging Disease Preparedness.
Invited as a keynote speaker at An International Symposium on Sustainable Drug Design and Nanoparticle Development: Quantum and Computational Perspectives
Organized by Nirmala College of Pharmacy, Mangalagiri, Guntur, Andhra Pradesh. Title of the talk: From Design to Delivery: Lipid Nanoparticles for mRNA Applications. 22-23, January 2025.
Invited as a speaker to deliver a technical talk on RNA technology by Ignite Life Science Foundation at RNA Technology meeting_25-26 October 2024 at IISc Bengaluru.
Delivered a talk titled "Unlocking Potential: The Versatility of mRNA in Modern Healthcare" at Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India, on 17th August 2024 in commemoration of the birth anniversary of Sri Ram Nath Chopra (Father of Indian Pharmacology).
Invited as an international speaker to deliver a motivational lecture on “Role of A Pharmacist and Opportunities in Research” on the occasion of “World Pharmacists Day” on 25th September at College of Pharmaceutical Sciences and Research, Krishna University, Andhra Pradesh, India.
University of Strasbourg, France, CNRS-Institut de Biologie Moléculaire et Cellulaire (IBMC), Immunopathology and therapeutic chemistry on February 09, 2017 – Development of Novel Vaccine Adjuvants.
Switzerland: Prof. Mario P. Tschan, Ph.D., Institute of Pathology, Division of Experimental Pathology, University of Bern, 3008 Bern, Switzerland. E-mail: mario.tschan@pathology.unibe.ch
Australia: Dr. Nitin Saksena, Ph.D., EPIGENES Australia Pty Ltd, Mooroolbark VIC 3138; and Victoria University, Ballarat Rd, Footscray VIC 3011. Melbourne. Australia. E-mail: nitin.saksena@bigpond.com
Ireland: Prof. Yury Rochev, Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, Galway, H91 W2TY, Ireland. Email: yury.rochev@nuigalway.ie
Malaysia:
Dr. Yuan Seng Wu, Ph.D., Postdoctoral fellow, Department of Biochemistry, Faculty of Medicine and Biomedical Sciences, MAHSA University, Selangor 42610, Malaysia, Tel: Email: sengwu_21@yahoo.com or sywu@mahsa.edu.my
Dr. Mahendran Sekar, Ph.D., Associate Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh - 30450, Perak, Malaysia. Phone no: (6016) – 3346653, Fax: (605) – 2536634. E-mail: mahendransekar@unikl.edu.my
Society for Leukocyte Biology-8093 (2021-present)
Société Française de Biochimie et Biologie Moléculaire/French Society of Biochemistry and Molecular Biology (SFBBM)-2019-2020
DGfI (German Society of Immunology)-4695 – 2018-2020
TCS (The Cytometry Society) of India-L-1370
IIS (Indian Immunology Society)-LM/IIS/592/06/17
IPA (Indian Pharmaceutical Association)-AP/VIJ/LM/0135
STOX (Society of Toxicology)-959L
LASA (Laboratory Animal Scientist’s Association)-9315
IPS (Indian Pharmacological Society)-LR-256
APTI (Association of Pharmaceutical Teachers of India)-TL/LM-815
AAPS (American Association of Pharmaceutical Scientist’s)-216386 (2012-2013)
ASAW (Academy of Sciences for Animal Welfare)
Construction of mRNA vaccines: Target selection, Vector design, PCR, Transformation, Clone section, Purification, In vitro transcription, and Characterization by transfection studies (Western blot, flow cytometry, and microscopy).
Experienced in handling both primary and secondary cell cultures.
Handling small animals (mouse/rats/hamsters), e.g. multiple routes of injections/treatments, necropsies, tissue processing, cell isolation, various routes of blood collection, and others.
Experience in working a Biosafety Level 3 environment. During the pandemic vigorously handled the COVID-19 patient blood samples for further studies.
Experience in basic immunology techniques, such as cell isolation and culture, ELISA; multicolour flow cytometry, cell separation techniques, functional assays and others.
Advanced user of several flow cytometers, such as BD LSR II, BD LSR Fortessa, and BD FAC Symphony A5 SE. Experience in human and rodent immune cells profiling from blood, PBMCs, Splenocytes or bone marrow cells by multicolour flow cytometry.
Immune cell sorting (T cells (including CD8+ T, Naïve CD4+ T cells and memory Tregs, Th-like Tregs [Th1, Th2, Th17, Th1/Th17]), B cells, Monocytes) by column-based separation.
Immune cell differentiation from monocytes to DCs or Macrophages.
Functional assay for blocking and activating T, B, DCs, and Basophils immune checkpoints.
Optimized the CD4+ T cell differentiation (Th1, Th2, Th17 and Tregs) for screening activators and inhibitors for immunomodulation.
Co-culture assays, like, DC-T cells and Basophils-Treg cells.
Experience in basic molecular techniques, such as protein, DNA and RNA extraction from cells and tissues, performing SDS-PAGE, western blot, and PCR, RT-qPCR, primer design.
Scientific data and patent searching and drafting using databases such as SciFinder, PubMed, and others.
Good knowledge of application software's viz., Microsoft office, ChemBioDraw 14.0, GraphPad Prism 8, ImageJ, Image lab and reference management software’s (EndNote, Zotero, Mendeley).
Strong English, written and oral communication skills.
Pasteur Course: Successfully completed the “Regulatory course for project designers (Mice & Lagomorphs)”, on November 2 to 13, 2020, Animalerie Centrale, Institut Pasteur, Paris, France.
ICMR Workshop Trainer: I have acted as a trainer for the ICMR sponsored “Workshop on Experimental Pharmacology” organized at Chalapathi Institute of Pharmaceutical Sciences, on 1st-3rd August 2012, Guntur, India.
Successfully completed BD FACSOrient (BD FACSVerse) a course in Flow Cytometry Basics from 17th – 19th June 2013 at BD-JH FACS Academy, New Delhi, India.
Successfully completed hands-on training and workshop on multicolor flow cytometry, from 1st-3rd December 2014 at the Department of animal biology, University of Hyderabad, India.
Participated in the workshop “Biostatistics and Research methodology” (Biostats 2016), held on 22-24th April 2016 at CIENCIA Research Communications Pvt. Ltd., Hyderabad, India.
Worked as a faculty member while doing masters in a program “earn while you learn” at Chalapthi Institute of Pharmaceuticals sciences for a period of 2 years (2011-2013).
Worked as a part-time faculty member, to teach B.Voc technical courses to Dr.Reddy’s laboratory staff in a program “CEO Skill Foundations private limited (CEOSFPL)-Tata Institute of Social Sciences- School of Vocational Education (TISS-SVE)” at Hyderabad branch for a period of one year (2015-2016).
Workshop on Experimental Pharmacology on 1st to 3rd, August-2012, organized by Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Chalapathi Nagar, Guntur, A.P. Sponsored by Indian Council of Medical Research (ICMR), New Delhi.
Pharma Libitum On 30th March – 2013, organized by Department of Pharmacy Practice & Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Chalapathi Nagar, Guntur, A.P. In Collaboration with CIPS Alumni Association (CIPSAA).
Kesav B. M. Pharmacy (Pharmacology). I trained him for dissertation work over a year on the basic cell culture techniques pertaining to immunology and animal handling techniques.
Gowri Bhavani A. M. Pharmacy (Pharmacology). I trained her dissertation work for over a year on the basic cell culture pertaining to immunology and animal handling techniques.
Murali Krishna A. M.Sc (Biotechnology). I trained him for six months of a research training program on the basic cell culture pertaining to anticancer and animal handling techniques. Present he is a PhD student at IISER, Tirupati, India.
Lucrezia Righelli, Masters 2 (biological sciences). I trained her for six months research training program on cell culture and basic techniques, western blot and immunohistochemistry. Present she is a PhD student at the University of Birmingham, UK.
For correcting the research manuscript
For providing high-resolution figure
For drawing the figures
For help with ELISA assays
For providing technical assistance – Tail vein injections
Last updated 11.05.2025
