Kurzgesagt – In a Nutshell
Sources – Aging Part I
– 50,000 years ago most humans died very young.
#Life expectancy, 2018
https://en.wikipedia.org/wiki/Life_expectancy
– Today humans are living longer and healthier lives than ever before.
#How Science Has Made It Possible for Humans to Live Longer, 2017
http://genolevures.org/science-health/how-science-made-possible-to-live-longer/
#Breaking the Ceiling of Human Maximal Life span, 2018
https://academic.oup.com/biomedgerontology/article/73/11/1465/4602243
– We spend an ever increasing part of our lives being sick and in need of care.
#Does time spent in hospital in the final 15 years of life increase with age at death? A population based study, 1999
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC28281/
– Oxygen, radiation from the sun, our metabolism.
#Reactive oxygen species, nrf2 signaling, and human aging and diseases, 2018
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6229048/
#Ghrelin attenuates ultraviolet B radiation-induced impairment in capacities of epidermal stem cells, 2018
https://www.sciencedirect.com/science/article/abs/pii/S0753332217362261
(sun radiation)
#Molecular and biological hallmarks of ageing, 2016
https://onlinelibrary.wiley.com/doi/full/10.1002/bjs.10053
(radiation)
#Cellular Metabolism and Aging, 2018
https://www.sciencedirect.com/science/article/pii/S1877117317302077
– We all die because one of our important parts breaks.
#Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime, 2007
–Unnoticed by most of us, longevity research has made some unprecedented advances.
#Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime, 2007
#Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions, 2018
https://www.mdpi.com/1420-3049/23/2/509/htm
#The Search for Antiaging Interventions: From Elixirs to Fasting Regimens, 2014
– Think of the old greek myth of Tithonus for example.
#Tithonus, 2018
https://en.wikipedia.org/wiki/Tithonus
#Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime, 2007
– Thousands of years ago humans already feared never-ending old age.
#Studies in Comparative Mythology: Immortality as a Curse, 2017
http://www.carmentablog.com/2017/08/22/studies-comparative-mythology-immortality-curse/
#Apeirophobia: The Fear of Eternity, 2016
https://www.theatlantic.com/science/archive/2016/09/apeirophobia-the-fear-of-eternity/498368/
– The currently accepted maximum age of around 120.
#There’s no limit to longevity, says study that revives human lifespan debate, 2018
https://www.nature.com/articles/d41586-018-05582-3
#Breaking the Ceiling of Human Maximal Life span, 2018
https://academic.oup.com/biomedgerontology/article/73/11/1465/4602243
#Theoretical estimation of maximum human lifespan, 2009
https://link.springer.com/article/10.1007%2Fs10522-008-9156-4
– Nearly half of your lifetime healthcare costs will be spent during your senior years.
#The Lifetime Distribution of Health Care Costs, 2004
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361028/
#Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime, 2007
– And another third during middle age.
#The Lifetime Distribution of Health Care Costs, 2004
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361028/
– Most people assume that they will want to die once they reach a certain age.
#Here’s what people in their 90s really think about death, 2016
https://theconversation.com/heres-what-people-in-their-90s-really-think-about-death-58053
Further reading:
#Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime, 2007
– The challenges of living longer
#We DON'T want to live forever: Why a growing movement believe we shouldn't obsess over increasing life expectancy, 2012