Cores and Facilities

The goal of the SC INBRE Bioinformatics Core is to increase the National Institutes of Health research capacity of the state by providing bioinformatics support to faculty, post-doctoral fellows, graduate students, and undergraduate students of the lead and partner institutions. More

The mission of the IRF is to provide state-of-the-art biomedical research instrumentation for use in the USC SOM and USC main campus research environments. As time and resources permit, outside use of the facility is also permitted and encouraged. Technical assistance and training are available in most areas of research sponsored in the IRF. More

The Microarray Core Facility is a state-of-the-art facility that conducts gene expression profiling to monitor the levels of expression of all genes in the genome. Using our technology, a single experiment allows researchers to determine specific alterations in gene expression in various disease states, or progression, following exposure to drugs or chemicals. More

Provides genomics services, next generation sequencing for small scale genomes, targeted/amplicon resequencing and metagenomics. Bioinformatic service is provided for DNA microarray and next generation sequencing analysis. The facility also provides training in bioinformatic analysis, computational workstations for investigator use, and proprietary software licenses. Instrumentation available for investigator use. More

Claflin University Nuclear Magnetic Resonance (NMR) Facility

Claflin's NMR facility, in addition to its 700 MHz NMR, also has an automated nuclear magnetic resonance (NMR) sample changer to do NMR-based metabolomics research. The field of metabolomics focuses on changes to the small molecules that make up metabolism upon some stressful event or condition. NMR serves as an excellent detector of these small compounds; and statistical analysis is applied to many NMR sample replicates to increase the robustness of the metabolomics technique. Claflin University has the third highest field NMR laboratory in the state of South Carolina, just behind the Medical University of South Carolina (MUSC) and the Hollings Marine Laboratory (HML). Although a predominately undergraduate university and HBCU (Historically Black Colleges and Universities).

Dr. Muthukrishna Raja, Professor, Chemistry, Chemistry Molecular Science Research Center, Claflin University, (803) 535-5673, Email

Clemson University Genomics Institute (CUGI)

Also affiliated with SC INBRE is Clemson University Genomics Institute (CUGI): CUGI is a research/service engine tailored to design experiments built around functional hypotheses. CUGI has a breadth of experience in complex prokaryotic and eukaryotic genomics, transcriptomics, and bioinformatics and offers a comprehensive package of services from the extraction of nucleic acid to the collection of proper biological measurements with complex data analysis and interpretation through second-generation DNA/RNA sequencing and custom bioinformatics. Specifically, CUGI offers genomic library construction, transcriptome profiling (RNAseq) and statistical analysis, positional cloning and targeted sequencing, denovo genome sequencing and reference-based resequencing, GWAS experiments with complex variant analysis, methyl-seq, small RNA seq, genomic database construction, and custom bioinformatics. These tools are focused on the discovery and functional analysis of important genes, networks, and genomic regions from plants, animals, fungi, microbes, and humans and consist of extant and emerging technologies.

Dr. Christopher A. Saski, Director, CUGI, Research Faculty, Department of Genomics and Biochemistry, (864) 656-0973, Email

Visit the Clemson University Genomics Institute website