Systems Biotechnology and Cellular Engineering Lab

Welcome to the Systems Biotechnology and Cellular Engineering (SBCE) lab at the Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology - Madras. Our lab’s interdisciplinary research utilizes a combination of computational systems biology and machine learning tools, as well as molecular biology/cell biology/"-omics" based experimental techniques to deeply characterize the molecular processes of mammalian and microbial cells to develop innovative and industry-ready solutions for the manufacturing of biopharmaceuticals, cultivated meat and cell therapy products. We also develop computational tools to analyze large-scale multi-omics data and build mechanism based computational models, with a particular focus to enhance human health and well-being aspects. Our major research areas include systems biological analysis of cellular metabolism, protein homeostasis, transcriptional regulation, cell differentiation, immunometabolism and their interconnection with microbiomes. 

Please learn more about the various research areas of our lab here.