News

Parkinson's Group Celebrates one year of camaraderie

Members of the group include those with Parkinson’s disease, their caregivers, family members, and supporters. The meetings are typically the second Tuesday of the month and the support group holds the meetings in Spanish and English.

For their anniversary celebration the attendees were entertained by the musical group, Tremble Clefs, a therapeutic singing group for people living with Parkinson’s.

Blood Pressure Isradipine shows no benefit in Parkinson's Disease

PHILADELPHIA, May 3, 2019 /PRNewswire/ -- A study of a blood pressure drug does not show any benefit for people with Parkinson's disease, according to findings released today that will be presented at the American Academy of Neurology's 71st Annual Meeting in Philadelphia, May 4 to 10, 2019.

The drug isradipine had shown promise in small, early studies and hopes were high that this could be the first drug to slow the progression of the disease.

"Unfortunately, the people who were taking isradipine did not have any difference in their Parkinson's symptoms over the three years of the study compared to the people who took a placebo," said study author Tanya Simuni, MD, of Northwestern University Feinberg School of Medicine in Chicago and a member of the American Academy of Neurology.

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Infections Associated with Unapproved Stem Cell Injections

This health advisory informs providers about reports of serious infections after the use of stem cell injections that have not been approved by the U.S. Food and Drug Administration (FDA). Recommendations for local healthcare professionals and resource links are provided. More Information...

Posted April 2, 2019

Finding a biological marker ("biomarker") to identify people with Parkinson's disease before there are visible symptoms will speed development of new therapies and improve the quality of life for people living with Parkinson's. This article describes two easy-to-measure molecules that may turn out to be such useful biomarkers.

David Miles

Posted March 30, 2019

This actually works!

Constipation is a pain in the butt! (Sorry, I had to use the pun.) If you've tried natural remedies like prune juice or take over-the-counter or prescription drugs to no avail, try drinking hot water. Drink it in the morning and evening and a couple of times during the day. Do this over a series of days. Hopefully, you'll get results.

Maxine Baker

Domperidone, sold under the brand name Motilium™

A treatment for nausea and vomiting

"Domperidone, a dopamine antagonist that does not easily cross the blood-brain barrier, is considered the gold standard for treating gastrointestinal symptoms in patients with Parkinson's disease (PD) because the risk of developing extrapyramidal adverse effects* is considered minimal." Read More

*Extrapyramidal side effects: Physical symptoms, including tremor, slurred speech, akathesia, dystonia, anxiety, distress, paranoia, and bradyphrenia, that are primarily associated with improper dosing of or unusual reactions to neuroleptic (antipsychotic) medications.

Posted March 22, 2019

My husband has a very difficult time tying his shoes and slip-ons don’t fit his narrow feet well. These shoes have an ingenious system of velcro tabs along with regular laces. The tie-less system works very well, the soles are smooth enough that he doesn’t stumble on carpets, and the shoes are very comfortable. There are other types of shoes as well for those who don’t need the tie-less system but may want something for some other problems or just for comfort.

Martha Page

Two-part Documentary about GDNF Drug Trial in the UK.

Posted 12 March 2019

I mentioned in the support group a TV documentary about the GDNF drug trial taking place in Bristol, U.K. They had 42 participants and 50% are given a placebo. The trial was over a seven year period. Some people have posted the two episodes on YOU TUBE and can be searched via the title "The Parkinson's drug trial. A miracle cure?" It is also available at BBC.co.uk on the iPlayer that you have to sign up for. It is on channel 2 episode 1 played Feb 28, 9-10PM. Episode 2 played March 7, 9-10PM.

Best regards,

Karen

CBD: Still don't know much about it

Recommended by Maxine Baker, March 2019:

CBD comes up frequently in our Support Group discussions, and it's scheduled to be a speaker topic at one of our upcoming meetings. Some of us have tried CBD with varying degrees of success to treat a variety of symptoms. For those of us who haven't taken the plunge to try it yet, here's a recent article that appeared in The New York Times. I asked my movement disorder doctor whether I should try it to resolve a permanent toe cramp and she said: "It wouldn't hurt." I still haven't tried it, but at least the Times article helped set my expectations.

Falls: Minimizing the risk

Recommended by Maxine Baker, March 2019

We are of an age -- and our health is such -- that we are more prone to falling. Here's an article from The New York Times that offers some practical advice to remind us what we can do to minimize dangerous falls.

This article describes how stem cells are being used to grow clusters of different cell types found in the brain that are called "organioids" or "spheroids". These structures are proving to be remarkably good laboratory models that will further our understanding of neurological disorders like Multiple Sclerosis and Parkinson's Disease.