STEM - Milano, 17 Marzo 2026
Microbiome
Crash Course for Dummies
di Hubert Kubiak, Vittorio Ermoli, Pietro Natali, Vittorio Ravone
Crash Course for Dummies
di Hubert Kubiak, Vittorio Ermoli, Pietro Natali, Vittorio Ravone
The human microbiome is like an invisible world living alongside us everyday. It’s made up of trillions of tiny organisms such as bacteria, fungi, viruses, and many more that call our bodies home. Even though we can’t see them, they play a huge role in how we digest food, fight off illness, and even how we feel emotionally. Each person’s microbiome is completely unique, shaped by factors like genetics, lifestyle, and the foods we eat.
Bacteria are prokaryotic organisms (that are composed of only one cell) that can reproduce really fast and adapt to many environments. There are two kingdoms of bacteria: Eubacteria, which are the “true” bacteria, and the Archaebacteria, which are the oldest organisms on Earth and live in extreme conditions. They can be aerobic or anaerobic, depending on the surroundings and the presence of oxygen. In the human gut they are able to help the digestion of food, production of vitamins, and the protection against harmful pathogens.
Among the many microbes that support us, one standout is Bacteroides thetaiotaomicron. This helpful gut bacterium specializes in breaking down tough plant fibers we wouldn’t be able to digest on our own. In doing so, it creates short-chain fatty acids that help fuel our gut cells, calm inflammation, and support a healthy metabolism. It also adapts to whatever we eat, making it a steady partner in keeping our digestive system running smoothly.
Most microbiome research focuses on the gut, and for good reason. The microbes living there help produce vitamins, guide our immune system, and influence everything from our weight to our risk for certain diseases.
A balanced gut microbiome supports the immune system, helps control inflammation, and influences metabolism. On the other hand, when the diet isn’t well balanced we are vulnerable to harmful bacteria that can grow excessively. An example is Clostridioides difficile, a bacterium that can cause severe diarrhea and abdominal pain when the normal gut flora is reduced.
Maintaining a healthy microbiome through a balanced diet rich in fiber and fermented foods is essential for overall well-being. But the microbiome isn’t just in the gut, microbes on our skin help protect us from harmful germs and keep our skin barrier strong. Microbial communities in the mouth influence dental health, while others in the lungs and reproductive tract help keep those systems functioning properly.
Our daily choices, especially what we eat, play a big role in shaping these microbial communities. Diets rich in fiber, plants, and fermented foods help beneficial microbes thrive, while processed foods can reduce their diversity. The more we learn about this invisible ecosystem, the clearer it becomes that our health is closely tied to the microbes that live with us.