Clinical Proteomics Laboratory

Welcome to the HAN lab

Clinical Proteomics Laboratory (CPL), Seoul National University Hospital

서울대학교병원 임상 단백체학 실험실

"Innovating mass spectrometry to drive biological discovery and advance human health"

Our laboratory develops and applies advanced proteomics methods to study human health. We use mass spectrometric technology to answer fundamental questions in cell biology and to study human diseases including cancer, Alzheimer’s, diabetes, mental disorders, cancer, heart failure, obesity, asthma, among several others. The Proteomics Platform provides best-in-class mass spectrometry-based proteomic technologies and analysis capabilities to the Broad community and collaborators throughout the Korea and beyond, with the goal of addressing important questions in biology, chemistry, and clinical sciences through intensive collaboration. We continue to adopt and pioneer development of cutting-edge sample processing, data collection, and data analysis technologies of greatest importance.

  • Multi -omic and proteogenomic studies of a wide range of cancers, metabolic, mental disorders, neuro-, and infectious diseases
  • providing detailed views and understanding of cellular signaling networks related to protein phosphorylation, ubiquitylation, acetylation, and cross-talk
  • defining the targets of drugs or identifying protein interactors through chemical proteomics technologies and affinity purification (AP) mass spectrometry
  • studying degradation mechanisms of multi-protein complex and ribonucleoprotein (RNP) complex
  • developing biological understanding of response and resistance to therapy
  • inventing and optimizing proteomic technologies, automation methods, and computational analyses to increase speed, sensitivity, and completeness of proteome and post-translational modification data, and to improve the ability to extract new knowledge therefrom

Mass spectrometry

초고해상도 질량분석기 기반의 단백체 분석 facility

Biomarkers

정밀의료 예측 및 진단을 위한 초정밀 정량 기술

Bioinformatics

대용량 단백체 분석을 위한 생물정보학 기술

Mass spectrometry room in clinical proteomics laboratory

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