The Idea

PREDiSPOSED runs on combinatorial batching. Two times over, we take individual DNA samples, batch them, sequence them and then, bioinformatically, pin-point rare pathogenic mutations in individuals. This "trick" cuts costs up to 20-fold.

The Team

PREDiSPOSED has a multi-disciplinary team. Monogenic diseases exist in every medical specialty. With outset in oncogenetics, PREDiSPOSED involves experts from across medicine and anthropology, data science, epidemiology, etc.

The Plan

PREDiSPOSED finds rare, genetic disease. Despite the name, rare diseases are common; present in approx. 1 in 16 individuals. PREDiSPOSED explores whether earlier cost-effective diagnosis is, firstly, possible, secondly, meaningful for 100s of conditions.