My research:

Soon moving to I2SysBio Valencia, I currently work at the BioProcess Engineering Group (IIM-CSIC) developing tools for Biosystems Identification, Design and Control for Synthetic and Systems Biology applications. My main research interests are:

> Systematic inference of design principles of biological networks (through optimization).

> Automated design of genetic circuits for Synthetic Biology.

> Effective detection of complex behaviour in biochemical networks exploiting their inherent structural properties. I am particularly interested in the emergence of bistability and oscillations in gene regulation and cell signaling.

> The effect of molecular noise in gene regulation, and how to incorporate molecular noise in the design of biocircuits.

e-mail: twitter: @Otero_Muras

Participation in Recent/Upcoming Conferences:

  • Invited honorable speaker at the "Quantitative Modelling of Cell Metabolism Conference", Novo Nordisk Foundation, to be held in Copenhagen, Spring 2021

  • Keynote speaker at Gordon Conference "Biological Modeling, Directed Evolution and Complexity from Design to Application" (Waterville Valley, NH, USA) July 14-19, 2019

  • Plenary lecturer at the Advanced Lecture Course on Computational Systems Biology CompSysBio 2019 (March 31-April 6 Aussois, France)

  • Plenary speaker at the Bio-Inspired Analysis of Dynamical Systems International Workshop 2019 (January 10-12 Esztergom, Hungary)

Scientific Committees:

  • Program Commitee IWBDA 2020 International Workshop on Bio-Design Automation

  • Scientific Commitee CompSysBio 2021 Advanced Lecture Course on Computational Systems Biology

  • Member of the Technical Committee on BioProcesses and Biosystems of the International Federation of Automatic Control (IFAC).

  • National Organizing Committee of the 8th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE 2019).

Recent Publications:

You can find all my publications here:


After graduating in Chemical Engineering at Santiago de Compostela University I joined the Bioprocess Engineering Group at IIM-CSIC, where I developed my PhD thesis Modeling, dynamic analysis and control of biological networks defended on May 2010.

In 2010 I joined the Computational Systems Biology Group (Department of Biosystems Science and Engineering) at ETH-Zurich for a 3 year postdoc where i worked in the EU FP7 project IFNAction: A system view on the differential activities of human type I interferons.

Since 2013 I work at the BioProcess Engineering Group (IIM-CSIC), in the projects MULTISCALES: Multi-scale inference, monitoring, optimization and control: from cells to bioreactors, and SYNBIOFACTORY: Synthetic biology for bioproduction enhancement: Design, optimization, monitoring and control.

Editorial work:

from 2019 - Editorial Board Member of BMC Bioinformatics

from 2017- Editorial Board Member of BMC Systems Biology

from 2018- Editorial Board Member of Complexity


University of Vigo (2015)

M.Sc. in Biological Sciences> Systems Biology module (joint course).

ETH-Zürich (2010-2013)



  • Synthetic Biology (J. Stelling and S. Panke), Spring 2011

  • Synthetic Biology (J. Stelling and S. Panke), Spring 2010