期刊論文:
2025年-
Anti-inflammatory and anti-cancer effects of polysaccharides from Antrodia cinnamomea: A review. Zhi-Hu Lin, Sang-Nguyen-Cao Phan, Diem-Ngoc-Hong Tran, Mei-Kuang Lu, Tung-Yi Lin*. Journal of the Chinese Medical Association. 2025. 88:1-11.
F2-sulfated polysaccharides of Laetiporus sulphureus suppress triple-negative breast cancer cell proliferation and metastasis through the EGFR-mediated signaling pathway. Chia-I Jen, Lean-Teik Ng*. International Journal of Biological Macromolecule. 2025. 306(Pt 2):141407.
A highly sulfated α-1,4-linked galactoglucan of Antrodia cinnamomea with anti-Inflammatory and anti-cancer activities. Ching-Yi Lu, Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu*, Chia-Chuan Chang*. Carbohydrate Polymers. 2025.364, 123810.
2024年-
Sulfated polysaccharide from Antrodia cinnamomea mycelium cultured with zinc sulfate stimulates M1 polarization of macrophages through AKT/mTOR pathways. Zhi-Hu Lin, Hung-Chih Lo, Chia-Chuan Chang, Mei-Kuang Lu*, Ai-Jung Tseng, Chi-Hsein Chao, Chi-Hong Chao, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2024. 279:135548.
Targeting TGFβ receptor-mediated snail and twist: WSG, a polysaccharide from Ganoderma lucidum, and it-based dissolvable microneedle patch suppress melanoma cells. Hung-Chih Lo, Tzu-En Lin, Che-Yu Lin, Wei-Hao Wang, Yu-Chen Chen, Pei-Hsien Tsai, Jung-Chen Su, Mei-Kuang Lu, Wei-Hung Hsu, Tung-Yi Lin*. Carbohydrate Polymers. 2024. 341:122298.
Anti-inflammatory potential of low-molecular-weight and high-sulfation-degree sulfated polysaccharides extracted from Antrodia cinnamomea. Wei-Lun Qiu, Chi-Hsein Chao, Yu-Chi Hsu, Mei-Kuang Lu*. International Journal of Biological Macromolecules. 2024. 277(Pt 2):134360.
Anti-inflammatory and anti-lung cancer activities of low-molecular-weight and high-sulfate-content sulfated polysaccharides extracted from the edible fungus Poria cocos. Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu*. International Journal of Biological Macromolecules. 2024. 279(Pt 4):135483.
Sulfated polysaccharides of Laetiporus sulphureus fruiting bodies exhibit anti-breast cancer activity through cell cycle arrest, apoptosis induction, and inhibiting cell migration. Chia-I Jen, Mei-Kuang Lu, Ming-Nan Lai, Lean-Teik Ng*. Journal of Ethnopharmacology. 2024. 321:117546.
Sodium sulfate addition increases the bioresource of biologically active sulfated polysaccharides from Antrodia cinnamomea. Mei-Kuang Lu*, Meng-Hsin Lee, Chi-Hsein Chao, Yu-Chi Hsu. International Journal of Biological Macromolecules. 2024. 257(Pt 2):128699.
2023年前-
Advanced culture strategy shows varying bioactivities of sulfated polysaccharides of Poria cocos. Mei-Kuang Lu*, Chi-Hsein Chao, Yu-Chi Hsu. International Journal of Biological Macromolecules. 2023. 253(Pt 1):126669.
Significance of culture period on the physiochemistry and anti-cancer potentials of polysaccharides from mycelia of Ganoderma lucidum. Wei-Lun Qiu, Hung-Chih Lo, Mei-Kuang Lu*, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2023. 242(Pt 4):125181.
A branched 2-O sulfated 1,3-/1,4-galactoglucan from Antrodia cinnamomea exhibits moderate antiproliferative and anti-inflammatory activities. Mei-Kuang Lu, Chi-Hsein Chao, Tsu-Yuan Chang, Ming-Che Cheng, Yu-Chi Hsu, Chia-Chuan Chang*. International Journal of Biological Macromolecules. 2023. 241:124559.
ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death. Zhi-Hu Lin, Mei-Kuang Lu, Hung-Chih Lo, Chia-Chuan Chang, Ai-Jung Tseng, Chi-Hsein Chao, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2023. 238:124144.
Biochemical characterization and anti-cancer activity of tangential flow filtration system assisted purification of fucoglucan from Laminaria japonica. Tung-Yi Lin*, Hung-Chih Lo, Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu*, Hsien-Yeh Hsu*. International Journal of Biological Macromolecules. 2023. 227:1-9.
Develop a hybrid machine learning model for promoting microbe biomass production. Pu-Yun Kow, Mei-Kuang Lu, Meng-Hsin Lee, Wei-Bin Lu, Fi-John Chang*. Bioresource Technology. 2023. 369:128412.
SPS, a sulfated galactoglucan of Laetiporus sulphureus, exhibited anti-inflammatory activities. Mei-Kuang Lu*, Chia-I Jen, Chi-Hsein Chao, Yu-Chi Hsu, Lean-Teik Ng*. International Journal of Biological Macromolecules. 2023. 226:1236-1247.
A hybrid of response surface methodology and artificial neural network in optimization of culture conditions of mycelia growth of Antrodia cinnamomea. Meng-Hsin Lee, Wei-Bin Lu, Mei-Kuang Lu*, Fi-John Chang*. Biomass and Bioenergy. 2023. 158:106349.
Structural changes, and anti-inflammatory, anti-cancer potential of polysaccharides from multiple processing of Rehmannia glutinosa. Mei-Kuang Lu*, Chia-Chuan Chang, Chi-Hsein Chao, Yu-Chi Hsu. International Journal of Biological Macromolecules. 2022. 206:621-632.
Effect of carbohydrate-feeding strategy on the production, physiochemical changes, anti-inflammation activities of polysaccharides of Poria cocos. Mei-Kuang Lu*, Chi-Hsein Chao, Yu-Chi Hsu. International Journal of Biological Macromolecules. 2021. 192:435-443.
WSG, a glucose-enriched polysaccharide from Ganoderma lucidum, suppresses tongue cancer cells via inhibition of EGFR-mediated signaling and potentiates cisplatin-induced apoptosis. Wei-Hung Hsu, Wei-Jyun Hua, Wei-Lun Qiu, Ai-Jung Tseng, Hsin-Chung Cheng*, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2021. 193(Pt B):1201-1208.
WSG, a glucose-rich polysaccharide from Ganoderma lucidum, combined with cisplatin potentiates inhibition of lung cancer in vitro and in vivo. Wei-Lun Qiu, Wei-Hung Hsu, Shu-Ming Tsao, Ai-Jung Tseng, Zhi-Hu Lin, Wei-Jyun Hua, Hsin Yeh, Tzu-En Lin, Chien-Chang Chen, Li-Sheng Chen*, Tung-Yi Lin*. Polymers. 2021. 13(24):4353.
Structural sequencing and anti-inflammatory, anti-lung cancer activities of 1,4-α/β-sulfomalonoglucan in Antrodia cinnamomea. Mei-Kuang Lu, Chi-Hsein Chao, Yu-Chi Hsu, Chia-Chuan Chang*. International Journal of Biological Macromolecules. 2021. 170:307-316.
Arenarosides A-G, polyhydroxylated oleanane-type saponins from Polycarpaea arenaria and their cytotoxic and antiangiogenic activities. Nham-Linh Nguyen, Thanh-Hoa Vo, Yu-Chi Lin, Chia-Ching Liaw, Mei-Kuang Lu, Jing-Jy Cheng, Mei-Chuan Chen*, Yao-Haur Kuo*. Journal of Natural Products. 2021. 84(2):259-267.
Effects of WSG, a polysaccharide from Ganoderma lucidum, on suppressing cell growth and mobility of lung cancer. Wei-Hung Hsu, Wei-Lun Qiu, Shu-Ming Tsao, Ai-Jung Tseng, Mei-Kuang Lu, Wei-Jyun Hua, Hsin-Chung Cheng*, Hsien-Yeh Hsu*, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2020. 165(Pt A):1604-1613.
Effects of sterol-type elicitors on biochemical characterization of polysaccharides from Antrodia cinnamomea. Tung-Yi Lin*, Mei-Kuang Lu, Ai-Jung Tseng, Chi-Hsein Chao. International Journal of Biological Macromolecules. 2020. 162:1476-1483.
Production, characterization, and functions of sulfated polysaccharides from zinc sulfate enriched cultivation of Antrodia cinnamomea. Meng-Hsin Lee, Chi-Hsein Chao, Yu-Chi Hsu, Mei-Kuang Lu*. International Journal of Biological Macromolecules. 2020. 159:1013-1021.
Structural identification of a fucose-containing 1,3-β-mannoglucan from Poria cocos and its anti-lung cancer CL1-5 cells migration via inhibition of TGFβR-mediated signaling. Tung-Yi Lin, Mei-Kuang Lu, Chia-Chuan Chang*. International Journal of Biological Macromolecules. 2020. 157:311-318.
Fucoidan increased the sensitivity to gefitinib in lung cancer cells correlates with reduction of TGFβ-mediated Slug expression. Wei-Lun Qiu, Ai-Jung Tseng, Hsien-Yeh Hsu, Wei-Hung Hsu, Zhi-Hu Lin, Wei-Jyun Hua, Tung-Yi Lin*. International Journal of Biological Macromolecules. 2020. 153:796-805.
Physiochemical changes and mechanisms of anti-inflammation effect of sulfated polysaccharides from ammonium sulfate feeding of Antrodia cinnamomea. Mei-Kuang Lu*, Meng-Hsin Lee, Chi-Hsein Chao, Yu-Chi Hsu. International Journal of Biological Macromolecules. 2020. 148:715-721.