Eurotrip opens in the city of Hudson, Ohio, where Scott "Scotty" Thomas is dumped by his girlfriend, Fiona, immediately after his high school graduation. With his best friend, Cooper Harris, Scotty attends a graduation party that evening, where the band performs a song detailing the affair Fiona was having with the band's singer.
Scotty returns home drunk and angry and reads an email from his German pen pal, Mieke—who Scotty calls "Mike"—expressing sympathy for Scotty and suggesting they meet in person. Cooper suggests that "Mike" may be a sexual predator, and Scotty tells Mieke to stay away from him. Scotty's younger brother Bert informs him that "Mieke" is actually a common German feminine name. Realizing that he had mistaken her name, and that he has feelings for Mieke, Scotty tries to contact her again, but finds that Mieke has blocked his email address. Scotty decides to travel to Europe with Cooper to find Mieke and apologize in person.
Scotty and Cooper arrive in London, where they befriend a Manchester United football hooligan firm, led by Mad Maynard. After a night of drinking, Scotty and Cooper wake up on a bus on their way to Paris with the hooligans. In Paris, they meet up with their classmates Jenny and Jamie, fraternal twins who are touring Europe together. Jenny and Jamie decide to accompany Scotty and Cooper to find Mieke in Berlin. The group travels to Amsterdam, where Jamie is robbed while receiving oral sex in an alley, losing everyone's money, passports, and train tickets. They attempt to hitchhike to Berlin, but due to a language misunderstanding, they end up in Bratislava. Finding a great exchange rate with the U.S. dollar, the group goes to a nightclub. Drunk on absinthe, Jenny and Jamie make out with each other, witnessed by Scotty and Cooper, and are horrified when they realize what they are doing. The next day, a Slovak man drives them to Berlin, where they learn that Mieke has left with a summer tour group, and will be reachable in Rome for only a short time. Jamie sells his Leica Camera for plane tickets to Rome.
In Rome, the group heads to Vatican City, where Mieke is touring before her summer at sea. Inside the Vatican, Scotty and Cooper search for Mieke and accidentally ring the bell that signals the Pope has died. Scotty appears on a balcony and spots Mieke in the cheering crowd below, who have mistaken him for the newly elected pope. The Swiss Guards detains Scotty and Cooper for their actions, but they are rescued by the Manchester United hooligans from London. Scotty finally introduces himself to Mieke and confesses his love. Mieke is happy to see him, and they have sex in a confessional booth before she leaves on her trip. On the flight back to Ohio, Jenny and Cooper give into their urges and have sex in the plane's lavatory, while Jamie stays in Europe after being hired by Arthur Frommer.
Scotty moves to Oberlin College in the fall term. During a phone conversation with Cooper, who is now dating Jenny, Mieke knocks on his door, having been assigned to the same room because of another misunderstanding about her name. Scotty and Mieke embrace and get into bed together, with Cooper calling for Scott on the other end of a still-open cell phone call and the film closes with the Absinthe Green Fairy wondering at his own lack of a sex life.
Scott Mechlowicz as Scott "Scotty" Thomas:
Jacob Pitts as Cooper Harris:
Michelle Trachtenberg as Jenny:
Travis Wester as Jamie:
Jessica Boehrs as Mieke Schmidt:
innie Jones as Mad Maynard
Lucy Lawless as Madame Vandersexxx
Patrick Malahide as Arthur Frommer,
Diedrich Bader as Mugger,
Fred Armisen as Creepy Italian Guy,
Kristin Kreuk as Fiona
Nial Iskhakov as Bert Thomas
Matt Damon as Donny
J. P. Manoux as Robot Man
this is the extended version of Eurotrip