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For several years, we have noted the increased focus on addressing the perceived negative legacies in mining and sustainability or ESG drivers in general, which includes a drive to improve the post operational reputation of the mining sector. As an industry leader in addressing mining challenges, SLR has responded with an increasing project portfolio of international projects across our operating regions in Europe, Australia, Africa, and the Americas. In support of our international projects, UK based hydrologist Paul Klimczak, civil engineer Navika Erriah, and geochemists Jamie Robinson and Olivia Milton-Thompson have been working on an ongoing international pit lake closure mining project.

Resistant hypertension is highly prevalent among the general hypertensive population and the clinical management of this condition remains problematic. Different approaches, including a more intensified antihypertensive therapy, lifestyle modifications, or both, have largely failed to improve patients' outcomes and to reduce cardiovascular and renal risk. As renal sympathetic hyperactivity is a major driver of resistant hypertension, renal sympathetic ablation (renal denervation) has been recently proposed as a possible therapeutic alternative to treat this condition.