Our Research Group

清華大學-首頁故事報導 (https://www.nthu.edu.tw/hotNews/content/1195)

混合多種金屬元素的高熵合金奈米晶體已成為創新材料的明日之星，但科學家對不同元素的調配比例、如何均勻混合仍如瞎子摸象。本校化工系楊東翰副教授團隊創新研發出以「滴加法」來控制結晶體成長的技術，並建立全球第一個高熵合金奈米晶體資料庫，如同為成千上萬種組合的高熵材料訂出「雞尾酒指南」。有了它，將更能有效控制、預測並成功調配出新型高熵合金。自本校材料系特聘講座葉均蔚教授自2004年首度提出高熵合金理論以來，全球許多科學家前仆後繼地投入此一新領域研究。高熵即為「高亂度」，高熵合金混合了5種以上的金屬。但如何成功混合不同的金屬，且如「滴血認親」一樣使之相溶，就成了科學家的大挑戰。

楊東翰副教授表示，隨著研究發展的尺寸微縮技術，高熵材料也成功推進到了奈米尺度。高熵奈米晶體以其更大的表面積及更佳的催化性能，可提供幾乎「無限」的組合方式。但就因為它的元素組成複雜，如何調控它們互溶、不至於產生不均勻的分相結構；及如何調控晶體的表面排列，來提升催化的性能，成為團隊研究及挑戰的目標。楊東翰副教授團隊首先研究不同金屬前驅物的還原速率，讓有的快、有的慢的金屬前驅物還原速率趨於一致，找出讓它們同步互溶的關鍵因素，建立一套可調控且可預測的合成準則。團隊進一步研發出如同在珠核表面不斷包裹珍珠質形成養珠的方法，舉例來說，可以鈀為晶核，再滴加鐵、鈷、鎳、鉑、銠、釕、銥等金屬離子混合液到浸在還原劑中的晶核上，長出磊晶原子層。以這種方式造出的高熵合金奈米晶體，不但可以控制它的原子排列，如排成蜂巢或方陣，也可決定晶體堆疊成金字塔、立方體、或八面體等形狀。

楊東翰副教授指出，以滴加法發展出的磊晶成長技術，經過國家同步輻射研究中心的先進光源、臨場顯微分析，已證實金屬原子的確能均勻、一致地排列堆疊。以此方法造出的催化劑，應用於水解產氫，效率加倍，可望推進再生能源發展，為淨零排放作出貢獻。在突破結構控制的技術瓶頸、掌握高熵合金「定制法」後，楊東翰副教授團隊也成功建構出全球第一個可控制晶面的高熵奈米晶體資料庫，包含數十種新穎的奈米晶體，連續兩年登上了頂尖國際期刊《科學前沿》(Science Advances)。化工系林昆翰助理教授也對建構全球第一個高熵奈米晶體資料庫提供助力。由林昆翰助理教授領導的理論計算團隊運用電腦模擬來篩選最佳的金屬組成與晶面，並預測可能產生的材料特性，為進一步的實驗提供重要參考。林昆翰助理教授指出，雖然計算模型無法考慮所有實驗變因，但通過與實驗團隊的緊密合作，不斷調整和改良模型，已可產生與實驗十分相近的結果，期待未來能更進一步協助實驗團隊提高研究效率。

我們歡迎114學年度碩士生 (推甄生及考試生)、專題生及博士生加入我們的實驗室。

本實驗室致力於多元組成之晶體材料設計領域，研究晶體材料及其使用過程所涉及的化學原理與合成技術，目的在於探究原子級尺度內容，尋找晶體微結構與材料性能之關聯性。研究內容專注於金屬、多金屬、高熵合金、半導體、及異質晶體化學合成與定量技術解析晶體成核及成長機制。透過合適的晶體材料設計與控制，達到特定的物理、化學與光學性質，最終將所得之晶體材料應用於催化、氫能、與碳循環之領域。除了科學研究，我們亦發展一系列連續流動式化學反應器放大生產晶體材料，推動晶體材料實際應用於化工、汽車及半導體製程等工業。

我們致力於培養優秀的化工人才，將為研究生提供扎實的科學訓練與實作技能，學習範圍包括材料科學、奈米化學與技術、晶體鑑定與光譜分析、化學反應工程、反應器設計及觸媒工程。我們亦著重口語表達能力與簡報技巧訓練，鼓勵研究生與國外實驗室交流與研究，預期能對未來職涯發展有一大助益。我們亦歡迎大學部專題生加入我們團隊，專題生將執行獨立的研究主題，並有機會參與本實驗其他成員之研究，擁有獨立或共同發表國際期刊之機會。

歡迎對上述領域有興趣的大學部專題生、碩士生及博士生與我們聯繫，並歡迎您參觀我們實驗室，可讓您對本實驗室近況有更深入的了解。歡迎肯打拼、積極、對未來有高度期許的年輕人或預計未來攻讀國內外頂尖博士班者加入我們團隊。我們亦歡迎學術界及業界專家來訪指教，討論合作計畫，歡迎來信。

Representative publications:

• Jianlong He, Yueh-Chun Hsiao, Chia-Ying Wu, Younan Xia*, and Tung-Han Yang*. High-Entropy Alloy Nanocrystals: From Synthesis to Characterization and Catalytic Application. Chemical Reviews (2026, Accepted) (IF: 55.8) 

• Han-Wei Fang, Liang-Yu Hou, Chong-Chi Chi, Cheng-Yu Wu, Chia-Ying Wu, Chun-Wei Chang, Jui-Tai Lin, Shang-Cheng Lin, Zong Ying He, Yi Chen, Chia-Shuo Hsu, Chih-Wen Pao, Ming-Yen Lu, Kun-Han Lin, and Tung-Han Yang*. High-Index Faceted High-Entropy-Alloy Atomic Layers with Tailored Active Sites for Enhanced Catalytic Performance. Materials Today (2026, Accepted) (IF: 22.0) 

• I-Ting Kao, Rui-Tong Kuo, Shang-Cheng Lin, Yun-Shan Tsai, Lu-Yu Chueh, Chun‐Wei Chang, Kuan-Fang Lee, Liang-Ching Hsu, Jui-Tai Lin, Chia-Ying Wu, Chih-Wen Pao, Yung-Tin (Frank) Pan, Hong-Kang Tian*, and Tung-Han Yang*. Exploring a Bimetallic Catalyst Family for Hydrogen Oxidation with Insights into Superior Activity and Durability. Nature Communications (2025, Accepted) (IF: 15.7) (亦受國家同步輻射研究中心介紹)

• Yu-Mei Huang, Chun-Wei Chang, Jui-Tai Lin, Zong-Ying He, Yi Chen, Hsien-Shun Chang, Shang-Cheng Lin, Han-Yuan Liu, Yun-Shan Tsai, Shin-Chiao Lee, Kun-Han Lin, Chih-Wen Pao, Chung-Kai Chang, Yu-Chun Chuang, Ting-Shan Chan, and Tung-Han Yang*. Toward the Sabatier Principle-Guided Design of Low-Platinum-Group-Metal Trimetallic Nanocatalysts for Efficient Hydrogen Evolution and Oxidation Reactions. Advanced Functional Materials (2025, Accepted) (IF: 19.0) (亦受國家同步輻射研究中心介紹)

• Xin-Xuan Lin, Jui-Tai Lin, Ching-Yuan Tseng, Shang-Cheng Lin, Zong-Ying He, Yi Chen, Cheng-Kuang Lin, Kuan-Fang Lee, Chueh-Cheng Yang, Chia-Hsin Wang, Kun-Han Lin, and Tung-Han Yang*. Total Galvanic Replacement Strategy for Synthesizing Hollow Multimetallic Nanocrystals toward Enhanced Catalysis.  Advanced Functional Materials (2025, Accepted) (IF: 19.0) (亦受國家同步輻射研究中心介紹)

• Chih-Yi Lin, Zong Ying He, Jui-Tai Lin, Chun-Wei Chang, Yueh-Chun Hsiao, Shang-Cheng Lin,  Yi Chen,  Yu-Mei Huang, Shin-Chiao Lee, Chih-Wen Pao, Kun-Han Lin, Alexander J. Cowan, and Tung-Han Yang*. Atomically Mixed High-Entropy-Alloy Nanoframes with Three-Dimensional Subnanometer-Thick Electrocatalytic Surfaces. Advanced Functional Materials (2025, Accepted) (IF: 19.0) (亦受國家同步輻射研究中心介紹)

• Jui-Tai Lin, Yueh-Chun Hsiao, Chao Li, Ching-Yuan Tseng, Zong-Ying He, Adrian M. Gardner, Yi Chen, Chueh-Cheng Yang, Chia-Hsin Wang, Shang-Cheng Lin, Xin-Xuan Lin, Chih-Yi Lin, Kun-Han Lin, Alexander J. Cowan*, and Tung-Han Yang*. Spectroscopic and Theoretical Insights into High-Entropy-Alloy Surfaces and Their Interfaces with Semiconductors for Enhanced Photocatalytic Hydrogen Production. Small (2025, Accepted) (IF: 13.0) 

• Yueh-Chun Hsiao, Cheng-Yu Wu, Chih-Heng Lee, Wen-Yang Huang, Ho Viet Thang, Chong-Chi Chi, Wen-Jing Zeng, Jia-Qi Gao, Chih-Yi Lin, Jui-Tai Lin, Adrian M. Gardner, Hansaem Jang, Ruai-Hung Juang, Yi-Hong Liu, Islam M. A. Mekhemer, Ming-Yen Lu, Ying-Rui Lu, Ho-Hsiu Chou, Chun-Hong Kuo, Shan Zhou, Liang-Ching Hsu*, Hsin-Yi Tiffany Chen*, Alexander J. Cowan*, Sung-Fu Hung*, Jien-Wei Yeh*, Tung-Han Yang*. A Library of Seed@High-Entropy-Alloy Core-Shell Nanocrystals with Controlled Facets for Catalysis. Advanced Materials (2025, Accepted) (IF: 27.4) (亦受清大校務年報報導)

• Ting-Hsin Hu, Cheng-Yu Wu, Zong Ying He, Yi Chen, Liang-Ching Hsu, Chih-Wen Pao, Jui-Tai Lin, Chun-Wei Chang, Shang-Cheng Lin, Rachel Osmundsen, Lee Casalena, Kun Han Lin, Shan Zhou,  Tung-Han Yang*. Unconventional Hexagonal Close-Packed High-Entropy Alloy Surfaces Synergistically Accelerate Alkaline Hydrogen Evolution. Advanced Science (2025, Accepted) (IF: 14.3) (亦受國家同步輻射研究中心Activity Report介紹:  When Order Defies Nature: Hexagonal High-Entropy Nanocrystals for Accelerated Hydrogen Evolution by 台大化工康敦彥教授)

• Cheng-Yu Wu, Yueh-Chun Hsiao, Yi Chen, Kun-Han Lin, Tsung-Ju Lee, Chong-Chi Chi, Jui-Tai Lin, Liang-Ching Hsu, Hsin-Jung Tsai, Jia-Qi Gao, Chun-Wei Chang, I-Ting Kao, Chia-Ying Wu, Ying- Rui Lu, Chih-Wen Pao, Sung-Fu Hung, Ming-Yen Lu, Shan Zhou, Tung-Han Yang*. "A Catalyst Family of Metastable High-Entropy-Alloy Atomic Layers with Square Atomic Arrangements Comprising Iron- and Platinum-Group Metals " Science Advances (2024, Accepted) (IF: 11.7) (亦受清大首頁故事: 清華大學建立全球第一個高熵合金奈米晶體資料庫及數個科學媒體報導) 

• Shang-Cheng Lin, Chun-Wei Chang, Meng-Hsuan Tsai, Chih-Hao Chen, Jui-Tai Lin, Chia-Ying Wu, I-Ting Kao, Wen-Yang Jao, Chia-Hsin Wang, Wen-Yueh Yu, Chi-Chang Hu, Kun-Han Lin* and Tung-Han Yang*. Decreasing the O2-to-H2O2 Kinetic Energy Barrier on Dilute Binary Alloy Surfaces with Controlled Configurations of Isolated Active Atoms. Advanced Functional Materials (2024, Accepted) (IF: 19.0)

• Yi-Hong Liu, Chia-Jui Hsieh, Liang-Ching Hsu, Kun-Han Lin, Yueh-Chun Hsiao, Chong-Chi Chi, Jui-Tai Lin, Chun‐Wei Chang, Shang-Cheng Lin, Cheng-Yu Wu, Jia-Qi Gao, Chih-Wen Pao, Yin-Mei Chang, Ming-Yen Lu, Shan Zhou, and Tung-Han Yang*. Toward controllable and predictable synthesis of high-entropy alloy nanocrystals. Science Advances 2023, 9, eadf9931. (IF: 11.7) (亦受國家同步輻射研究中心、國科會化學圖書電子報、材料牛等科學媒體報導) (台灣觸媒學會傑出研究論文獎)

• Jui-Tai Lin, Yi-Hong Liu, Chi-Yen Tsao, Cheng-Yu Wu, Chia-Jui Hsieh, Meng-Zhe Chen, Chun‐Wei Chang, Yueh-Chun Hsiao, Hsin-Lung Chen, and Tung-Han Yang*. Toward a Quantitative Understanding of Crystal-Phase Engineering of Ru Nanocrystals. Chemistry of Materials  (2023, In press) (IF: 10.5)

• Kei Kwan Li, Chia-Ying Wu, Tung-Han Yang, Dong Qin, and Younan Xia*. Quantification, Exchange, and Removal of Surface Ligands on Noble-Metal Nanocrystals. Accounts of Chemical Research (2023, in press) (N/M (Chemistry, Multidisciplinary): 7/179 = 4%; IF: 24.4)

• T. H. Yang, J. Ahn, S. Shi, and D. Qin*. Understanding the Role of Poly(vinylpyrrolidone) in Stabilizing and Capping Colloidal Silver Nanocrystals. ACS Nano 2021, 15, 14242. (N/M (Chemistry, Multidisciplinary): 13/172 = 7%; IF: 18.0)

• T. H. Yang, J. Ahn, S. Shi, P. Wang, R. Gao, and D. Qin*. Noble-Metal Nanoframes and Their Catalytic Applications. Chemical Reviews 2021, 121, 796. (Chemistry, Multidisciplinary): 1/172 = 1%; IF: 60.6)

• T. H. Yang+, Y. Shi+, A. Janssen+, and Y. Xia*. Surface Capping Agents and Their Roles in Shape-Controlled Synthesis of Colloidal Metal Nanocrystals. Angewandte Chemie International Edition 2020, 59, 2. (+Equal Contribution) (N/M (Multidisciplinary Sciences): 16/172 = 9%; IF: 12.3)

• T. H. Yang and D. Qin*. Capturing the Equilibration Pathway of Nanomaterials Metastable in Both Crystal Structure and Morphology. Matter 2020, 2, 519. (Invited Preview) (IF: 15.5)

• S. Zhou, M. Zhao, T. H. Yang, and Y. Xia*, Decahedral Nanocrystals of Noble Metals: Synthesis, Characterization, and Applications. Materials Today 2019, 22, 108. (N/M (Materials Science, Multidisciplinary): 5/284 = 2%; IF: 31.0)

• T. H. Yang+, K. C. Chiu+, Y. W. Harn, H. Y. Chen, R. Cai, S. C. Lo, J. M. Wu, and Y. H. Lee*. Electron Field Emission of Geometrically-Modulated Monolayer Semiconductors. Advanced Functional Materials 2018, 28, 1706113. (+Equal Contribution) (Highlighted as Back Cover). (N/M (Materials Science, Multidisciplinary): 10/284 = 3%; IF: 18.8)

• S. Zhou, D. Huo, T. H. Yang, Z. Lyu, M. Zhao, K. Gilroy, Y. Wu, Z. D. Hood, M. Xie, and Y. Xia*. Enabling Complete Ligand Exchange on the Surface of Gold Nanocrystals through the Deposition and then Etching of Silver. Journal of the American Chemical Society 2018, 141, 11898. (N/M (Chemistry, Multidisciplinary): 8/172 = 5%; IF: 15.4)

• T. H. Yang, S. Zhou, K. D. Gilroy, L. Figueroa-Cosme, Y. H. Lee, J. M. Wu, and Y. Xia*. Autocatalytic Surface Reduction and Its Role in Controlling Seed-Mediated Growth of Colloidal Metal Nanocrystals. PNAS 2017, 114, 13619. (Highlighted in Georgia Tech News: Project Will Provide Reaction Kinetics Data for Deterministic Synthesis of Metallic Nanocrystals, NSF, and Many Other News Media). (N/M (Multidisciplinary Sciences): 5/64 = 8%; IF: 11.2)

• T. H. Yang, H. C. Peng, S. Zhou, C. T. Lee, S. Bao, Y. H. Lee, J. M. Wu, and Y. Xia*. Toward a Quantitative Understanding of the Reduction Pathways of a Salt Precursor in the Synthesis of Metal Nanocrystals. Nano Letters 2017, 17, 334. (N/M (Materials Science, Multidisciplinary): 19/284 = 7%; IF: 12.3)

• K. D. Gilroy+, A. O. Elnabawy+, T. H. Yang+, L. T. Roling, J. Howe, M. Mavrikakis*, and Y. Xia*. Thermal stability of Metal Nanocrystals: An Investigation of the Surface and Bulk Reconstructions of Pd Concave Icosahedra. Nano Letters 2017, 17, 3655. (+Equal Contribution) (N/M (Materials Science, Multidisciplinary): 19/284 = 7%; IF: 12.3)

• T. H. Yang, K. D. Gilroy, and Y. Xia*. Reduction Rate as a Quantitative Knob for Achieving Deterministic Synthesis of Colloidal Metal Nanocrystals. Chemical Science 2017, 8, 6730. (Chemistry, Multidisciplinary): 17/172 = 10%; IF: 9.8)

• T. H. Yang, Y. W. Harn, M. Y. Pan, L. D. Huang, M. C. Chen, B. Y. Li, P. H. Liu, P. Y. Chen, C. C. Lin, P. K. Wei, L. J. Chen, and J. M. Wu*. Ultrahigh Density Plasmonic Hot Spots with Ultrahigh Electromagnetic Field for Improved Photocatalytic Activities. Applied Catalysis B: Environmental 2016, 181, 612. (N/M (Engineering, Chemical): 3/137 = 2%; IF: 19.5)

• T. H. Yang+, L. D. Huang+, Y. W. Harn, C. C. Lin, J. K. Chang, C. I. Wu, and J. M. Wu*. High Density Unaggregated Au Nanoparticles on ZnO Nanorod Arrays Function as Efficient Photocatalysts for Environmental Purification. Small 2013, 9, 3169. (+Equal Contribution) (N/M (Physics, Applied): 10/146 = 7%; IF: 13.8)

• T. H. Yang and J. M. Wu*. Thermal Stability of Sol-Gel P-Type Al-N Codoped ZnO Films and Electric Properties of Nanostructured ZnO Homojunctions Fabricated by Spin-Coating Them on ZnO Nanorods. Acta Materialia 2012, 60, 3310. (N/M (Metallurgy & Metallurgical Engineering): 1/75 = 1%; IF: 8.2)

Sponors and partners: