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4) As part of the entry, contestants will enter a guess as to the actual number of candy hearts in the jar pictured on the entry page. The photo is of an actual jar filled with candy hearts that have been counted and recorded by Big Radio contest management.

5) On February 13th, WCLO will declare the contestant guessing closest to the actual number of hearts, either over or under, the winner. In the event of a tie, a random drawing will be held of the tying contestants to determine a winner. The winner will be notified via email and/or telephone and be announced on WCLO at 9:10am on Monday, 2/13/2023. The grand prize package includes:

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Background:  Patients with open chest wounds, either related to trauma or cardiothoracic procedures, are subjected to significant physiologic alterations when undergoing chest wound closure. Sudden increased intrathoracic pressure at closure decreases venous return from the brain to the heart; consequently the total blood volume in the ridged skull increases, resulting in increased intracranial pressure (ICP). Patients with intact cerebrovascular autoregulation can compensate for these sudden changes by adjusting cerebral blood flow to maintain physiologic ICP. In cases where the autoregulatory mechanisms are compromised, such as stroke or trauma, the ICP can become pathologically elevated. If the patient does not have an ICP monitor, the spike in ICP can go unrecognized, compromising cerebral perfusion pressure and resulting in increased morbidity and mortality.

Case description:  Herein we describe a case of pathologic elevations in ICP captured with an ICP monitor at the time of chest wound closure in a patient with delayed chest wound closure after orthotopic heart transplant and comorbid embolic stroke.

We present an imaging and image reconstruction pipeline that captures the dynamic three-dimensional beating motion of the live embryonic zebrafish heart at subcellular resolution. Live, intact zebrafish embryos were imaged using 2-photon light sheet microscopy, which offers deep and fast imaging at 70 frames per second, and the individual optical sections were assembled into a full 4D reconstruction of the beating heart using an optimized retrospective image registration algorithm. This imaging and reconstruction platform permitted us to visualize protein expression patterns at endogenous concentrations in zebrafish gene trap lines.

Steve M Antoine, Robert Percy, Srinivasan Sattiraju, Fatal paradoxical emboli captured in transit through a patent foramen ovale, European Heart Journal - Case Reports, Volume 2, Issue 4, December 2018, yty114, e24fc04721

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