Tubulin is highly conserved across Apicomplexa, however, the number and structural arrangement of microtubules formed by polymerization of a tubulin heterodimers is very different among Apicomplexan parasites. Microtubules in this group of parasites have been suggested to be involved in cellular integrity, cell division and invasion. The structural arrangement and functional activity of microtubules has been studied in the laboratory with two prominent Apicomplexans, Plasmodium falciparum and Babesia bovis. Different stages of the Apicomplexans' life cycle were studied under normal conditions and in altered states using anti-mitotic compounds with the aim to learn more about the role played by microtubules in the biology of these parasites and to use this knowledge in developing strategic interventions in form of novel drugs.