Minah Suh Lab

Our laboratory aims to understand the physiological and pathological interactions among neurons, glial cells, immune cells, and the vascular system using multimodal imaging and functional approaches.

• Alzheimer’s disease and neurodegeneration

Investigate the cellular and molecular mechanisms underlying Alzheimer’s disease and other neurodegenerative disorders, with a particular focus on neuron–glia interactions, neuroinflammation, abnormal neuronal activity, and vascular dysfunction.

• Brain tumor microenvironment

Investigate interactions among tumor cells, neurons, glial cells, immune cells, and the vascular system in the brain tumor microenvironment, and examine how these interactions contribute to tumor progression and functional changes in the brain.

• Neuron–glia and neuroimmune interactions

Study how microglia, astrocytes, and immune signaling regulate neuronal function and disease pathology, and explore their potential as therapeutic targets for neurological disorders.

• Neurovascular coupling in health and disease

Investigate the cellular and molecular mechanisms of neurovascular coupling and examine how pathological neuronal excitation and synchronization alter cerebral hemodynamics, vascular responses, and brain function at both functional and structural levels.

• Multimodal imaging of brain function and pathology

Develop and apply multimodal imaging approaches to characterize neuronal activity, glial responses, vascular dynamics, and structural changes across multiple spatial and temporal scales.