1. Regulation of Stem Cell Functions Including Migration and Differentiation
Regulation of neuronal and osteogenic differentiation of MSCs by functionalized materials including graphene substrate
Inhibition of adipogenesis of stem cells by natural products including flavonols and peptides
Characterization of chemokines and the chemokine receptors involved in stem cell differentiation
Regulation of the migration and interaction of immune cells to stem cells
2. Novel Peptide Drugs
In silico identification of novel peptides by using Omics and AI techniques
Development of therapeutic peptides for anti-micorbial, anti-inflammatory, and wound healing functionalities
3. Organoids and Organ-on-a-chip to Evaluate Toxicity of Hazardous Substances and Drugs
Development of biomarkers for diagnosis for human exposed to hazardous chemicals and toxic drugs
Elucidating toxicity mechanisms using organoids and developing biomimetic chips based on these mechanisms
Biological mechanisms to attenuate genotoxicity and cytotoxicity induced by dietary benzopyrene
4. Nanomaterials for Biomedical and Environmental Applications
Biological functionalization of nanoparticles for antitumor and antimicrobial activities
Biological evaluation of nanotoxicity using 3D cell culture system
Development of nano-materials utilizing water waste and soil minerals
5. Maintenance of Genome Stability and DNA Damage Repair
Identification and biological characterization of antioxidant compounds
DNA damage signaling associated with early apoptosis
Regulation of base excision DNA repair pathways during stem cell differentiation
Benzo[a]pyrene 유도 MASLD(대사관련 지방간질환) 기전 규명 및 치료 효능 물질 발굴