Publications

Highlights

• Bioadhesives: Science [12], Science [36], Adv. Mater. [25], Adv. Func. Mater. [58]

• Hydrogels: Nature Rev. Mater. [10], Adv. Func. Mater. [44], Science Advances [21]

• Mechanics of Soft Materials: PNAS [47], Mech. Mater. [27], ACS Macro Lett. [24]

• Tissue Engineering: Science Advances [16], Mater. Horizons [38], Adv. Sci. [32], Mater. Horizons [19]

• Blood Clot Engineering: Nature Communications [37], Acta Biomaterialia [54], J. Mech. Phys. Solids [62]

Papers

† Equal contribution; * Corresponding author; ^ my students; IF impact factor. 

The pdf files of papers are available for fair use. Also, see Google Scholar (Collective citations >8000). 

(66) Swen Groen, et al. TBD (2024). 

(65) Xiaoyi Lan^, Evan Johnston^, Tianqin Ning^, Guojun Chen, Lisbet Haglund*, Jianyu Li*, TBD (2024). 

(64) Yixun Cheng^, et al., Jianyu Li*, TBD (2024). 

(63) Alexander Nottegar^, Shuaibing Jiang^, Zhen Yang^, Ting Wang^, Amirali Shahi, Huiqi Shi, Malvika Nagrath^, Xuan Li^, Ran Huo^, Zu-hua Gao, Rong Long, Gilles Soulez, Sophie Lerouge, and Jianyu Li*, TBD (2024). 

(62) Shiyu Liu^, Aram Bhamani^, Gabriella Paige Sugerman, Zhen Yang^, Manuel Rausch, Farshid Ghezelbash*, and Jianyu Li*, Adhesive and cohesive fracture of blood clots: Experiments and modeling, Journal of the Mechanics and Physics of Solids, 105858 (2024). 

(61) Shuaibing Jiang^, Tony Jin, Tianqin Ning^, Zhen Yang^, Zhenwei Ma^, Ran Huo^, Yixun Cheng^, Davis Kurdyla, Edmond Lam, Rong Long, Audrey Moores*, and Jianyu Li*, Nanowhisker glues for fatigue-resistant bioadhesion and interfacial functionalization, Nature Communications, Under Revision (2024). 

(60) Xiaona Cao, Tianxu Fang, Mo Chen, Tianqin Ning^, Jianyu Li, Peter Siegel, Morag Park, Zhitong Chen, Guojun Chen, Trehalose enhanced cold atmospheric plasma-mediated cancer treatment, Biomaterials, 122582 (2024). 

(59) Xuan Li^, Ran Huo^, Li Li, Hosni Cherif, Lisbet Haglund*, Jianyu Li*, Composite hydrogel sealants for annulus fibrosus repair, ACS Biomaterials Science and Engineering, 10 (8), 5094-5107 (2024). 

(58) Zhenwei Ma^†, Ran Huo^†, Alexander Nottegar^, Christopher Chung‐Tze‐Cheong^, Qiman Gao, Xiaoyi Lan^, Zu-hua Gao, Jianyu Li*, Bioinspired printable tough adhesives with in situ benignly triggered mechanical enhancements, Advanced Functional Materials, 2403290 (2024). 

(57) Aram Bahmani^†, Shiyu Liu^†, Evan Johnston^, Weiyi Wan^, Alex Nottegar^, Ran Huo^, Shuaibing Jiang^, Jianyu Li*, Engineering highly cellularized living materials with agitation, TBD (2024). 

(56) Alex Ross, Xixi Guo, German A. Mercado Salazar, Sergio David Garcia Schejtman,
Jinane El-Hage, Maxime Comtois-Bona, Aidan Macadam, Irene Guzman-Soto,
Hiroki Takaya, Kevin Hu, Bryan Liu, Ryan Tu, Bilal Siddiqi, Erica Anderson,
Marcelo Muñoz, Patricio Briones-Rebolledo, Tianqin Ning^, May Griffith, Benjamin Rotsein, Horacio Poblete, Jianyu Li, Marc Ruel,* Erik J. Suuronen,* and Emilio I. Alarcon*, Multipurpose on the spot gelling peptide-based engineered materials for skin, cornea, and heart repair, Advanced Functional Materials, 2402564 (2024).

(55) Baoling Huang^, Stephanie Makhlouf^, Xuan Li^, Alex Nottegar^, Shuaibing Jiang^, Ting Wang^, Aram Bahmani^, Jianyu Li*, TBD (2024). 

(54) Shiyu Li^†, Aram Bahmani^†, Farshid Ghazhebash^, Jianyu Li*, Fibrin clot fracture under cyclic fatigue and variable rate loading, Acta Biomaterialia, 177, 265-277 (2024). 

(53) H. Cherif, Li Li, J Snuggs, Xuan Li^, C Sammon, Jianyu Li, L Beckman, Lisbet Haglund, C.L. Le Maitre, Injectable hydrogel induces regeneration of naturally degenerate human intervertebral discs in a loaded organ culture model, Acta Biomaterialia, 176, 201-220 (2024). 

(52) Nicolas Juncos Ljubich, Justin Puma^, Zi Xin Zhang, Jianyu Li, Changhong Cao, Development of a Bio-Hybrid Mosquito Stinger-Based Atomic Force Microscopy Probe, Journal of Visualized Experiments, 206 (2024).

(51) Yin Liu^, Li Li, Xuan Li^, Hosni Cherif, Michael H. Weber, David Juncker, Nicole Y. K. Li-Jessen, Lisbet Haglund*, Jianyu Li*. Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration, Acta Biomaterialia, 180, 244-261 (2024). 

(50) Xuan Li^, Yin Liu^, Shiyu Liu^, Baolin Huang^, Nicole Li-Jessen, Lisbet Haglund, Jianyu Li*. Designing Regenerative Bioadhesives for Tissue Repair and Regeneration, Advanced Therapeutics, 7 (1), 2300139 (2024). Invited paper. IF 5.0.

(49) Shuaibing Jiang^, Guangyu Bao^, Zhen Yang^, Aram Bahmani^, Xingwei Yang, Alex Nottegar^, Jun Kim, Ran Huo^, Xuan Li^, Anastasia Nijik, Zu-hua Gao, Rong Long, Christian Kastrup, and Jianyu Li*. TBD (2023). 

(48) David Mazy^, Christopher Chung-Tze-Cheong^, Zhenwei Ma^, Ran Huo^, Stephanie Lamer, Jianyu Li*, Marie-Lyne Nault*, Tough Gel Adhesive is an Effective Method for Meniscal Repair in a Bovine Cadaveric Study, Journal of Experimental Orthopaedics, 10, 1, 1-10 (2023).

(47) Zhen Yang^, Guangyu Bao†^, Ran Huo†^, Shuaibing Jiang^, Xingwei Yang, Xiang Ni^, Luc Mongeau, Rong Long, Jianyu Li*, Programming hydrogel adhesion with engineered polymer network topology, Proceedings of the National Academy of Sciences of USA, 120, 39 (2023). Supporting Information. IF 12

(46) Zhenwei Ma^, Alex Nguyen^, Christopher Chung-Tze-Cheong^, David Mazy^, Farshid Ghezelbash^, Zhen Yang^, Yin Liu^, Shiyu Liu^, Stephanie Lamer, Zu-hua Gao, Favour Obuseh, Benjamin R. Freedman, Marie-Lyne Nault, Jianyu Li*, Tough adhesive puncture sealing sutures with swelling triggered bioadhesion for enhanced wound closure. Advanced Materials Technology, 2301594 (2024). IF 6.8

(45) David Mazy^, Zhenwei Ma^, Christopher Chung-Tze-Cheong^, Stephanie Lamer, Jianyu Li, Marie-Lyne Nault, Modification of the properties of a suture thread with a tough gel coating: A baseline ex-vivo study. Journal of Orthopaedic Research, 41, 8, 1815 (2023). IF 3.0

(44) Ran Huo^, Guangyu Bao^, Zhenwei Ma^, Zixin He, Roozbeh Moakhar, Zhen Yang^, Shuaibing Jiang^, Xuan Li^, Christopher Chung^, Alexander Nottegar^, Changhong Cao, Sara Mahshid, Jianyu Li*, Tough transient ionic junctions printed with ionic microgels, Advanced Functional Materials, 2213677 (2023). IF 20. 

• selected as a front cover of the journal. 

(43) Jing Liu, Zhizhi Sheng, Mengchuang Zhang, Jianyu Li, Yunmao Zhang, Xue Xu, Shijie Yu,  Min Cao, and Xu Hou, Non-Newtonian fluid gating membranes with acoustically responsive and self-protective gas transport control, Materials Horizons, 10, 899-907 (2023). IF 15.7.

(42) Ruiqi Yang^, Guangyu Bao^, Huizhu Li, Hong Liu, Jun Chen*, Jianyu Li*, Dongling Ma*, Lead/cadmium-free near-infrared multifunctional nanoplatform for deep-tissue bimodal imaging and drug delivery, Materials Today Advances, 16, 100306 (2022). Invited paper. IF 10.25

(41) Keegan Mendez, William Whyte, Benjamin R. Freedman, Sandra E. Rothenbucher, Yiling Fan, Manisha Singh, Jianyu Li, David J. Mooney, Ellen T. Roche, Mechanoresponsive drug release from a flexible, tissue-adherent, hybrid hydrogel actuator, Advanced Materials, 2303301 (2022). IF 29

(40) Christian Rafael Moya-Garcia, Hideaki Okuyama, Nader Sadeghi, Jianyu Li, Maryam Tabrizian and Nicole Y. K. Li-Jessen*, In vitro models for head and neck cancer: Current status and future perspective, Frontiers in Oncology, 3691 (2022). 

(39) Shuaibing Jiang^, Shiyu Liu^, Sum Lau^, Jianyu Li*, Hemostatic biomaterials to halt non-compressible hemorrhage, Journal of Materials Chemistry B, 10, 7239-7259 (2022). IF 7

(38) Xuan Li^, Yin Liu^, Li Li, Ran Huo^, Farshid Ghezelbash^, Zhenwei Ma^, Guangyu Bao^, Shiyu Liu^, Zhen Yang^, Michael H. Weber, Nicole Y. K. Li-Jessen, Lisbet Haglund*, Jianyu Li*. Tissue-mimetic hybrid bioadhesives for intervertebral disc repair. Materials Horizons, 10 (5), 1705-1718 (2023). IF 15.7.

• Featured in the regional spotlight collection of Materials Horizons. 

(37) Guangyu Bao^, Qiman Gao, Massimo Cau, Nabil Ali-Mohamad, Mitchell Strong, Shuaibing Jiang^, Zhen Yang^, Amin Valiei, Zhenwei Ma^, Marco Amabili, Zu-Hua Gao, Luc Mongeau, Christian Kastrup, Jianyu Li*, Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage, Nature Communications, 13, 5035 (2022). Supporting Information. IF 17.7

• Coverages: ASME, McGill Tribune, McGill Newsroom 
• Bioeng pick of the week by Nature Reviews Bioengineering 

(36) Zhenwei Ma^, Claire Bourquard, Qiman Gao, Shuaibing Jiang^, Tristan De Iure-Grimmel^, Ran Huo^, Xuan Li^, Zixin He, Zhen Yang^, Galen Yang, Yixiang Wang, Edmond Lam, Zu-Hua Gao, Outi Supponen*, Jianyu Li*, Controlled tough bioadhesion mediated by ultrasound, Science, 377, 751-755 (2022). Supporting Information. IF 63

• Coverages: Science Magazine, McGill Newsroom, Physicsworld.com

(35) Farshid Ghezelbash^, Shiyu Liu^, Aboulfazl Shirazi-Adl, Jianyu Li*, Blood clot behaves as a poroviscoelastic material, Journal of the Mechanical Behavior of Biomedical Materials, 128, 105101 (2022). 

(34) Mika Brown, Jianyu Li, Christopher Moraes, Maryam Tabrizian, Nicole Li-Jessen, Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine, Biomaterials, 121786 (2022). 

(33) Patrick Coburn, Xuan Li^, Jianyu Li, Yo Kishimoto, Nicole Li-Jessen, Progress in vocal fold regenerative biomaterials: An immunological perspective, Advanced NanoBiomed Research, 2100119 (2021).

(32) Sareh Taheri†, Guangyu Bao^†*, Zixin He, Sepideh Mohammadi, Hossein Ravanbakhsh, Larry Lessard, Jianyu Li*, Luc Mongeau*, Injectable, pore-forming, perfusable double-network hydrogels resilient to extreme biomechanical stimulations, Advanced Science, 2102627 (2021). 

• 2021 Top Downloaded Article in Advanced Science. 

(31) Tony Jin, Tracy Liu, Shuaibing Jiang^, Davis Kurdyla, Vladimir Michaelis, Brittney Klein, Edmond Lam*, Jianyu Li*, Audrey Moores*, Chitosan nanocrystals synthesis via aging and application towards alginate hydrogels for sustainable drug release, Green Chemistry, 23, 6527-6537 (2021). 

(30) Guangyu Bao^, Ran Huo^, Zhenwei Ma^, Mitchell Strong, Amin Valiei, Shuaibing Jiang^, Shiyu Liu^, Luc Mongeau, Jianyu Li*, Ionotronic tough adhesives with intrinsic multifunctionality, ACS Applied Materials and Interfaces, 13 (31), 37849-37861 (2021). 

(29) Zhen Yang^†, Xingwei Yang†, Rong Long*, Jianyu Li*, Stimulation modulates adhesion and mechanics of hydrogel adhesives, Langmuir, 37, 23, 7097–7106 (2021). 

(28) Shiyu Liu^, Guangyu Bao^, Zhenwei Ma^, Christian J. Kastrup, Jianyu Li*, Fracture mechanics of human blood clots: Measurements of toughness and critical length scales, Extreme Mechanics Letters, 101444 (2021). 

(27) Zhen Yang^, Zhenwei Ma^, Shiyu Liu^, Jianyu Li*, Tissue adhesion with tough hydrogels: Experiments and Modeling, Mechanics of Materials, 157, 103800 (2021). 

(26) Benjamin R. Freedman, et al., Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity, Nature Biomedical Engineering, In Press (2021). 

• Highly Cited Paper, i.e., the top one percent (1%) in the field of materials science, by Web of Knowledge. 

(25) Zhenwei Ma^, Guangyu Bao^, Jianyu Li*, Multifaceted design and emerging applications of tissue adhesives, Advanced Materials, 2007663 (2021). 

(24) Xiang Ni^, Zhen Yang^, Jianyu Li*, Scaling behavior of fracture properties of tough adhesive hydrogels, ACS Macro Letters, 10, 2, 180-185 (2021). 

(23) Binbin Ying^, Ryan Zeyuan Chen, Runze Zuo, Jianyu Li, Xinyu Liu, An anti-freezing, ambient-stable and highly stretchable ionic skin with strong surface adhesion for wearable sensing and soft robotics, Advanced Functional Materials, 2104665 (2020). 

• 2021 Top Downloaded Article in Advanced Functional Materials 
• Highly Cited Paper, i.e., the top one percent (1%) in the field of materials science, by Web of Knowledge. 

(22) Alexander Winkler-Schwartz, Recai Yilmaz, Dan Huy Tran, Houssem-Eddine Gueziri, Binbin Ying^, Marius Tuznik, Vladimir Fonov, Louis Collins, David A Rudko, Jianyu Li, Patricia Debergue, Valerie Pazos, Rolando Del Maestro, Creating a comprehensive research platform for surgical technique and operative outcome in primary brain tumor neurosurgery, World Neurosurgery, 144, e62-e71 (2020). 

(21) Zhenwei Ma^, Zhen Yang^, Qiman Gao, Guangyu Bao^, Amin Valiei, Fan Yang, Ran Huo^, Chen Wang, Guolong Song, Dongling Ma, Zu-Hua Gao, Jianyu Li*, Bioinspired tough gel sheath for robust and versatile surface functionalization, Science Advances, 7, 15, eabc3012 (2021). 

• This work is reported by McGill Newsroom: Surgical sutures inspired by human tendons.  

(20) Zhizhi Sheng, Mengchuang Zhang, Jing Liu, Paolo Malgaretti, Jianyu Li, Shuli Wang, Wei Lv, Rongrong Zhang, Yi Fan, Yunmao Zhang, Xinyu Chen, Xu Hou, Reconfiguring confined magnetic colloids with tunable fluid transport behavior, National Science Review, 8, nwaa301, (2020).

(19) Guangyu Bao^, Tao Jiang, Hossein Ravanbakhsh, Alicia Reyes, Zhenwei Ma^, Mitchell Strong, Huijie Wang, Joseph M. Kinsella, Jianyu Li*, Luc Mongeau*, Triggered micropore-forming bioprinting of porous viscoelastic hydrogels, Materials Horizons, 7, 2336-2347 (2020). 

•  Selected as the Back Cover of the issue of Materials Horizons. 

(18) Xiang Ni^, Chao Chen, Jianyu Li*, Interfacial fatigue fracture of tissue adhesive hydrogels, Extreme Mechanics Letters, 34, 100610 (2020). 

(17) Binbin Ying^, Qiyang Wu, Jianyu Li*, Xinyu Liu*, An ambient-stable and stretchable ionic skin with multimodal sensation, Materials Horizons, 7, 477-488 (2020). 

• This work presents the first design of ionic diode-based artificial skin that is capable to sense the change of deformation, force and humidity. 

(16) Serena Blacklow†, Jianyu Li†, Benjamin R. Freedman, Mahdi Zeidi, Chen Chao, David J. Mooney, Bioinspired mechanically active adhesive dressings to accelerate wound closure, Science Advances, 5, 7, eaaw3963 (2019). 

• This work present the first design of mechanically active wound dressings showing efficacy in accelerating wound healing. 
• Our work is highlighted in the top medical journal JAMA.
• News coverages: Harvard Gazette, Harvard Magazine, Wyss Institute, McGill News, Science, CBC Radio, La Presse, Science Codex, SciTechDaily, Physics World, First Post, The Medical News, Medical Health News, AlphaGalileo.
• Highly Cited Paper, i.e., the top one percent (1%) in the field of materials science, by Web of Knowledge. 

(15) Jiawei Yang, Ruobing Bai, Jianyu Li, Canhui Yang, Xi Yao, Qihan Liu,  Joost Vlassak, David Mooney, Zhigang Suo, Design molecular topology for wet-dry adhesion, ACS Applied Materials and Interfaces, 11, 27, 24802-24811 (2019).

(14) Jianyu Li, Eckhard Weber, Sabine Guth-Gundel, Michael Schuleit, Andreas Kuttler, Christine Halleux, Nathalie Accart, Arno Doelemeyer, Anne Basler, Bruno Tigani, Kuno Wuersch, Mara Fornaro, Michaela Kneissel, Alexander Stafford, Benjamin R. Freedman, David J. Mooney, Tough composite hydrogels with high loading and local release of biological drugs, Advanced Healthcare Materials, 7 (9), 1701393 (2018).

• This paper is ranked one of the most-read paper in February 2018 on Adv. Healthcare Mater., and has been highlighted by Advanced Science News. 

(13) Xu Hou†, Jianyu Li†, Alexander B. Tesler, Yuxing Yao, Miao Wang, Lingli Min, Zhizhi Sheng, Joanna Aizenberg, Dynamic air/liquid pockets for regulating microscale flow, Nature Communications, 9, 733 (2018).

(12) Jianyu Li, Adam Celiz†, Jiawei Yang†, Quanshan Yang, Isaac Wamala, William Whyte, Bo Ri Seo, Nikolay V. Vasilyev, Joost J. Vlassak, Zhigang Suo, David J. Mooney, Tough adhesives for diverse wet surfaces, Science, 357, 6349, 378-381 (2017). Supporting Information. IF 63. >1000 citations. 

• This paper reports the first report of tough biodhesives providing unprecedented adhesion performance on diverse wet surfaces.
• This work has gained worldwide media coverage, including 122 news outlets such as NPR, BBC, PBS, Washington Post, Newsweek, Science News, Forbes, Materials Today, CBS, Chemical and Engineering News, Voice of America, Popular Science, The Verge, The Guardian, Smithsonian Magazine, US News, Xinhua (新华网). 
• This work has been highlighted in the prestigious clinical journal - The New England Journal of Medicine. 
• Video highlights from Harvard Wyss Institute and Galileo TV.
• This paper quickly became a Hot paper, i.e., the top one-tenth of one percent (0.1%) in the field of materials science, by Web of Knowledge.
• This work is chosen and exhibited by Cooper Hewitt Design Museum in New York in an exhibition "Nature—Cooper Hewitt Design Triennial”. It is also selected by Discover Magazine's "One of Top 100 Discoveries" in 2017.

(11) Jingda Tang, Jianyu Li, Joost J. Vlassak, Zhigang Suo, Fatigue fracture of hydrogels, Extreme Mechanics Letters, 10, 24-31 (2017).

• This is a pioneer work on fatigue fracture of hydrogels, in which we applied fracture mechanics approach to investigate how a viscoelastic hydrogel fails under cyclic loads. 

(10) Jianyu Li, David J. Mooney, Designing hydrogels for controlled drug delivery, Nature Reviews Materials, 1, 16071 (2016). IF 74

• This review highlights a comprehensive material property chart of various hydrogel systems for controlled drug delivery. It has been cited  >450 times. 
• Hot paper, i.e., the top one-tenth of one percent (0.1%) in the field of materials science, by Web of Knowledge.  

(9) Sandeep T. Koshy, Rajiv M. Desai, Pascal Joly, Jianyu Li, Rishi K. Bagrodia, Sarah A. Lewin, Neel S. Joshi, David J. Mooney, Click-crosslinked injectable gelatin hydrogels, Advanced Healthcare Materials, 5, 541-547 (2016).

(8) Jingda Tang, Jianyu Li, Joost J. Vlassak, Zhigang Suo, Adhesion between highly stretchable materials, Soft Matter, 12, 4, 1093-1099 (2016).

(7) Jianyu Li, Zhigang Suo, Joost J. Vlassak, Stiff, strong, and tough hydrogels with good chemical stability, Journal of Materials Chemistry B, 2, 39, 6708-6713 (2014). >290 citations. 

• This paper is one of the 30 most accessed articles in the Journal of Materials Chemistry B in 2014.

(6) Mingyu Li, Jianyu Li, Joost J. Vlassak, Mechanical behavior of a poly(methyl methacrylate)-based ionogels, Soft Matter, 10, 40, 7993-8000 (2014). 

(5) Jianyu Li, Widusha R. K. Illeperuma, Zhigang Suo, Joost J. Vlassak, Hybrid hydrogels with extremely high stiffness and toughness, ACS Macro Letters, 3, 6, 520-523 (2014). >350 citations. 

• This paper was chosen to be the issue cover of ACS Macro Letters. 
• Highly Cited Paper, i.e., the top one percent (1%) in the field of materials science, by Web of Knowledge. 

(4) Jianyu Li, Zhigang Suo, Joost J. Vlassak, Model of ideal elastomeric gels for polyelectrolyte gels, Soft Matter, 10, 2582-2590 (2014).

(3) Xiangsheng Liu, Jieming Cao, Huan Li, Jianyu Li, Qiao Jin, Kefeng Ren, Jian Ji, Mussel-inspired polydopamine: a biocompatible and ultrastable coating for nanoparticles in vivo. ACS Nano, 7, 10, 9384-9395 (2013). 

• Highly Cited Paper, i.e., the top one percent (1%) in the field of materials science, by Web of Knowledge. 

(2) Jianyu Li, Yuhang Hu, Joost J. Vlassak, Zhigang Suo, Experimental determination of equations of state for ideal elastomeric gels, Soft Matter, 8, 31, 8121-8128 (2012). 

(1) Jianyu Li, Alfonso H.W. Ngan, Nanoscale fast relaxation events in polyethylene, Scripta Materialia, 62, 7, 488-491 (2010).