Professor of Biology
Building 68
Office 68 - 630B
31 Ames Street
Cambridge, MA 02139
Daniel Lew obtained a BA in genetics from Cambridge University (UK), and then a PhD in molecular biology working with James Darnell on interferon-stimulated transcription at the Rockefeller University (NY). After postdoctoral training on yeast genetics and cell cycle control with Steve Reed at the Scripps Research Institute (CA), he joined the Duke University faculty in 1994. His work has focused on the control of the cell cycle by cell shape and cytoskeletal stress, and on polarity establishment, with a view to understanding the universal problems of symmetry breaking and singularity (i.e. why a polarized cell has one and only one “front”). His group combines mathematical modeling with genetics/biochemistry/cell biology approaches to understand the design principles of the polarity machinery, and more recently the basis for effective tracking of pheromone gradients.
Postdoctoral Fellow
Alison is a postdoc in the Lew Lab interested in how cells deploy the cytoskeleton to organize and divide their cytoplasmic contents. She is investigating this using a combination of quantitative live-cell imaging and genetics in the unusual multi-budding yeast, Aureobasidium pullulans, which simultaneously produces many (10+) daughter cells each cell cycle. This creates unique challenges for the cell; for example, how does each daughter cell get at least one nucleus?
Postdoctoral Fellow
Yiqiao investigated the molecular mechanisms of inherited retinal diseases during her graduate studies, utilizing biochemistry, mouse genetics, and functional genomics. During this time, she became fascinated by the complex and elegant regulation of asymmetric cell division and cell fate specification during neurogenesis. In the Lew Lab, Yiqiao is currently exploring cell cycle control in Aureobasidium pullulans, an unusual yeast that produces multiple daughter cells in each cycle. This research offers a unique opportunity to unravel the versatile mechanisms governing cell division. Outside of the lab, Yiqiao enjoys a variety of sports, experimenting with new recipes, and spending time in museums.
PhD Candidate
Molecular Genetics and Microbiology
Erin is a PhD Candidate who came to Duke through the Molecular Genetics and Microbiology (MGM) program. She received her B.S. in biology at Syracuse University and decided to apply to graduate school after taking a gap year to explore different research fields and opportunities. In the Lew Lab she currently studying cell signaling by looking into how Saccharomyces cerevisiae identify mating partners and facilitate successful fusion. Outside of lab she enjoys checking out local restaurants, baking for friends, playing videos games, and watching anime!
PhD Candidate
Microbiology
Clara earned her B.S. Health Studies from the University of Waterloo and went on to work in industry for a couple of years before starting graduate school. She is a microbiologist whose job is to admire nature. Studying the complexity of the tiniest microbes gives her an appreciation for the beauty of all living things. In the lab, she is currently investigating how hyphal fungi (specifically Aureobasidium pullulans) sense their physical environments and navigate around obstacles.
PhD Student
Microbiology
Aarshi is interested in how microbes interact with each other and their environment. She holds a B.S. in Marine Biology and Computational and Systems Biology from the University of California, Los Angeles. Currently, Aarshi is investigating how fungi remodel their cell wall during natural processes without lysing. Her research focuses on the cell wall integrity pathway in the model organism Saccharomyces cerevisiae. In her free time, Aarshi enjoys reading, dancing, hiking, and sailing.
PhD Student
Microbiology
Avril is interested in microbial evolution, especially how genome evolution can give rise to the incredible diversity within the microbial world. She is currently investigating how A. pullulans can establish multiple polarity sites.
Natasha.Savage@liverpool.ac.uk
Principal Investigator
Department of Biology
University of Liverpool, UK
Department of Biosciences, School of Science
Kitasato University, 1-15-1 Kitasato, Sagamihara
Kanagawa 228-8555, Japan
Associate Professor
Department of Genetics and Biochemistry
Clemson University
Professor
Assistant Dean (School of Arts and Sciences)
State University of New York College at Brockport
Department of Biological Sciences
Postdoctoral Fellow
Laurie Boyer Lab and Yukiko Yamashita Lab
MIT and Whitehead Institute
Post-Doctoral Fellow
Masayuki Onishi and John Pringle Labs
Duke University
Assistant Research Fellow
Academia Sinica
Institute of Plant and Microbial Biology
allison.mcclure@cuanschutz.edu
Assistant Professor
Department of Biochemistry and Molecular Genetics
University of Colorado-Anschutz Medical Campus
Senior Research Scientist
Vertex Pharmaceuticals
Boston, Massachussetts
kindra.king@duke.edu
Investigator
Duke Office of Scientific Integrity
Duke University
Health Specialist Contractor
Office of Strategic Coordination
National Institutes of Health
Associate Professor
Microbiology and Physiological Systems
UMass Chan Medical School
Medical Technician
Hospital Transfusion Services
Oregon Health and Sciences University
Research Technician
Littman Lab
Skirball Institute of Biomolecular Medicine
NYU Langone Medical Center
Undergraduate Research Assistant
NIH IRTA Post-Baccalaureate
Lois Greene Laboratory
NHLBI
National Institutes of Health