Welcome to the Lei Wei laboratory

Exploring Cancer Genomics at Roswell Park Comprehensive Cancer Center

Research interests:

As a computational biologist, my researches focus on understanding the mechanisms of cancer initiation, progression, and prognosis through developing and utilizing computational methods. My recent research areas include:

· Identify driver mutation, etiology, mechanism, and heterogeneity in human & mouse cancer genomes.

· Ultra-sensitive detection of cancerous and precancerous lesions using somatic mutations.

· Develop innovative and integrative open-source computational software for analyzing genomics data.

· Accurate interpretation of complex genomic variants by haplotype-aware annotations.