Research field

• Development of biosensing platform, Synthesis of nanomaterials

Degree

• The sixth year of the Ph.D. degree, Ph.D. candidate

Awards

1. The Honorary Student English Oral Presentation Award in 2019 ICSS. 

2. The 2019 Academic Medal for Outstanding Paper from Association of Chemical Sensors in Taiwan (Co-author).

3. The Best Student English Oral Presentation Award in 2020 ICSS (Twice). 

4. The 2020 Academic Medal for Outstanding Paper from Association of Chemical Sensors in Taiwan (First author).

5. The Distinguished English Oral Paper Award in 2021 ICSS. 

6. The 2021 PhD Student Award from Association of Chemical Sensors in Taiwan.

7. The 2021 Academic Medal for Outstanding Paper from Association of Chemical Sensors in Taiwan (Co-author).

8. 國立中山大學 110 學年度工學院聯合專題競賽-特優

9. The first Prize Best Student English Oral Presentation Award in the International Conference on Precision Nanomedicine in Theranostics & the 2022 Annual Meeting of Taiwan Nanomedicine Society.

10. The Distinguished Oral Paper Award in 2022 ICSS.

11. The 2022 Academic Medal for Outstanding Paper from Association of Chemical Sensors in Taiwan (First author).

12. The Runners-up Oral Award Winners and  The Second Place Winner of People's Choice Award in 2024 ICSS.

13. The Outstanding oral presentation Award  in The 15th Asian Conference On Chemical Sensor (ACCS2024)

Publications

1. Lab-on-the-Needles: A Mobile Healthcare Sensing-Box for Sensitive Ex Vivo and In Vivo Protein Biomarker Detection. ACS Nano, accepted (2024)  (IF = 15.8)  

2. N.S. Li#, Y.P. Hsu#, H.H. Pang, S.F. Wang, S.T. Pang, C.Y. Lin, R.Y. Tsai, C.Y. Huang, K.C. Wei, H.W. Yang*. Lab-in-a-Vial Rapid Test for Internet of Things Imbedded Point-of-Healthcare Protein Biomarker Detections in Bodily Fluids. Small, 2400878 (2024). (IF = 13.0) https://doi.org/10.1002/smll.202400878

3. Microneedle Patch-Based SenBox for Highly Sensitive Detection and Quantification of Protein Biomarkers in Viscous Liquid Biopsy. accepted. ACS Nano (2024)

4. Metal-Organic Framework-Based Off-On Fluorescent Probe for Highly Selective and Sensitive Phosphate Detection. Nano Trends, Volume 7, 100051 (2024).

5. H.H Pang, N.S Li, Y.P. Hsu, S.P. Ju, G.D. Syu, P.X. Du, C.Y. Huang, K.C. Wei*, H.W. Yang*. AI-Driven Design System for Fabrication of Inhalable Nanocatchers for Virus Capture and Neutralization. Advanced Healthcare Materials, Volume 13, Issue 5, 2302927 (2024). (IF = 10.0) (Cover)

6. H.H. Pang, C.Y. Huang, P.Y. Chen, N.S. Li, Y.P. Hsu, J.K. Wu, H.F. Fan, K.C. Wei*, H.W. Yang*. Bioengineered bacteriophage-like nanoparticles as RNAi therapeutics to enhance radiotherapy against glioblastomas. ACS Nano 17, 10407–10422 (2023). (IF = 18.027) (Cover)

7. Y.J. Chen#, Y.P. Hsu#, Y.L. Tain#, N.S. Li, H.H. Pang, S.W. Kuo*, H.W. Yang*. Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic. Biosensors and Bioelectronics 208, 114234 (2022). (IF = 10.618)  

8. N.S. Li#, Y.T. Chen#, Y.P. Hsu, H.H. Pang, C.Y. Huang, Y.L. Shiue, K.C. Wei*, H.W. Yang*. Mobile healthcare system based on the combination of lateral flow pad and smartphone for rapid detection of uric acid detection in whole blood. Biosensors and Bioelectronics 164, 112309 (2020). (IF = 10.618)

9. W.L. Hsu#, C.Y. Huang#, Y.P. Hsu, T.L. Hwang, S.H. Chang, H.Y.J. Wang, L.Y. Feng, S.J. Tzou, K.C. Wei*, H.W. Yang*. On-skin glucose-biosensing and hyperglycaemia-triggered insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management. Chemical Engineering Journal 398, 125536 (2020). (IF = 13.273) 

10. Y.P. Hsu#, H.W. Yang#,*, N.S. Li, Y.T. Chen, H.H. Pang, S.T. Pang*. Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis. ACS Sensors 5,928-935 (2020).  (IF = 7.711)

11. Y.P. Hsu#, N.S. Li#, Y.T. Chen, H.H. Pang, K.C. Wei, H.W. Yang*. A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. Biosensors and Bioelectronics 151, 111960 (2020). (IF = 10.618)

12. N.S. Li#, W.L. Lin#, Y.P. Hsu, Y.T. Chen, Y.L. Shiue, H.W. Yang*. Combined Detection of CA19-9 and MUC1 Using a Colorimetric Immunosensor Based on Magnetic Gold Nanorods for Ultrasensitive Risk Assessment of Pancreatic Cancer. ACS Applied Bio Materials 2, 4847-4855 (2019).

13. P.C. Lee#, N.S. Li#, Y.P. Hsu, C. Peng, H.W. Yang*. Direct glucose detection in whole blood by colorimetric assay based on glucose oxidase-conjugated graphene oxide/MnO2 nanozymes. Analyst 144, 3038-3044 (2019). (IF = 4.616)

14. C. Peng#, M.Y. Hua#, N.S. Li, Y.P. Hsu, Y.T. Chen, C.K. Chuang, S.T. Pang*, H.W. Yang*. A colorimetric immunosensor based on self-linkable dual-nanozyme for ultrasensitive bladder cancer diagnosis and prognosis monitoring. Biosensors and Bioelectronics 126, 581-589 (2019). (IF = 10.618)

Conference Presentation

1. Y.P. Hsu, N.S. Li, H. W. Yang* (2024, Nov.). Innovative Microneedle Patch-based SenBox for Enhanced Detection of Protein Biomarkers in Complex Biological Fluids. The 15th Asian Conference on Chemical Sensors 2024 (ACCS2024), Kitakyushu, Japan.

2. Y.P. Hsu, Y.J. Chen, N.S. Li, H.H. Pang, Shao-Wei Kuo*, H. W. Yang* (2023, Sep.) Microneedle-Lateral Flow Cassette Integration for Blood-Free Point-of-Care Testing of Chronic Kidney Disease During a Pandemic. The 33rd Annual Conference of the European Society for Biomaterials (ESB2023), Davos, Switzerland.

3. N.S Li, Y.P. Hsu, H.H. Pang, H. W. Yang* (2022, Oct.) Revolutionary rapid testing vials kits for the ultrasensitive detection of early COVID-19 patients with asymptomatic seroconversion. 2022 International Conference on Smart Sensors (2022 ICSS), Taichung, Taiwan.

4. Y.P. Hsu, N.S Li, H. W. Yang* (2022, Oct.)  An ultrasensitive and rapid COVID-19 IgA and Spike RBD test in clinical saliva samples based on 3D microneedle patches. 2022 International Conference on Smart Sensors (2022 ICSS), Taichung, Taiwan.

5. Y.P. Hsu, N.S. Li, H.W. Yang* (2022, Jul).An ultrasensitive and rapid COVID-19 test based on 3D-microneedle patches for IgA and Spike RBD in clinical saliva samples. International Conferenceon Precision Nanomedicine in Theranostics & the 2022 Annual Meeting of Taiwan Nanomedicine Society, Hsinchu, Taiwan.

6. Y.P. Hsu, N.S Li, H. W. Yang* (2021, Oct.) Ultrasensitive and rapid COVID-19 tests for IgM, IgG, IgA and SARS-CoV-2 pseudovirus in clinical serological and saliva samples. 2021 International Conference on Smart Sensors (2021 ICSS), Taipei (Gather Town), Taiwan.

7. N.S. Li, Y.P. Hsu, H. W. Yang* (2020, Oct.) Development of Magnetic Immunoassay Platform for Rapid Cancer Biomarkers and Circulation Tumor Cells Detection. The 4th Global Conference on Biomedical Engineering & Annual Meeting on TSBME (2020 GCBME), Taipei, Taiwan.

8. N.S Li, Y.T Chen, Y.P Hsu, H.H Pang, Y.L Shiue, H. W. Yang* (2020, Oct.) Disposable enzyme-free µPAD-based biosensor for direct determination of uric acid in whole blood using a smartphone. 2020 International Conference on Smart Sensors (2020 ICSS), Kaohsiung, Taiwan.

9. Y.P. Hsu, N.S Li, H. W. Yang* (2020, Oct.) A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. 2020 International Conference on Smart Sensors (2020 ICSS), Kaohsiung, Taiwan.

10. Y.P. Hsu, N.S Li, Y.T Chen, H. W. Yang* (2020, Oct.) A Urological Point-of-care FXYD3 Test for Early Urothelial Carcinoma Screening and Postoperative Monitoring. 2020 International Conference on Smart Sensors (2020 ICSS), Kaohsiung, Taiwan.

11. N.S. Li, Y.T. Chen, Y.P. Hsu,  H. W. Yang* (2019, Jun.) A reusable enzyme-free biosensor based on mesoporous Prussian blue nanozyme functionalized PLA patch for rapid uric acid detection in serum. 6th International Conference on Bio-Sensing Technology, Kuala Lumpur, Malaysia.

12. Y.P. Hsu, N.S. Li, H. W. Yang* (2019, Jun.) A colorimetric biosensor based on antibody-conjugated Pt@Au nanozyme for simpler, faster, ultrasensitive Zika virus detection using smartphone. 6th International Conference on Bio-Sensing Technology, Kuala Lumpur, Malaysia.

13. N.S. Li, H.H. Pang, Y.P. Hsu,  H. W. Yang* (2019, Jun.) A Viral-Based Peroxidase-Like Gold Nano-Cluster Complex as Biosensor for Chemoresistance Prediction of Glioma Cells. 2019 International Conference on Smart Sensors (2019 ICSS), Hsinchu, Taiwan.

14. Y.P. Hsu, N.S. Li, H. W. Yang* (2019, Jun.) A colorimetric biosensor based on antibody-conjugated Pt@Au nanozyme for simpler, faster, ultrasensitive Zika virus detection using smartphone. 2019 International Conference on Smart Sensors (2019 ICSS), Hsinchu, Taiwan.

15. N.S. Li, Y.P. Hsu, Y.T. Chen, C. Peng, H.W. Yang* (2018, Jun). Magnetic liquid for rapid detection of CA19-9 and MUC1 in pancreatic cancer diagnosis. 28th Anniversary World Congress on Biosensors, Miami, USA.

16. Y.P. Hsu, N.S. Li, Y.T. Chen, C. Peng, S.T. Pang, H.W. Yang* (2018, Jun). A simple fabrication of biochip for home urothelial cancer diagnosis. 28th Anniversary World Congress on Biosensors, Miami, USA.