林岳謙

林岳謙

Yueh-Chien Lin (Daniel)

Master Student, Institute of Zoology, National Taiwan University

E-mail:d01b41001@ntu.edu.tw

Address: Room504, Department of Life Science, National Taiwan University

No. 1, Sec. 4, Roosevolt Road, Taipei, 106 Taiwan

Phone: +886-2-3366-2499 (O)

Research topics

前列腺癌為台灣男性十大癌症死亡原因之一，其發生率與死亡率有逐年上升的趨勢。目前治療的方式，依不同的期別包括：開刀、放射治療、荷爾蒙治療和化學藥物治療等，其中主要是以荷爾蒙治療為主。荷爾蒙治療包括睪丸切除，或使用抗雄性素作用之各種藥物。但賀爾蒙治療下的病人預後通常不是很好，並且容易發展成高度轉移性的癌細胞。因此我的研究是希望了解不同轉移性的前列腺癌細胞，對於LPA 造成的淋巴轉移之間的關係，未來可以應用在研發出更有效的抗癌藥物。

自我介紹

Daniel，台北縣淡水人，喜愛運動，最愛棒球和籃球，參加系上的籃球隊。夢想是能夠環遊世界，到各個地方體驗不同的文化和生活。

Education

B. S. Department of Life Science, National Taiwan University, June 2010

M. S. Institute of Zoology, National Taiwan University, June 2012

Research interest

Cancer biology

Award received

05/13 Outstanding Award The 11th NTU –Kyoto U Symposium on Molecular and Cell Biology

Conference presentation

1. CJ Shih, YC Lin, YL Huang, CL Chang, WP Huang and H Lee Sphingosine 1-phosphate-induced autophagy is mediated through activating endoplasmic reticulum stress response in human prostate cancer PC-3 cells. At 2010 The Leading Graduate School International Conference, Tsukuba, Japan. (Poster)

2. YC Lin and H Lee The study of androgen effect on LPA-induced VEGF-C expression in prostate cancer cell lines. At 2011 The 9th Kyoto U-NTU International Exchange Activity on Long-Distance Course, Kyoto, Japan. (Oral presentation & Poster)

3. YC Lin, CE Lin, YL Huang and H Lee The study of androgen effect on LPA-induced VEGF-C expression in prostate cancer cell lines. At 2011 The American Society for Cell Biology Annual Meeting Program, Denver, Colorado, USA. (Poster)

4. YC Lin, YL Huang and H Lee. The study of androgen effects on LPA-induced ROS in different human prostate cancer cell lines. At Experimental Biology 2012, San Diego, California, USA. (Poster)

5. YC Lin, YL Huang, and H Lee. The study of androgen effects on LPA-induced ROS in different human prostate cancer cell lines. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. (Oral presentation & Poster)

6. CC Lin, CE Lin, YC Lin, and H Lee. Lysophosphatidic acid induces reactive oxygen species generation through protein kinase C in PC-3 prostate cancer cells. At The 7th Tsukuba Medical Science Research Meeting, Tsukuba, Japan. (Poster)

7. CC Lin, YC Lin and H Lee.Lysophosphatidic acid induces reactive oxygen species generation through protein kinase C in PC-3 prostate cancer cells. At 2012 The American Society for Cell Biology Annual Meeting Program, San Fransico, California, USA. (Poster)

8. CI Chen, YC Lin, CC Chang, YM Cheng, KJ Chang, CN Chen and H Lee. Mechanism of connective tissue growth factor inhibited peritoneal metastasis in gastric cancer. ASCB2012:2426, P191, 2012. At 2012 The American Society for Cell Biology Annual Meeting Program, San Fransico, California, USA. (Poster)

9. YC Lin, PY Wu, SY Lan, YL Huang, H Lee Aryl Hydrocarbon Receptor Inhibits Lysophosphatidic Acid-Induced Vascular Endothelial Growth Factors Expression in Prostate Cancer Cells. At Experimental Biology 2013, Boston, Massachusetts, USA. (Poster)

10. YC Lin, PY Wu, SY Lan, YL Huang, H Lee Aryl Hydrocarbon Receptor Inhibits Lysophosphatidic Acid-Induced Vascular Endothelial Growth Factor-C Expression in Prostate Cancer Cells. The 11th NTU –Kyoto U Symposium on Molecular and Cell Biology, Kyoto, Japan. (Oral presentation)

Research Paper

1. CE Lin, SU Chen, CC Lin, CH Chang, YC Lin, YL Tai, TL Shen and H Lee. Lysophosphatidic acid acts as an autocrine factor to enhance vascular endothelial growth factor-C expression in human prostate cancer PC-3 Cells. Plos One. 7(7): e41096. June 2012. (4.411, 12/86, 2010)

2 .BJ Wang, PY Wu, YC Lu, CH Chang, YC Lin, TC Tsai, MC Hsu, H Lee. Establishment of a cell-free bioassay for detecting dioxin-like compounds. Toxicol Mech Methods. 23(6):464-70. July 2013

3. PY Wu, YC Lin, SY Lan, YL Huang, H Lee. Aromatic hydrocarbon receptor inhibits lysophosphatidic acid-induced vascular endothelial growth factor-A expression in PC-3 prostate cancer cells. Biochem Biophys Res Commun. 437(3):440-5. August 2013