K.E.M.
Radiology
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Department of Radiology
Seth G.S. Medical College and K.E.M. Hospital, Mumbai , India
Case of the Month
Gossypiboma mimicking a solitary fibrous tumor of the retroperitoneum
Contributed by: Zubin Driver
Introduction:
The name "gossypiboma" is derived from two Latin words, Gossypium- cotton and boma- a place to hide. Gossypiboma are retained surgical sponges in the body. The most common site is in the abdominal cavity. The chest, brain, extremities, and breasts are rare sites [1]. Due to fear of medicolegal consequences, the actual incidence remains underrated. The fibrotic reaction around the gauze piece can mimic an aggressive fibrous neoplasm like a solitary fibrous tumor. Solitary fibrous tumors are neoplasms of mesenchymal origin. They show lobulated enhancing fibrous mass with central areas of necrosis. Here we present a case of a well-encapsulated enhancing soft tissue mass in a 69-year-old man.
Clinical Profile:
A 69-year-old man came with complaints of low backache for six months. He had a history of live donor renal transplant in 2003 for chronic kidney disease. He had no history of trauma, weight loss, or fever. On examination, there was a scar in the right iliac fossa. There was no palpable lump.
His current serum creatinine levels were in the normal range. He was on triple immunosuppressants (low-dose corticosteroids + azathioprine + cyclosporine).
Radiological investigations:
A curvilinear ultrasound probe placed transversely in the hypogastric region(Figure 1 A) showed a lobulated heterogeneously isoechoic lesion with a central anechoic area and post acoustic shadowing, adjacent to the right common iliac vessel. On colour Doppler, vascularity was not demonstrated in the lesion (Figure 1 B).
Figure 1 A, B: Ultrasonogram shows a well-defined lobulated heterogeneously isoechoic lesion with central anechoic area and post acoustic shadowing. The periphery of lesion shows no vascularity on the colour Doppler.
On the CT scan (Figure 2 A), the lesion is hypodense (average attenuation of 35 HU), measuring 8 x 8 x 9.5 cm ' located medial to the transplanted kidney in the hypogastrium and arising from the endopelvic fascia. It abuts the transplanted renal artery without any significant mass effect or loss of fat planes. There were a few discrete foci of calcification in the lesion. The lesion showed heterogeneous peripheral enhancement in the arterial phase with progressive peripheral enhancement in the venous (Figure 2B) and delayed phases (Figure 2 C). The transplanted kidney was normal.
Figure 2 A, B, C: Plain, venous, and excretory phase axial CT scans of the abdomen show a well-defined hypodense lesion medial to the transplanted kidney with no mass effect or loss of fat planes. It shows heterogeneous peripheral enhancement in the venous phase with progressive peripheral enhancement in the delayed phase.
On MRI, the lesion showed a T2 hyperintense (Figure 3 A) /T1 hypointense (Figure 3 B) center with a thick lobulated T2/T1 isointense capsule. The peripheral capsule had a few foci of diffusion restriction (Figure 3 C) with corresponding drop on ADC map (Figure 3 D). These features pointed towards a fibrous lesion with a necrotic center.
Figure 3 A, B: MRI shows T2 hyperintense/T1 hypointense center with a thick lobulated isointense capsule.
Figure 3 C, D: The capsule shows few foci of diffusion restriction and corresponding hypointensity on the ADC map.
A whole-body PET CT was done to rule out lymph nodal or hematogenous metastasis(Figure 4). PET CT showed low metabolic FDG uptake (SUV max of 5.27) along the periphery of the mass lesion. There was no uptake in the center.
Radiological diagnosis:
Based on imaging features, the differentials considered were:
1. Solitary fibrous tumor
2. Retroperitoneal sarcoma
3. Malignant peripheral nerve sheath tumor
Treatment:
The patient underwent laparotomy with the excision of mass under general anaesthesia.
Pathological diagnosis:
The gross morphology of the cut specimen showed a central cavity with old gauze and necrotic material with a surrounding thick whitish capsule.
Microscopy showed a thick encapsulated mass composed of fibrotic material surrounding an old gauze and suture material. There were multiple multinucleated giant cells with surrounding fibrosis. There was no evidence of tuberculosis or malignancy.
Fig. 5 : Excised operative specimen