About me 

I am Jordi Sevilla Fortuny, a biologist studying a Master's in Bioinformatics at the Universitat de València (Spain). My research spans genomic epidemiology of Klebsiella pneumoniae, antimicrobial resistance genomic prediction using machine learning and within-host evolution in SARS-CoV-2. Currently contributing to the EpiMol group through a Spanish government fellowship. I bring expertise in Python, R, and Bash for computational analyses.

Education

• MS in Bioinformatics

  • Institution: Universitat de València (Spain)

  • Period: 09/2023 - 05/2025

  • Remarks: Master's thesis on developing a pipeline for refining pangenomes for robust phylogenetic analyses in Klebsiella pneumoniae. (Work in progress)

• Degree in biology (8.67/10)

  • Institution: Universitat de València (Spain)

  • Period: 09/2019 - 06/2023

  • Remarks: My final thesis focuses on employing machine learning for genomic prediction of antimicrobial resistance in Klebsiella pneumoniae and elucidating the underlying mechanisms. (grade: 9.7/10)

Work Experience

• Granted intern

  • Institution: Joint Research Unit Infection and Public Health FISABIO-University of Valencia, Valencia, Spain. (PI: Fernando González Candelas)

  • Period: 10/2023 - 05/2025

  • Description: Extension of my bachelor’s thesis project: Development of enhanced machine learning methods for improved prediction and understanding of fosfomycin, amikacin, and pip/taz resistance in Klebsiella pneumoniae through genomic data.

• Granted intern

  • Institution:  Institute for Integrative Systems Biology (I2SysBio, University of Valencia - CSIC), FISABIO Joint Research Unit “Infection and Public Health”, Paterna, Spain. (PI: Mireia Coscollá Devis)

  • Period: 03/2023 - 09/2023

  • Description: Exploring within-host evolution in chronic SARS-CoV-2 infections through advanced analyses. Additionally, developing bioinformatic tools for precise detection and characterization of prolonged viral states (VIPERA).

• Curricular internship

  • Institution: Joint Research Unit Infection and Public Health FISABIO-University of Valencia, Valencia, Spain. (PI: Fernando González Candelas)

  • Period: 10/2022 - 07/2023

  • Description:  Temporal Evolution of Antimicrobial Resistance: Insights from a Decade-Long Surveillance of Klebsiella pneumoniae infections in the Comunitat Valenciana (Spain)

• Colaborator student

  • Institution: Joint Research Unit Infection and Public Health FISABIO-University of Valencia, Valencia, Spain. (PI: Fernando González Candelas)

  • Period: 09/2020 - 09/2022

  • Description: During my tenure as a collaborating student in the Genetics Department at the Universitat de València, I assisted Dr. Neris García González in the final stages of her doctoral thesis, titled 'Genomic Epidemiology and Antimicrobial Resistance of Klebsiella pneumoniae in the Comunitat Valenciana.'

Courses and qualifications

• Introduction to artificial inteligence with python | CS50 (Harvard) | 11-2023

• Introduction to Programming with Python | CS50 (Harvard) | 07-2024

• Bioinformatics for Biologists | Wellcome Connecting Science Learning and Training | 10-2023

• Antimicrobial databases and genotype prediction:  Data sharing and analysis | Wellcome Connecting Science Learning and Training | 10-2024

• IELTS academic - band 7.5 | IELTS international | 09-2024

Grants 

• Collaboration Fellowship | Spanish goberment | 10-2023

• JAE INTRO grant | Spanish National Research Council (CSIC) | 03-2023

Posters and communications at conferences

• "Tracking intra host evolution of SARS-CoV-2" (poster) | ViBioM | 2023 | Best scientific poster award

• “VIPERA: A robust pipeline for studying serially sampled SARS-CoV-2 infections" (poster)  | MEEGID | 2023

• "Temporal dynamics of antimicrobial resistance in Klebsiella pneumoniae in the Valencian community (2010-2022)" (poster)  | SEIMC | 2024

• "Overexpression of ABA receptor PYL1 enhances drought tolerance in Nicotiana benthamiana through agonist combinations" (poster)  | IBC | 2024

• "Improving core genome gene alignments for large-scale evolutionary and transmission studies of bacteria" (poster)  | SEBiBC | 2024

• "Automated assessment of SARS-CoV-2 intra-patient datasets with VIPERA" (poster)  | SEBiBC | 2024

• "Improving genomic prediction of AMR in K. pneumoniae using machine learning" (poster)  | SEBiBC | 2024

• Improving genomic prediction of AMR in K. pneumoniae using machine learning" (poster)  | KLEBS24 | 2024

Publications

• Tracking the Emergence and Dissemination of a blaNDM-23 Gene in a Multidrug Resistance Plasmid of Klebsiella pneumoniae

García-González N, Beamud B, Fuster B, Giner S, Domínguez MV, Sánchez A, Sevilla J, Coque TM, Gimeno C, González-Candelas F; Networked Laboratory for Antimicrobial Resistance Surveillance of Comunitat Valenciana (Spain). Tracking the Emergence and Dissemination of a blaNDM-23 Gene in a Multidrug Resistance Plasmid of Klebsiella pneumoniae. Microbiol Spectr. 2023 Feb 1:e0258522. doi: 10.1128/spectrum.02585-22. Epub ahead of print. PMID: 36722967.

• VIPERA: Viral Intra-Patient Evolution Reporting and Analysis

Miguel Álvarez-Herrera & Jordi Sevilla, Paula Ruiz-Rodriguez, Andrea Vergara, Jordi Vila, Pablo Cano-Jiménez, Fernando González-Candelas, Iñaki Comas, Mireia Coscollá, VIPERA: Viral Intra-Patient Evolution Reporting and Analysis, Virus Evolution, Volume 10, Issue 1, 2024, veae018, https://doi.org/10.1093/ve/veae018.

• Temporal evolution of antimicrobial resistance: insights from a decade-long surveillance of Klebsiella pneumoniae infections in the Comunitat Valenciana (Spain) (preprint)

Jordi Sevilla Fortuny, Pilar Ausina Aguilar, Maria Elena Vidal et al. Temporal evolution of antimicrobial resistance: insights from a decade-long surveillance of Klebsiella pneumoniae infections in the Comunitat Valenciana (Spain), 28 March 2024, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-4145011/v1].

• Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020

García-González, N., Beamud, B., Sevilla-Fortuny, J. et al. Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020. Antimicrob Resist Infect Control 14, 44 (2025). https://doi.org/10.1186/s13756-025-01553-2

• Improved prediction of antimicrobial resistance in Klebsiella pneumoniae using machine learning (preprint)

Jordi Sevilla-Fortuny, Fernando González-Candelasa,, Neris García-González, Improved prediction of antimicrobial resistance in Klebsiella pneumoniae using machine learning. Available at biorxiv: https://www.biorxiv.org/content/10.1101/2024.12.10.627815v1