The strongly reduced number of bursts suggested that HER2 lockdown by bipDARPins reduces mobility at length scales on the order of the size of the confocal volume. To explore the spatiotemporal re-organization of HER2 by bipDARPins with sub-diffraction resolution and to directly visualize immobile HER2-DARPin complexes, we turned to SMLM. For this purpose, we transiently expressed HER2 fused to an N-terminal SNAPf tag27 in HeLa cells. After simultaneous labeling with DY-549P1 and DY-649P1, we performed time-lapse dual-color total internal reflection fluorescence microscopy (TIRFM) for tracking and co-tracking individual HER2 in the basal plasma membrane of living cells. To ensure reliable single-molecule localization and tracking, cells with an observable particle density

To establish a fair comparison across different research studies and reflect the state-of-the-art of the technology, this paper provides an in-depth review of important aspects of existing fall detection experiments, including sensor types and positions, data collection protocols, subject groups, feature extractors, classification methods, and performance measures. Apart from a detailed summary of existing research studies, we also present an overview of available commercial products and future research directions of automatic fall monitoring. Commercial products are described and compared based on size, weight, sensor type, battery, transmission range, and features. The use of mobile devices, including smart phones, as the hardware platform is becoming increasingly popular. They can be used not only for motion sensing, but also for storing profiles, communication and detecting users' locations. In addition to fall alerts, a user's location or co-location is also another important information that allows timely assistance and intervention. Although smart phones are already being carried by users on a daily basis and seem to be a promising solution for fall monitoring, there still exist many issues to be addressed, i.e., sensor fixation, varied sensor quality, and battery lifetime. At the moment, dedicated-designs of wearable fall sensors with constraint positioning are still relatively better in terms of battery lifetime and achievable accuracy.


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Ease of locating and accessing research articles prompted the Logan University Learning Resources Center to begin utilizing Read by QxMD. It allows the user to follow specific journals for new content, search for literature, set up key word alerts, and curate collections. On the library's end, we can gather analytics, determine gaps in the collection, allow seamless linking to our full text, create subject-specific collections for our users to follow, and offer request-a-copy service to our patrons. While Read is available on various platforms, the majority of Logan users prefer using the mobile app. Objective: Librarians strive to get users in the Logan community to continue using the Read by QxMD resource after creating accounts. During the first trimester of the chiropractic program, students sign up for a Read by QxMD account in their information literacy course. Faculty are encouraged to use the resource via e-mail communication and workshops. Method: Data are gathered through an analytical dashboard that provides information on patron usage, journal insights, and accession data. Results: After promoting the use of Read by QxMD for the past 5 years, the number of users has increased from 79 to over 1260. In May 2022, 33% of those users remained active. Conclusion: The Read by QxMD resource has continually connected students and faculty of Logan University to research articles while allowing the library to offer its services in an easy-to-access manner. (This is a conference presentation abstract and not a full work that has been published.)

This is a required capstone project developed during the 2nd year of the doctor in chiropractic program with the participation of several biomedical courses. Students must incorporate design thinking principles to create a prototype of a program to address behavior change, wellness, and self-care of themselves and their community. Students choose a topic, theme, or hobby about which they are passionate; investigate the relationship of this topic with biomedical concepts; and craft a proposal focused on strengthening wellness and promoting the health of patients and themselves. Students develop the projects during the term of the courses, receive periodic feedback from participant faculty, and share their final projects in TED-style presentations open to the academic community. Projects are evaluated through a 360-degree assessment strategy including both group and individual evaluation. Since its implementation in 2020, a total of 12 innovative projects have been developed within the 6 pillars of lifestyle medicine: healthy nutrition and culinary medicine, physical activity, sleep health, stress management, control of toxic habits, and meaningful relationships. Evaluation results have demonstrated accomplishment of the learning goals aligned with the competencies of the program while providing solutions to real-world problems. Students have expressed satisfaction and enjoyment with the project, and participant faculty have identified new avenues to assess high-order thinking. The university is compromised with the implementation of the projects in the near future as part of the institutional wellness program and community service. The model can be applied to other disciplines and be part of interprofessional approaches. (This is a conference presentation abstract and not a full work that has been published.) be457b7860

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