iMOD-S Lab

Integrated laboratory of Metabolism, Obesity, and Diabetes

Welcome to the integrated laboratory of Metabolism, Obesity, Diabetes–Suh (iMOD-S)!
Our research focuses on understanding the processes that are involved in the regulation and execution of metabolism. While we are interested in understanding metabolism from a variety of angles, the lab currently focuses on adipose tissue, muscle, brain and the exocrine pancreas in normal and pathological states. Our research primarily utilizes mouse models along with various cellular and molecular tools to address questions in the following areas:

• FGF1 signaling in metabolism and tissue homeostasis

• Mechanisms governing adipocyte plasticity, dedifferentiation and adipose tissue remodeling

• Regulation of leptin expression and its effect on systemic energy homeostasis

• Adaptive response to fasting in brown adipose tissue thermogenesis

• In vivo analysis of tissue-specific proteomes at subcellular resolution by proximity labeling

• Regulation of mitochondrial structure and function by mitochondrial proteins

• Role of ERRγ in acinar cell identity, transdifferentiation and tumorigenesis

OPEN POSITIONS: We are seeking talented and motivated students and post-docs to join our research team! Undergraduate interns are welcome as well. Please contact Dr. Suh by email at jmsuh@kaist.ac.kr