Prior Academic Affiliations:
Bachelor of Science (China Pharmaceutical University)
Master of Pharmacy (China Pharmaceutical University)
Thesis Mentor: Steven Rosen
Thesis Project:
Target acute myeloid leukemia with a combination of venetoclax and 8-chloro-adenosine or 8-amino-adenosine
Fellowships, honors, awards etc :
Three-Minute Thesis Competition Winner (COH, 2022);
RSO First Prize Poster (COH, 2022);
Held Fellowship (COH, 2020);
Berger Fellowship (COH, 2019);
Excellent Graduate (CPU, 2019);
Grand Prize Scholarship (CPU, 2017 & 2018);
Outstanding Graduate Student (CPU, 2018);
Livzon Innovation Fund First Prize Scholarship (2017);
Nanjing Innovation and Entrepreneurship Award (2017);
Excellent volunteer of CPU (2016);
Excellent volunteer of Youth Olympic Games (2014);
(COH: City of Hope; CPU: China Pharmaceutical University)
Publications :
Guo J, Yang Y, Buettner, R., Rosen, S. T. (2022). Targeting the Methionine-MAT2A-SAM Axis for Cancer Therapy/ Curr Opin Oncol, 2022, 32:000–000, DOI:10.1097/CCO.0000000000000870
Hoang, D. H., Morales, C., Rodriguez, I. R., Valerio, M., Guo, J., Chen, M. H., Wu, X., Horne, D., Gandhi, V., Chen, L. S., Zhang, B., Pullarkat, V., Rosen, S. T., Marcucci, G., Buettner, R., & Nguyen, L. (2022). Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism. Cancers, 14(6), 1446. https://doi.org/10.3390/cancers14061446
Cao S*, Guo J* (Co-first author), He Y, Alahdal M, Tang S, Zhao Y, Yang Z, Gao H, Hu W, Jiang H, Qin L, Jin L. Nano-loaded human umbilical cord mesenchymal stem cells as targeted carriers of doxorubicin for breast cancer therapy. Artif Cells Nanomed Biotechnol. 2018;46(sup1):642-52. Epub 2018/02/20. doi: 10.1080/21691401.2018.1434185. PubMed PMID: 29457930.
Zhao Y, Tang S, Guo J, Alahdal M, Cao S, Yang Z, Zhang F, Shen Y, Sun M, Mo R, Zong L, Jin L. Targeted delivery of doxorubicin by nano-loaded mesenchymal stem cells for lung melanoma metastases therapy. Sci Rep. 2017;7:44758. Epub 2017/03/18. doi: 10.1038/srep44758. PubMed PMID: 28303966; PMCID: PMC5355993.
Li L, Li JY, Guo JM, Zhang HK, Zhang X, Yin CY, Wang LM, Zhu YS, Yao QQ. 3D Molecularly Functionalized Cell-Free Biomimetic Scaffolds for Osteochondral Regeneration. Adv Funct Mater. 2019;29(6). doi: ARTN 1807356 10.1002/adfm.201807356. PubMed PMID: WOS:000458339800019.
Li L, Li JY, Guo JM, Zhang HK, Zhang X, Yin CY, Wang LM, Zhu YS (Presenter), Yao QQ. “Nano-patterned Bilineage Scaffolds Coated by Self-assembly Peptide Hydrogels for Simultaneous Osteochondral Regeneration.” 2019 International Conference on Functional Materials Technology, AAAFM-UCLA, Los Angeles, CA.
Zhao XS, Guo JM, Zhang FF, Zhang J, Liu DL, Hu WJ, Yin H, Jin L. Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot. Stem Cell Res Ther. 2020;11(1). doi: ARTN 394 10.1186/s13287-020-01825-1. PubMed PMID: WOS:000573614500001.
Zhang FF, Ma DS, Liu TS, Liu YH, Guo JM, Song J, Wu Q, Pan Y, Zhang YF, Guo CY, Teng CB, Jin L. Expansion and Maintenance of CD133-Expressing Pancreatic Ductal Epithelial Cells by Inhibition of Transforming Growth Factor-beta Signaling. Stem Cells Dev. 2019;28(18):1236-52. doi: 10.1089/scd.2019.0087. PubMed PMID: WOS:000480440100001.
Song J, Ma DS, Xing Y, Tang SS, Alandal M, Guo JM, Pan Y, Zhang YF, Shen YM, Wu Q, Lu Z, Jin L. Alpha-Ketoglutarate Promotes Pancreatic Progenitor-Like Cell Proliferation. Int J Mol Sci. 2018;19(4). doi: ARTN 943 10.3390/ijms19040943. PubMed PMID: WOS:000434978700022