Prior Academic Affiliation: B.Sc. and M.Sc. from Universität zu Lübeck, Germany
Thesis Mentor: Dr. Daniela Castanotto and Dr. Cy Stein
Thesis Title: Development of a Multifunctional Oligonucleotide for the Treatment of Glioblastoma Multiforme
Fellowships, honors, awards etc:2016, Travel Scholarship, German Academic Exchange Service; 2018, H.N. & Frances Berger Foundation Fellowship
Publications:
Biscans A, Bertrand JR, Dubois J, Rüger J, Vasseur JJ, Sczakiel G, Dupouy C, Debart F. (2016) Lipophilic 2'-O-Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery. Chembiochem: a European journal of chemical biology. 17: 2054-62. PMID: 27569765
Castanotto D, Zhang X, Alluin J, Zhang X, Rüger J, Armstrong B, Rossi J, Riggs A, Stein CA. (2018) A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 115: E5756-e65. PMID: 29866826; PMCID: PMC6016802