Prior Academic Affiliation: B.S. National Dong Hwa University, Taiwan, M.S. University of Southern California
Thesis Mentor: Stephen Forman MD and Christine Brown Ph.D
Thesis Title: Meditope-enabled Chimeric Antigen Receptor Confers New Functionality to the T cells
Publications:
Autophagy required for hepatitis B virus replication in transgenic mice., Tian Y, Sir D, Kuo CF, Ann DK, Ou JH, J Virol. 2011 Dec;85(24):13453-6
Viral-load-dependent effects of liver injury and regeneration on hepatitis B virus replication in mice., Tian Y, Chen WL, Kuo CF, Ou JH., J Virol. 2012 Sep;86(18):9599-605
Enhancement of hepatitis B virus replication by androgen and its receptor in mice., Tian Y, Kuo CF, Chen WL, Ou JH., J Virol. 2012 Feb;86(4):1904-10
Replication of hepatitis C virus RNA on autophagosomal membranes, Sir D, Kuo CF,Tian Y, Liu M, Huang E, Jung JU, Machida K, Ou JH, J Biol. Chem. 2012 May 25; 287(22): 18036–18043
Autophagy inhibits oxidative stress and tumor suppressors to exert its dual effect on hepatocarcinogenesis., Tian Y, Kuo CF, Sir D, Wang LY, Govindarajan S, Petrovic L, Ou JH, Cell Death Differ. 2015 Jun;22(6):1025-34
Maternal Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission., Tian Y, Kuo CF*, Akbari O, Ou JH. , Immunity. 2016 May 17;44(5):1204-14
Mechanisms of Hepatitis B Virus Persistence., Tsai KN,Kuo CF, Ou JJ, Trends Microbiol. 2018 Jan;26(1):33-42
IL-15-mediated reduction of mTORC1 activity preserves the stem cell memory phenotype of CAR-T cells and confers superior antitumor activity, Alizadeh D, Wong RA, Yang X, Wang D, Pecoraro JR, Kuo CF, Aguilar B, Qi Y, Ann DK, Starr R, Urak R, Wang X, Forman SJ, Brown CE.