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Looking to Buy Hydrocodone in USA Legally
Hydrocodone is a generic drug sold under the brand name Hysingla and others. It is an opioid analgesic to treat severe long-term pain when other treatment options are not enough.
People also Buy Hydrocodone Online in USA to suppress cough in adults. It is an oral medication generally available in combination with paracetamol and ibuprofen. As a single-ingredient product, it comes only as a long-acting formulation medication.
Hydrocodone was patented in 1923 and its long-acting formulation was approved for medical use in 2013 in the United States. The wholesale cost of long-acting hydrocodone is about $10 to $30 per dose as of 2019.
It is one of the most commonly prescribed drugs in the United States, consuming 80-90% of the world's supply of hydrocodone.
Manufacturers obtain hydrocodone from opium poppy after converting it to codeine. It is almost similar to morphine in terms of efficacy and effectiveness.
What are the Uses of Hydrocodone?
What are the Uses of Hydrocodone?
You can Order Hydrocodone Online without Preception to treat moderate to chronic pain. Its liquid formulation is helpful in the treatment of cough. A study comparing the potency of hydrocodone and oxycodone shows that oxycodone is about 50% more potent than it.
However, a study of emergency department patients with fractures shows that equal amounts of both drugs provided the same analgesic effects, indicating that there is little practical difference between these two when used for the same purpose.
The analgesic actions of hydrocodone usually start within 20 to 30 minutes and last about 4 to 6 hours. Therefore, it is recommended that the dosage interval be generally 4 to 6 hours.
Are There Side Effects of Hydrocodone?
Are There Side Effects of Hydrocodone?
Hydrocodone also causes side effects along with its necessary effects. The most common side effects include:
Constipation
Nausea
Vomiting
Dizziness
Drowsiness
Daze
Humor changes
Anxiety
Dry throat
Difficult urination
Acne
Itching
Pupil contraction
Its misuse can cause progressive bilateral hearing loss that is unresponsive to steroid therapy. This adverse reaction is rare and occurs due to the toxicity of hydrocodone.
The drug is in the US Food and Drug Administration pregnancy category C. A baby born to a mother who takes hydrocodone regularly will be physically dependent on the drug. The baby could develop respiratory depression if doses are high.
Hydrocodone can be habit-forming, even at recommended doses. It can cause physical or psychological dependence and has a high potential for abuse and addiction.
How Does Hydrocodone Affect Our Body?
How Does Hydrocodone Affect Our Body?
Hydrocodone is a selective full agonist at mu-opioid receptors. It is the main target of endogenous opioids. Hydrocodone has less affinity for the delta-opioid receptor (DOR) and k-opioid receptor (KOR).
Studies show that hydrocodone is more potent than codeine in binding to receptors, but only 59% more potent than morphine in terms of analgesic properties. However, animal tests show that the analgesic potency of hydrocodone is greater than that of morphine.
What Drugs Interact With Hydrocodone?
What Drugs Interact With Hydrocodone?
Hydrocodone interacts with several drugs to produce additive central nervous system depression. If you are taking this medication dose, avoid taking alcohol, any other opioids, alcoholic beverages, antipsychotics, anticholinergics, antihistamines, anxiolytics, or other central nervous system depressants. It also interacts with serotonergic medications to produce serotonin syndrome.
You should not take any drug that interacts with hydrocodone at the same time. Consult your prescribing physician and request a complete list of all interacting prescription and non-prescription medications and other drugs.
What are the Available Dosage Formulations of Hydrocodone?
What are the Available Dosage Formulations of Hydrocodone?
You can order hydrocodone online in both single-ingredient and combination formulations. It comes in a variety of formulations for oral administration:
The original single-ingredient form of hydrocodone is Dicodid, in 5 mg and 10 mg immediate-release tablets.
A combination of hydrocodone and homatropine, Hycodan, are small tablets to treat cough.
Extended-release hydrocodone is available as an extended-release syrup containing chlorpheniramine, known as Tussionex. It is also a popular cough medicine in North America.
A combination of hydrocodone and acetaminophen in immediate-release tablets, namely Lortab, Vicodin, Norco, Lorcet, Zydone, and Maxine.
A combination of hydrocodone and ibuprofen as immediate-release tablets, namely Ibudone, Vicoprofen, and Reprexain.
A combination of hydrocodone and aspirin in immediate-release tablets, namely Lortab ASA, Alor 5/500, Panasal 5/500, and Azone.
Controlled-release hydrocodone such as Zohydro ER or Hysingla ER.
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